Noritoshi Takeichi

Hokkaido University

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Masayoshi Kajiyama

Kushiro Rosai Hospital

Nobuyuki Fujita

Fujita Health University

Tsunenori Nakakoshi

Harvard University

Kazuo Miyasaka

Hokkaido University

Michio Mori

Sapporo City General Hospital

Kang Jong-Hon

Hokkaido University

Hiroshi Kobayashi

National Center for Global Health and Medicine

Kimimaro Dempo

Sapporo Medical University

Michihiro C. Yoshida

Nagoya City University

Nobuaki Nakayama

Saitama Medical University

Cooperative Institutions

Hokkaido University

Sapporo University

Hokkaido University Hospital

Sapporo Medical University

Jikei University School of Medicine

The University of Tokyo

Kushiro Rosai Hospital

Fujita Health University

Fujita Health University Hospital

Barro Colorado Island

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SPONTANEOUS HEPATITIS IN LONG‐EVANS RATS: A Potential Animal Model for Fulminant Hepatitis in Man

Acta Pathologica Japonica (1988)

Noritoshi Takeichi Hiroshi Kobayashi Michihiro C. Yoshida Motomichi Sasaki Kimimaro Dempo

Spontaneous hepatitis associated with severe jaundice occurred in 90% of an inbred strain of Long‐Evans rats. The rapidly progressive syndrome was characterized by abrupt onset, hyperbilirubinemia and increased serum levels of glutamic oxaloacetic transaminase and glutamic pyruvic transaminase, associated with massive and multifocal necrosis of the liver. This strain should provide a useful animal model for analysis of the pathogenesis of fulminant hepatitis in humans. ACTA PATHOL JPN 38: 1369–1375, 1988.

Fulminant hepatitis

Fulminant

Transaminase

Pathogenesis

10.1111/j.1440-1827.1988.tb01080.x

Cite

Citations (52)

Quantitative analyses of correlations of signal intensity on T1-weighted images and T1 relaxation time with copper concentration in the rat liver

Academic Radiology (1996)

Tsunenori Nakakoshi Masayoshi Kajiyama Nobuyuki Fujita Kang Jong-Hon Noritoshi Takeichi

Intensity

10.1016/s1076-6332(96)80330-8