A Zakrzewski

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Arterial blood pressure estimation using ultrasound: Clinical results on healthy volunteers and a medicated hypertensive volunteer

A Zakrzewski Brian W. Anthony

This study presents a non-occlusive and non-invasive ultrasound-based technique to measure blood pressure. Most popular clinically-used arterial blood pressure measurement techniques suffer from important weaknesses including being inaccurate, invasive, or occlusive. In the proposed technique, an ultrasound probe is placed on the patient's carotid artery and the contact force between the probe and the tissue is slowly increased while ultrasound images and contact force data are recorded. From this data, the artery is segmented and the segmentation data is sent into an optimization procedure; after post-processing, blood pressure is displayed to the user. This technique was applied to 24 healthy single-visit volunteers, one multi-visit healthy volunteer, and one multi-visit medicated hypertensive volunteer. Compared to the oscillometric cuff, the accuracy and precision of the algorithm-reported systolic pressure is -2.4 ± 10.2 mmHg, and for diastolic pressure is -0.3 ± 8.2 mmHg. This method has the potential to occupy a clinical middle-ground between the arterial catheter and the oscillometric cuff.

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10.1109/embc.2017.8037281

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Multi-scale quantitative elastography and its application to blood pressure estimation

A Zakrzewski

Elastography is a method that can be used to measure the elasticity of soft biological tissue and, ultimately, to detect cancerous tumors. In this thesis, quantitative compression based ultrasound elastography is developed using a fast multi-scale approach. The inverse problem optimization methods of elastography are applied to estimate noninvasively the arterial wall stiffness of a vessel as well as blood pressure. Simulation and experimental results are presented that predict the accuracy of the methods. A method is also introduced to eliminate the need for a reference pressure during the optimization over blood pressure. Using ultrasound, these techniques could provide noninvasive continuous measurement of blood pressure in major arteries and could give doctors another way to gather information about a patients cardiovascular health.

Ultrasound Elastography

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Citations (3)

[Surgical treatment of laryngeal neoplasms with the method of Leroux-Robert].

PubMed (1968)

A Zakrzewski

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[APROPOS OF CLOSING LARGE POSTOPERATIVE RETROCOCHLEAR FISTULAE USING REVERSED MUSCULO-PERIOSTEAL FLAPS].