Dalva Trevisan Ferreira

Universidade Estadual de Londrina

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Raimundo Braz‐Filho

State University of Norte Fluminense

Milton Faccione

Universidade Estadual de Londrina

Mário Geraldo de Carvalho

Universidade Federal Rural do Rio de Janeiro

César C. Andrei

Universidade Estadual de Londrina

Terezinha de Jesus Faria

Universidade Estadual de Londrina

Jurandir Pereira Pinto

Universidade Estadual de Londrina

Iuri Bezerra de Barros

Federal Center for Technological Education Celso Suckow da Fonseca

Queli Cristina Fidelis

Universidade Federal do Maranhão

Halha Ostrensky Saridakis

Universidade Estadual de Londrina

Alaı́de Braga de Oliveira

Universidade Federal de Minas Gerais

Cooperative Institutions

Universidade Estadual de Londrina

Universidade de São Paulo

Universidade Federal Rural do Rio de Janeiro

Universidade Estadual de Campinas (UNICAMP)

Universidade Federal de Minas Gerais

Universidade Estadual Paulista (Unesp)

Universidade Tecnológica Federal do Paraná

Universidade Estadual de Maringá

Weatherford College

Universidad Nacional Pedro Ruíz Gallo

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Iridóide glicosilado e derivados fenólicos antifúngicos isolados das raízes de Spathodea campanulata

Semina Ciências Agrárias (2007)

Adriana Pianaro Jurandir Pereira Pinto Dalva Trevisan Ferreira Noemia Kazue Ishikawa Raimundo Braz‐Filho

O estudo químico das cascas das raízes de Spathodea campanulata (Bignoniaceae) conduziu ao isolamento de um irióide glicosilado (ajugol) e dois derivados fenólicos (ácido p -hidroxi-benzóico e p -hidroxi-benzoato de metila). Os compostos foram identificados com base na interpretação dos seus dados espectrais. A atividade biológica destes constituintes foi avaliada contra o fungo Cladosporium herbarum .

10.5433/1679-0359.2007v28n2p251

Cite

Citations (36)

Alcalóides de flores e folhas de Erythrina speciosa Andrews

Química Nova (2007)

Terezinha de Jesus Faria Mariana Carrara Cafêu Gisele Akiyoshi Dalva Trevisan Ferreira Olívio Fernandes Galão

LEAVES OF Erythrina speciosa ANDREWS.In vitro bioassays with leave extracts of Erythrina speciosa showed promising activity against Trypanosoma cruzi.From the flowers of E. speciosa two alkaloids were isolated: erysotrine and erythartine.The leaves furnished one alkaloid, nororientaline.The structures were determined on the basis of spectroscopic evidence.This is the first report about the investigation of alkaloids in flowers and leaves of this species, as well the first report of nororientaline occurrence in this plant.

Erythrina

10.1590/s0100-40422007000300004

Cite

Citations (15)

Antimicrobial activity and chemical investigation of Brazilian Drosera

Memórias do Instituto Oswaldo Cruz (2004)

Dalva Trevisan Ferreira César C. Andrei Halha Ostrensky Saridakis Terezinha de Jesus Faria Elisângela Vinhato

The antimicrobial activity of three different extracts (hexanic, ethyl acetate, methanol) obtained from Brazilian Drosera species (D. communis, D. montana var. montana, D. brevifolia, D. villosa var. graomogolensis, D. villosa var. villosa, Drosera sp. 1, and Drosera sp. 2 ) were tested against Staphylococcus aureus (ATCC 25923), Enterococcus faecium (ATCC23212), Pseudomonas aeruginosa (ATCC27853), Escherichia coli (ATCC11229), Salmonella choleraesuis (ATCC10708), Klebsiella pneumoniae (ATCC13883), and Candida albicans (a human isolate). Better antimicrobial activity was observed with D. communis and D. montana var. montana ethyl acetate extracts. Phytochemical analyses from D. communis, D. montana var. montana and D. brevifolia yielded 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin); long chain aliphatic hydrocarbons were isolated from D. communis and from D. villosa var. villosa, a mixture of long chain aliphatic alcohols and carboxylic acids, was isolated from D. communis and 3b-O-acetylaleuritolic acid from D. villosa var. villosa.

Villosa

10.1590/s0074-02762004000700016

Cite

Citations (25)

Evaluation of extracts from Coccoloba mollis using the Salmonella/microsome system and in vivo tests

Genetics and Molecular Biology (2010)

Marcela Stefanini Ferreira Tsuboy Juliana Cristina Marcarini Dalva Trevisan Ferreira Elisa Raquel Anastácio Ferraz Farah Maria Drumond Chequer

The common everyday use of medicinal plants is an ancient, and still very widespread practice, whereby the need for studies on their possible toxicity and mutagenic properties. The species Coccoloba mollis has been much used in phytotherapy, mainly in cases involving loss of memory and stress. In order to investigate its genotoxic and mutagenic potential, ethanolic extracts from the leaves and roots underwent Salmonella/microsome assaying (TA98 and TA100 strains, with and without exogenous metabolism - S9), besides comet and micronucleus tests in vivo.There was no significant increase in the number of revertants/plate of Salmonella strains in any of the analyzed root-extract concentrations, although the extract itself was extremely toxic to the Salmonella TA98 strain in the tests carried out with S9 (doses varying from 0.005 to 0.5 μg/plate). On the other hand, the leaf-extract induced mutations in the TA98 strain in the absence of S9 in the highest concentration evaluated, although at very low mutagenic potency (0.004 rev/ μg). Furthermore, there was no statistically significant increase in the number of comets and micronuclei, in treatments involving Swiss mice. It was obvious that extracts of Coccoloba mollis, under the described experimental conditions, are not mutagenic.

10.1590/s1415-47572010005000062

Cite

Citations (7)

New Alkaloid from Aspidosperma Polyneuron Roots

Natural Product Communications (2008)

Tatiane Alves dos Santos Dalva Trevisan Ferreira Jurandir Pereira Pinto Milton Faccione Raimundo Braz‐Filho

The roots of Aspidosperma polyneuron, family Apocynaceae, were subjected to chemical and biological investigations. From an ethanolic extract of the roots, the new alkaloid 2,7-dihydroxyquebrachamine (1) was isolated. The structure was established mainly from 1D and 2D NMR spectroscopic and mass spectrometric data. The 1D and 2D NMR spectra were also used to assign all the 1 H and 13 C chemical shifts of this alkaloid. Artemia salina was used for a preliminary investigation of biological activity.

Apocynaceae

Aspidosperma

Artemia salina

Chemical structure

10.1177/1934578x0800300212

Cite

Citations (1)

Cytotoxicity, genotoxicity and mechanism of action (via gene expression analysis) of the indole alkaloid aspidospermine (antiparasitic) extracted from Aspidosperma polyneuron in HepG2 cells

Cytotechnology (2015)

Giuliana Castello Coatti Juliana Cristina Marcarini Daniele Sartori Queli Cristina Fidelis Dalva Trevisan Ferreira

10.1007/s10616-015-9874-9

Cite

Citations (11)

Opiate, Opioid analgesics and antagonists

DOAJ (DOAJ: Directory of Open Access Journals) (2005)

Milton Faccione Dalva Trevisan Ferreira

Opiate

Narcotic antagonists

Source

Cite

Citations (0)

Free radical scavenging activity of Pfaffia glomerata (Spreng.) Pederson (Amaranthaceae)

Indian Journal of Pharmacology (2005)

R. B. Freire Dalva Trevisan Ferreira Mário M. Freire José Daniel K. Z. Alves

OBJECTIVE : To evaluate the free radical scavenging and cytotoxic activities of the butanolic (BuOH) extract, methanolic (MeOH) extract and 20-hydroxyecdysone extracted from the roots of Pfaffia glomerata .
MATERIALS AND METHODS : Pfaffia glomerata roots were collected, powdered and extracted with methanol by maceration at room temperature. The extract was concentrated under vacuum, yielding a residue, followed by a butanol extraction. The 20-hydroxyecdysone (EC) was obtained by chromatographic separation of the BuOH fraction. An amount of 10 mg of each dry extract and EC was dissolved in 0.1% dimethyl sulphoxide-phosphate-buffered-saline solution (DMSO-PBS) and screened for their capabilities on scavenging thiobarbiturate reactive substances (TBARS). The antioxidant activity of each extract was determined in vitro by measuring malonyldialdehyde (MDA) and 4-hydroxynonenal (4-HNE) in erythrocyte ghosts treated with ferric-ascorbate. The investigation has also included the cytotoxicity measurement by Trypan blue exclusion test and tetrazolium reduction assay in mice peritoneal macrophages.
RESULTS : The free radical scavenging activity of EC was higher than that present in the BuOH fraction. The MeOH extract showed a remarkable pro-oxidant activity. The EC-free radical reaction-inhibition was almost twice of that of the control a-Tocopherol (aT). The Trypan blue exclusion assay confirmed toxicity of the MeOH extract, whose lethality surpassed 80% of the treated macrophages after 1 h of 0.01 mg exposure per 106 cells.
CONCLUSIONS : The present study shows the antioxidant effect of the Brazilian Ginseng. The scavenging effect was evidenced for EC as well the BuOH fraction. The MeOH extract showed cytotoxicity on mice peritoneal macrophages. Such toxicity is probably due to ginsenosides present in this latter fraction and warrants further toxicological evaluation of the Brazilian Ginseng roots.

Trypan blue

TBARS

Maceration (sewage)

Soxhlet extractor

Amaranthaceae

10.4103/0253-7613.16215

Cite

Citations (14)

Differentiation of Species of the Baccharis Genus by HPLC and Chemometric Methods

Analytical Sciences (2003)

Audrey Alesandra Stinghen Garcia Lonni Ieda Spacino Scarmínio Lucas M.C. Silva Dalva Trevisan Ferreira

Baccharis

10.2116/analsci.19.1013

Cite

Citations (19)

Constituintes químicos das raízes de Pyrostegia Venusta e considerações sobre a sua importância medicinal

Química Nova (2000)

Dalva Trevisan Ferreira Paulo Sérgio M. Alvares Peter J. Houghton Raimundo Braz‐Filho

ITS MEDICINAL IMPORTANCE.This paper describes the chemical constituents isolated from roots of Pyrostegia venusta.From ethanol extract of the roots allantoin, β-sitosterol, 3β-O-β-Dglupyranosylsitosterol and hesperedin were isolated.The structures of these natural products were identified on the basis of spectral data, including 2D NMR of the peracetyl derivative of hesperidin.

10.1590/s0100-40422000000100010

Cite

Citations (42)