Rita Carolina Pozzer Krumenauer

Universidade Federal de Ciências da Saúde de Porto Alegre

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José Faibes Lubianca Neto

Universidade Federal de Ciências da Saúde de Porto Alegre

Sérgio L. Amantéa

Hospital Moinhos de Vento

Vanessa F. Marta

Hospital de Clínicas de Porto Alegre

Luiz R. Braun Filho

Universidade Federal de Ciências da Saúde de Porto Alegre

Adriana Becker

Hospital Nossa Senhora da Conceição

Luciano S. Vitola

Hospital de Clínicas de Porto Alegre

Luciana Pimentel Oppermann

Universidade Federal de Ciências da Saúde de Porto Alegre

Gerson Schulz Maahs

Pontifícia Universidade Católica do Rio Grande do Sul

Cláudia Schweiger

Hospital de Clínicas de Porto Alegre

Rosane Reginato

Universidade Federal de Ciências da Saúde de Porto Alegre

Cooperative Institutions

Universidade Federal do Rio Grande do Sul

Hospital de Clínicas de Porto Alegre

Universidade Federal de Ciências da Saúde de Porto Alegre

Santa Casa Hospital

Pontifícia Universidade Católica do Rio Grande do Sul

Santa Casa de Misericórdia de Marília

Hospital Nossa Senhora da Conceição

Fundação Faculdade de Medicina

Boston Children's Hospital

United Food and Commercial Workers

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Anterior laryngeal membrane and 22q11 deletion syndrome

Brazilian Journal of Otorhinolaryngology (2011)

Rafael Fabiano Machado Rosa Rosana Cardoso Manique Rosa Rita Carolina Pozzer Krumenauer Marileila Varella‐Garcia Giorgio Adriano Paskulin

Doctoral degree in genetics and molecular biology, medical geneticist at UFCSPA/CHSCPA. Professor in the Clinical Genetics Discipline and the Graduate Program on Pathology, UFCSPA. Cytogeneticist in charge of the Cytogenetics Laboratory of the UFCSPA, Brazil.Santo Antonio Child Hospital (Hospital da Crianca Santo Antonio - HCSA), Porto Alegre Health Science Federal University (Universidade Federal de Ciencias da Saude de Porto Alegre - UFCSPA), Porto Alegre Holy House Hospital Complex (Complexo Hospitalar Santa Casa de Porto Alegre - CHSCPA), and University of Colorado.Send correspondence to: Prof. Dr. Giorgio Adriano Paskulin, Rua Sarmento Leite, 245/403, Bairro Centro, Porto Alegre - RS, Brazil.Phone. (0xx51) 3303-8771 - Fax: (0xx51)33038810University of Colorado (US) and CAPES (Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior) (Brazil).Paper submitted to the BJORL-SGP (Publishing Management System – Brazilian Journal of Otorhinolaryngology) on July 15, 2010;and accepted on October 10, 2010. cod. 7209

Geneticist

10.1590/s1808-86942011000400024

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Citations (6)

Complicacoes urologicas graves apos radioterapia pelvica por neoplasia de colo uterino

Revista da AMRIGS (1999)

Rita Carolina Pozzer Krumenauer Carolina Blaya Giovani Thomaz Pioner Dante Sica

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Uso da mistura gasosa de hélio e oxigênio (Heliox®) no tratamento da doença respiratória obstrutiva da via aérea inferior em serviço de emergência pediátrica

Jornal de Pediatria (2010)

Luiz R. Braun Filho Sérgio L. Amantéa Adriana Becker Luciano S. Vitola Vanessa F. Marta

OBJETIVO: Determinar se a utilização de salbutamol, em uma mistura de hélio-oxigênio (80:20), modifica a evolução e o risco de internação em pacientes pediátricos. MÉTODOS: Delineado estudo de coorte controlada que incluiu pacientes de 2 meses a 12 anos de idade, com diagnósticos de crise de asma ou bronquiolite viral. Intensidades caracterizadas de moderada a grave, aferidas através de escore clínico (pulmonary index, PI) para doença obstrutiva. Foram considerados elegíveis escores > 8. Vinte pacientes constituíram o grupo Heliox® e 40 o grupo Oxigênio. Os pacientes receberam sequencialmente, em intervalos de 20 min, até completar seis nebulizações (período de 2 h): salbutamol 0,15 mg/kg/dose (máximo 5 mg). A droga utilizou como veículo gerador do aerossol a mistura de Heliox® (80:20) ou oxigênio a 100%. Os pacientes com diagnóstico de crise aguda de asma receberam, adicionalmente, prednisolona (2 mg/kg) via oral. RESULTADOS: Onze pacientes do grupo Heliox® permaneceram necessitando de tratamento na 6ª h de atendimento, enquanto que no grupo que recebia nebulização veiculada em oxigênio, esse número foi de 38 (p = 0,034). Na 12ª h, 7 pacientes do grupo Heliox® permaneciam em observação, enquanto no grupo Oxigênio foram 27 (p = 0,02). Diferenças quanto à necessidade de suplementação de oxigênio foram observadas apenas na 6ª h de tratamento (p = 0,02). CONCLUSÕES: Heliox® (80:20), para administração de salbutamol, é efetivo no tratamento da doença obstrutiva infantil que apresente resposta à terapêutica broncodilatadora. Comparado à técnica usual de nebulização, está associado à menor permanência em sala de observação após 6 h de tratamento.

Heliox

Non-blocking I/O

10.1590/s0021-75572010000500012

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Citations (8)

Hipocondria: caracteristicas e manejo. Uma revisao

Bruno Scheidt Rita Carolina Pozzer Krumenauer Rodigo Vieira

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in the treatment of obstructive lower airway disease in a pediatric emergency department Uso da mistura gasosa de hélio e oxigênio (Heliox ® ) no tratamento da doença respiratória obstrutiva da via aérea inferior em serviço de emergência pediátrica

Luiz R. Braun Filho Sérgio L. Amantéa Adriana Becker Luciano S. Vitola Vanessa F. Marta

Abstract Objective: To determine whether the use of salbutamol, in a helium-oxygen mixture (80:20), can modify outcome and risk of hospitalization of pediatric patients. Methods: A controlled cohort study including patients aged 2 months to 12 years with diagnoses of asthmatic crisis or viral bronchiolitis. Intensity was characterized from moderate to severe, as measured by clinical score (pulmonary index, PI) for obstructive disease. Scores > 8 were considered eligible. The Heliox ® group was composed of 20 patients and the Oxygen group of 40 patients. Patients received sequentially, at 20-min intervals, until six nebulization cycles were completed (2-h period): salbutamol 0.15 mg/kg/dose (maximum 5 mg). The nebulized drug was driven either by Heliox ® mixture (80:20) or 100% oxygen. Patients diagnosed with acute asthmatic crisis received, additionally, prednisolone (2 mg/kg) orally. Results: Eleven patients in the Heliox ® group still required treatment at 6 h, against 38 patients in the group receiving oxygen-driven nebulization (p = 0.034). At 12 h, 7 patients in the Heliox

Heliox

Acute Bronchiolitis

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Determinants of successful tracheostomy decannulation in children: a multicentric cohort study

The Journal of Laryngology & Otology (2020)

Cláudia Schweiger Denise Manica José Faibes Lubianca Neto Leo Sekine Rita Carolina Pozzer Krumenauer

Abstract Background Determining prognostic factors for the probability of tracheostomy decannulation is key to an adequate therapeutic plan. Methods A retrospective cohort study of 160 paediatric patients undergoing tracheostomy was conducted. Associations between different parameters and eventual tracheostomy decannulation were assessed. Results Mean follow-up duration was 27.8 months (interquartile range = 25.5–30.2 months). Median age at tracheostomy was 6.96 months (interquartile range = 3.37–29.42 months), with median tracheostomy maintenance of 14.5 months (interquartile range = 3.7–21.5 months). The overall tracheostomy decannulation rate was 22.5 per cent. Factors associated with a higher probability of tracheostomy decannulation included age at tracheostomy (hazard ratio = 1.11, 95 per cent confidence interval = 1.03–1.18) and post-intubation laryngitis as an indication for tracheostomy (hazard ratio = 2.25, 95 per cent confidence interval = 1.09–4.62). Neurological (hazard ratio = 0.30, 95 per cent confidence interval = 0.12–0.80) and pulmonary (hazard ratio = 0.41, 95 per cent confidence interval = 0.18–0.91) co-morbidities were negatively associated with tracheostomy decannulation. The probability of tracheostomy decannulation decreased significantly with increasing numbers of co-morbidities ( p < 0.001). Conclusion Age, post-intubation laryngitis, and number and type of co-morbidities influence tracheostomy decannulation rate in the paediatric population.

Interquartile range

Tracheotomy

10.1017/s0022215119002573

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Citations (15)

Pressure gradient and inspiratory times required for valve opening of various holding chambers

Allergy and Asthma Proceedings (2011)

Rosane Reginato Sérgio L. Amantéa Rita Carolina Pozzer Krumenauer

This study was designed to determine whether infants generate sufficient inspiratory pressure gradient to open the unidirectional valve of various commercially available holding chambers, as well as the time required to reach this gradient. A prospective, cross-sectional study was performed of 80 healthy infants (aged 1-24 months) seen in the childcare outpatient clinic of a pediatric hospital, from October to December of 2007. Using the same inhalation technique recommended for treatment of respiratory diseases and asthma in this age group, four holding chambers were analyzed: Flumax Baby, AlergoChamber, LuftChamber, and ACE (n = 20 infants per analysis group). The variables measured were gradient of inspiratory pressure and time for the valve to open. The holding chambers did not differ in gradient of inspiratory pressure (p = 0.382) or time to open the valve (p = 0.199). Fifteen of 80 infants were not able to generate sufficient inspiratory pressure to open the valve (1 using AlergoChamber, 5 using Flumax Baby, 6 using ACE, and 3 using LuftChamber), with no significant differences between devices. The holding chambers were similar regarding pressure gradient and time required to open the valve. The fact that 19% of the sample was unable to open the valve suggests that it would be useful to determine the ability of small children (<24 months of age) to use holding chambers before prescribing them.

Pressure gradient

Outpatient clinic

Peak inspiratory pressure

10.2500/aap.2011.32.3421

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Citations (4)

Revealing the needs of children with tracheostomies

European Annals of Otorhinolaryngology Head and Neck Diseases (2018)

Rebecca Maunsell Melissa Avelino J. Caixeta Alves Graziela Semenzati José Faibes Lubianca Neto

Interquartile range

Laryngomalacia

Tracheotomy

Laryngitis

Medical record

10.1016/j.anorl.2018.07.007

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Citations (25)

COVID-19 in otolaryngologists: a cross-sectional multicenter study

Figshare (2023)

Fabrício Scapini José Faibes Lubianca Neto Roberto Dihl Angeli Rita Carolina Pozzer Krumenauer Ingrid Wendland Santanna

Abstract Introduction: The nose and throat are areas of high viral load, which could place otolaryngologists at an even higher risk for COVID-19 than other health-care workers. Objective: To investigate the prevalence of antibodies against SARS-CoV-2 in otorhinolaryngologists in southern Brazil, its relationship to demographic data, professional practice and reported symptoms of COVID-19, and compare it with official data on other health-care workers of the state and the general population in the same period. Methods: In this cross-sectional multicenter study, otolaryngologists actively practicing officially registered in Rio Grande do Sul were screened for IgM and IgG antibodies against SARS-CoV-2 from August 1 to September 15, 2020. A questionnaire was also applied. Results: We screened 358 (80.1%) of 447 actively practicing otolaryngologists (195 [54.5%] male; mean [SD] age, 47.77 [13.57] years; range, 26-84 years). Twenty-three were positive for IgM and/or IgG (6.4%). This result was significantly associated with reports of infected household contacts (19/315 negatives and 8/23 positives; p<0.001). From 23 seropositive participants, 14 were asymptomatic (60.9%; p< 0.001). There were no significant associations between seroconversion and age, sex, number of patient appointments and surgical procedures, workplace (hospital or private practice), patients with or without respiratory symptoms, or level of personal protective equipment used. The rate of COVID-19 in all health-care workers in the state was 7.69% at the end of the same period. Data from state government seroprevalence was 5.26 (risk ratio [RR]; 95% CI 3.27–8.45) and 4.66 (RR; 95% CI 2.93–7.43) times higher in otolaryngologists than in the general population in August and September, respectively. Conclusion: Otolaryngologists had a higher seroconversion rate than the general population. Using personal protective equipment, the level of occupational exposure did not result in higher rates of infection than other health-care workers, but the presence of infected household contacts was associated with higher rates of seroconversion.

Cross-sectional study

2019-20 coronavirus outbreak

Pandemic

10.6084/m9.figshare.21936738

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Achados clínicos e endoscópicos em crianças com estridor

Revista Brasileira de Otorrinolaringologia (2002)

José Faibes Lubianca Neto Gilberto Bueno Fischer Fernanda Peduzzi L. Humberto Rita Carolina Pozzer Krumenauer

Introdução: As anomalias da via aérea freqüentemente se apresentam com estridor. A sua principal causa em recém-nascidos e lactentes são as alterações congênitas da laringe. O diagnóstico etiológico específico pode ser realizado com a fibronasolaringobroncoscopia, a qual é fundamental para o manejo adequado dessas crianças. Forma de estudo: prospectivo clínico de delineamento transversal de análise descritiva. Objetivo: Descrever as principais causas e achados clínicos associados ao estridor das crianças que se apresentam em nosso hospital. Material e Método: Realizou-se um estudo prospectivo, no período de março de 2000 a abril de 2001, que avaliou todas as crianças encaminhadas ao Serviço de Otorrinolaringologia Pediátrica do Hospital da Criança Santo Antônio, cujo critério de inclusão foi a presença de estridor. Os pacientes foram então avaliados segundo protocolo definido a priori, que incluía, além de perguntas sobre história, exame físico e comorbidades associadas, o exame fibronasolaringobroncoscópico padronizado. Resultados: Foram avaliadas 125 crianças com estridor: 69 masculinos e 56 femininos. A idade média de apresentação foi de 19 meses. A maior parte dos pacientes avaliados veio da unidade de tratamento intensivo. Foram encontradas comorbidades em quase todos os casos, sendo a intubação prolongada a mais comum (n=36, 28,8%). Os diagnósticos mais freqüentes foram laringomalácia em 51 (40,8%) pacientes e estenose subglótica em 22 (17,6%). Conclusões: Mesmo que se tenha avaliado pacientes mais selecionados do que as grandes séries mundiais, as anomalias congênitas da laringe também foram a maior causa de estridor em nossa casuística. Em alguns casos com história de intubação prolongada foi difícil diferenciar a estenose subglótica congênita da adquirida. A presença de comorbidades é freqüente e pode auxiliar na seleção dos pacientes que necessitam de exame endoscópico.

10.1590/s0034-72992002000300004

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Citations (7)