Nguyen Thi Nhu Ngoc

Vietnam National University Ho Chi Minh City

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Jennifer Blum

Mathematica Policy Research

Beverly Winikoff

Gynuity Health Projects

Sheila Raghavan

Gynuity Health Projects

Beverly Winikoff

Gynuity Health Projects

Rasha Dabash

University of North Carolina at Chapel Hill

Nguyen Thi Bach Nga

Development Fund

Paul D. Blumenthal

Stanford University

Jill Durocher

Gynuity Health Projects

Ilana G. Dzuba

Gynuity Health Projects

Ayisha Diop

Gynuity Health Projects

Cooperative Institutions

Gynuity Health Projects

World Health Organization

RELX Group (United States)

RELX Group (United Kingdom)

Centro Rosarino de Estudios Perinatales

Hung Vuong Hospital

King's College London

Planned Parenthood

University of the Philippines Diliman

World Health Organization - Pakistan

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I86 Treatment of postpartum hemorrhage with sublingual misoprostol versus oxytocin: Results from a randomized non‐inferiority trial among women receiving prophylactic oxytocin

International Journal of Gynecology & Obstetrics (2009)

Jennifer Blum Beverly Winikoff Sheila Raghavan Rasha Dabash Mohamed Ramadan

Medical journal

10.1016/s0020-7292(09)60086-2

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Citations (3)

Mifepristone Followed in 24 Hours to 48 Hours by Misoprostol for Late First-Trimester Abortion

Obstetrics and Gynecology (2007)

Hillary Bracken Nguyen Thi Nhu Ngoc Eric A. Schaff Kurus Coyaji Shubha Ambardekar

In Brief OBJECTIVE: To investigate the efficacy of mifepristone and misoprostol for the termination of pregnancies in the late first trimester. METHODS: This was a prospective study of 321 women seeking termination of pregnancy with gestations from 64 days to 84 days (±3 days) by vaginal ultrasonography. Women were enrolled at three sites: University of Rochester Reproductive Health Program in Rochester, New York; Hung Vuong Hospital in Ho Chi Minh City, Vietnam; and K.E.M. Hospital in Pune, India. Eligible women received 800 mcg of misoprostol vaginally between 24 hours and 48 hours after administration of 200 mg mifepristone. Two additional doses of 400 mcg of misoprostol were administered either orally or vaginally as needed every 3 hours for a maximum of two additional doses (total 1,600 mcg). The primary study outcome measure was complete abortion without surgical intervention. RESULTS: Eighty-nine percent of women who completed the study successfully terminated their pregnancies. Most women were either satisfied (64.8%) or very satisfied (28.6%) with their experience. Ninety-four percent of women reported that they would recommend the procedure to a friend. Most women (90.4%) also agreed they would request a medical abortion if they required another abortion at this gestational age. CONCLUSION: Medical abortion is acceptable and effective in the late first trimester and offers women an acceptable alternative to surgical abortion. LEVEL OF EVIDENCE: II Medical abortion is acceptable and effective for late first-trimester abortion and offers women an alternative to surgical abortion.

Medical abortion

Vacuum aspiration

Products of conception

Incomplete Abortion

10.1097/01.aog.0000259319.18958.76

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Citations (25)

Treatment of post-partum haemorrhage with sublingual misoprostol versus oxytocin in women receiving prophylactic oxytocin: a double-blind, randomised, non-inferiority trial

The Lancet (2010)

Jennifer Blum Beverly Winikoff Sheila Raghavan Rasha Dabash Mohamed Ramadan

Post partum

10.1016/s0140-6736(09)61923-1

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Citations (123)

Outpatient mifepristone–misoprostol medical abortion through 77 days of gestation

Contraception (2016)

Ilana G. Dzuba Erica Chong Curtiss Hannum D Kurbanova E. Steve Lichtenberg

Medical abortion

Abortifacient

Products of conception

Outpatient clinic

10.1016/j.contraception.2016.07.027

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Citations (2)

Results from a study using misoprostol for management of incomplete abortion in Vietnamese hospitals: implications for task shifting

BMC Pregnancy and Childbirth (2013)

Nguyen Thi Nhu Ngoc Tara Shochet Jennifer Blum Pham Thanh Hai Duong Lan Dung

Abstract Background Complications following spontaneous or induced abortion are a major cause of maternal morbidity. To manage these complications, post-abortion care (PAC) services should be readily available and easy to access. Standard PAC treatment includes surgical interventions that are highly effective but require surgical providers and medical centers that have the necessary space and equipment. Misoprostol has been shown to be an effective alternative to surgical evacuation and can be offered by lower level clinicians. This study sought to assess whether 400 mcg sublingual misoprostol could effectively evacuate the uterus after incomplete abortion and to confirm its applicability for use at lower level settings. Methods All women presenting with incomplete abortion at one of three hospitals in Vietnam were enrolled. Providers were not asked to record if the abortion was spontaneous or induced. It is likely that all were spontaneous given the legal status and easy access to abortion services in Vietnam. Participants were given 400 mcg sublingual misoprostol and instructed to hold the pills under their tongue for 30 minutes and then swallow any remaining fragments. They were then asked to return one week later to confirm their clinical status. Study clinicians were instructed to confirm a complete expulsion clinically. All women were asked to complete a questionnaire regarding satisfaction with the treatment. Results Three hundred and two women were enrolled between September 2009 and May 2010. Almost all participants (96.3%) had successful completions using a single dose of 400 mcg misoprostol. The majority of women (87.2%) found the side effects to be tolerable or easily tolerable. Most women (84.3%) were satisfied or very satisfied with the treatment they received; only one was dissatisfied (0.3%). Nine out of ten women would select this method again and recommend it to a friend (91.0% and 90.0%, respectively). Conclusions This study confirms that 400 mcg sublingual misoprostol effectively evacuates the uterus for most women experiencing incomplete abortion. The high levels of satisfaction and side effect tolerability also attest to the ease of use of this method. From these data and given the international consensus around the effectiveness of misoprostol for incomplete abortion care, it seems timely that use of the drug for this indication be widely expanded both throughout Vietnam and wherever access to abortion care is limited. Trial registration ClinicalTrials.gov, NCT00670761

Vietnamese

Incomplete Abortion

10.1186/1471-2393-13-118

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Citations (14)

WHO multicentre randomised trial of misoprostol in the management of the third stage of labour

The Lancet (2001)

A. Metin Gülmezoĝlu José Villar Nguyen Thi Nhu Ngoc Gilda Piaggio Guillermo Carroli

Third stage

10.1016/s0140-6736(01)05835-4

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Citations (341)

36. ASSESSMENT OF PATIENT FAMILY MEMBERS' KNOWLEDGE OF RISK FACTORS AND WARNING SIGNS OF STROKE AT PHU THO GENERAL HOSPITAL IN 2024

Tạp chí Y học Cộng đồng (2024)

Na An Nguyen Thi Nhu Ngoc Hoang Quoc Viet

Objectives: Assessment of Family Members' Knowledge of Risk Factors and Warning Signs of Stroke at the Stroke Center, Phu Tho General Hospital (2024). Methods: Cross-sectional descriptive study. Results: The study conducted on 196 family members of patients at the Stroke Center, Phu Tho General Hospital, revealed that their knowledge of the risk factors for stroke varied. Hypertension (92.3%) was the most commonly recognized risk factor. Other risk factors, such as smoking (62.7%) and lack of physical activity (63.8%), were less well-known. Weakness, paralysis of one side of the body, and dysphasia were the most recognized warning signs of stroke, with 94.9% and 91.3% awareness rates, respectively. Analysis of the correlation between knowledge of stroke risk factors showed that individuals aged ≤ 50 had a 5.53 times higher level of knowledge than those > 50 years old. Those with a profession had a 3.16 times higher level of knowledge than the unemployed, and residents of Viet Tri City had a 1.84 times higher level of knowledge compared to those living elsewhere, differences were statistically significant with p<0.05. Regarding knowledge of stroke warning signs, individuals aged ≤ 50 had 11.68 times better knowledge than those > 50 years old, and residents of Viet Tri City had 2.44 times better knowledge compared to those living elsewhere (p<0.05). Conclusion: Knowledge about stroke risk factors and warning signs varies among family members of patients. The associated demographic characteristics include age ≤ 50 and residence in Viet Tri City.

Stroke

Warning signs

Cross-sectional study

10.52163/yhc.v65i13.1874

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Citations (0)

Reduced dose of mifepristone and home administration of misoprostol in early pregnancy termination

International Journal of Gynecology & Obstetrics (2000)

Nguyen Thi Nhu Ngoc

Medical abortion

Medical journal

10.1016/s0020-7292(00)85236-4