CP Lohmann

Klinikum rechts der Isar

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C. Winkler von Mohrenfels

Ludwig-Maximilians-Universität München

Mathias Maier

Technical University of Munich

B. Gabler

University of Regensburg

Wolfgang Herrmann

University of Regensburg

Nikolaus Feucht

Technical University of Munich

V.–P. Gabel

University of Regensburg

John Marshall

University College London

David O’Brart

St Thomas' Hospital

Karsten Hufendiek

Medizinische Hochschule Hannover

M. Maier

Klinik und Poliklinik für Augenheilkunde Universitätsklinikum Regensburg

Cooperative Institutions

Klinikum rechts der Isar

Technical University of Munich

Klinik und Poliklinik für Augenheilkunde Universitätsklinikum Regensburg

University of Regensburg

University Hospital Regensburg

Ludwig-Maximilians-Universität München

University College London

St Thomas' Hospital

Universitäts-Augenklinik Bonn

Friedrich-Alexander-Universität Erlangen-Nürnberg

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Excimer Laser Phototherapeutic Keratectomy for Recurrent Erosions: A Clinical Study

Ophthalmic surgery, lasers & imaging retina (1996)

CP Lohmann H. Sachs N. Justin Marshall V.–P. Gabel

* BACKGROUND AND OBJECTIVE: Recurrent corneal erosion is a common corneal disease. It may be difficult to treat, with a number of patients suffering persistent symptoms despite having had conventional therapy. The aim of this study was to evaluate the usefulness of the excimer laser for the treatment of recurrent corneal erosions. * PATIENTS AND METHODS: The authors studied 31 eyes of 24 patients who underwent excimer laser phototherapeutic keratectomy (PTK) for recurrent corneal erosion. Three eyes were treated during an acute episode of recurrent erosion. The remaining eyes were treated during a symptom-free interval. The affected area of epithelium was removed and a 25 pulse ablation was performed to Bowman's membrane. * RESULTS: In 30 eyes there was a marked improvement in symptoms postoperatively, with no recurrences. However, 1 eye had one recurrent episode 2 weeks after PTK. Postoperatively, refraction and corneal topography were unaltered in all cases. * CONCLUSIONS: Excimer laser PTK appears to be a safe and promising procedure for cases of recurrent corneal erosion refractory to medical treatment. [Ophthalmic Surg Lasers 1996;27:768-772.]

Phototherapeutic keratectomy

Excimer

Refractory (planetary science)

10.3928/1542-8877-19960901-07

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Citations (40)

Okulärer Therapieverlauf retinaler Hämangioblastome bei von-Hippel-Lindau-Syndrom (VHL)

Klinische Monatsblätter für Augenheilkunde (2011)

C Zorn M. Zorn E. M. Glaser M. Maier CP Lohmann

Eine 27-jährige, ophthalmologisch asymptomatische, Patientin wurde uns erstmals im März 2007 zur Mitbeurteilung von der Urologie bei Erstdiagnose eines von-Hippel-Lindau-Syndroms vorgestellt.

Von Hippel–Lindau disease

10.1055/s-0029-1245736

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Citations (0)

Cellular and nerve regeneration within a biosynthetic extracellular matrix for corneal transplantation

American Journal of Ophthalmology (2004)

F. Li D. J. Carlsson CP Lohmann Erik J. Suuronen Sandy G. Vascotto

Decellularization

10.1016/j.ajo.2004.06.049

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Citations (7)

Tear Film Function and Corneal Sensation After LASEK for the Correction of Myopia

Investigative Ophthalmology & Visual Science (2005)

Wolfgang Herrmann CP Lohmann Chirag P. Shah Karsten Hufendiek C. Winkler von Mohrenfels

Sensation

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Citations (2)

Visusminderung nach Pipamperon-Therapie

Der Ophthalmologe (2011)

D. Loos Peter H Kook J. Huber C Zorn CP Lohmann

10.1007/s00347-011-2349-2

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Citations (0)

[Laser epithelial keratomileusis (LASEK) for treatment of myopia up to -6.0 D. Results from 108 eyes after 12 months].

Der Ophthalmologe (2004)

B. Gabler C. Winkler von Mohrenfels Wolfgang Herrmann CP Lohmann

Emmetropia

Astigmatism

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Treatment of band keratopathy by excimer laser phototherapeutic keratectomy: surgical techniques and long term follow up.

British Journal of Ophthalmology (1993)

David O’Brart David Gartry CP Lohmann A. Patmore M G Kerr Muir

A series of 122 eyes with band keratopathy was treated by excimer laser phototherapeutic keratectomy (PTK), with a mean follow up of over 12.3 months (range 3 to 60 months). A single photoablation zone was used to remove the opacity over the visual axis in smooth surfaced band deposition. In eyes with reduced vision, an improvement was reported in 88% and in a series of 66 eyes mean Snellen visual acuity increased significantly (p < 0.05, t = 2.27). A reduction in glare was reported in 88% and in a series of 17 patients, visual contrast sensitivity (p < 0.01) and measurements of disability glare (p < 0.01) improved postoperatively. The mean hyperopic shift in 32 eyes at 6 months was 1.4 D (range 0-4.25 D). Multiple overlapping ablation zones, with mechanical debulking of large calcium plaques, were used to smooth the irregular corneal surface in eyes with rough bands. Ocular discomfort was improved in 95%. Band keratopathy recurred in nine eyes (8%) within 2 to 30 months (mean 12 months) of surgery, with silicone oil responsible in five eyes. Reablation was necessary in three eyes and performed successfully in all cases. Excimer laser PTK is a safe and effective outpatient treatment for band keratopathy.

Phototherapeutic keratectomy

Photoablation

Excimer

10.1136/bjo.77.11.702

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Citations (92)

Combined 23‐gauge sutureless pars plana vitrectomy (ppV), injection of recombined tissue plasminogen activator (rtPA), expansile gas and bevacizumab treating acute subretinal haemorrhage (SRH) in exudative AMD

Acta Ophthalmologica (2009)

Mathias Maier C. Perz Nikolaus Feucht Julia Konrad C. Winkler von Mohrenfels

Abstract Purpose To evaluate the effect of 23‐gauge core ppV with consecutive intravitreal injection of rtPA, gas and bevacizumab for the displacement of SRH in patients with exudative age‐related macular degeneration (AMD). Methods The retrospective, non‐randomized case study included 15 eyes of 15 patients aged 74 to 89 with SRH resulting from exsudative AMD. Each patient was treated with 23‐gauge ppV and injection of 0.05 ml rtPA (50 μg), 0.3 ml of sulphur hexafluoride (SF6) gas and 0.05 ml bevacizumab (1.25 mg). Visual acuity (VA), lesion size measured by fluorescein angiography (FA) and retinal thickness as determined by optical coherence tomography (OCT) were evaluated pretreatment as well as 1, 3 and 6 months postoperatively. Results The mean visual acuity pretreatment was 20/400. The figure remained constant until month 3 postoperatively. At 6 months, the mean VA had improved to 20/200. No patient had reading ability before treatment. 1 month postoperatively reading VA was achieved in 6 %, rising to 27% at 6 months. There was a reduction in retinal thickness in 8 patients measured by OCT. FA showed a reduction of lesion size in 10 out of 15 patients. Conclusion The combined application of rtPA, gas and bevacizumab via 23‐gauge PPV for the treatment of SRH secondary to exudative AMD appears to be a safe and effective method. In our study, the combined treatment including the injection of bevacizumab enabled 27 % of patients to achieve reading ability at 6 months postoperatively.

10.1111/j.1755-3768.2009.3317.x

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Laser epithelial keratomileusis (LASEK): Correction of moderate (-6,0 D) and higher (-12,0 D) myopia - 6 months clinical results

Investigative Ophthalmology & Visual Science (2002)

B. Gabler C. Winkler von Mohrenfels CP Lohmann

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'Haze' in photorefractive keratectomy : Its origins and consequences

CP Lohmann David Gartry M Kerr Muir George T. Timberlake FW Fitzke

A marginal loss of corneal transparency or 'haze' is a phenomenon experienced after photorefractive keratectomy using excimer lasers (193 nm). In this study, the authors present a review of the current literature relating to this phenomenon and illustrate this with an example of pathology from a two-week postoperative human eye. They also report the functional implications of postoperative changes in corneal transparency using psychophysical tests measuring visual acuity at different contrast levels (100, 20 and 5%). The data were collected from 103 patients at various postoperative intervals with a maximum follow-up time of one year. At 100% contrast, the authors found only slight disturbances in the first six to eight weeks postoperatively. At 20% contrast most patients had a decrease of visual acuity in the first six weeks but all returned to the normal range by 14 weeks postoperatively. At the 5% level, all patients showed significant disturbances in the first 12 to 14 postoperative weeks, but again most were back in the normal range after this period. However, some patients showed a second wave of decrease of visual performance at the low contrast level commencing at four months, peaking at nine months, and thereafter again regressing to the normal preoperative level. This second wave of visual disturbance may correlate with cellular responses subsequent to cessation of steroid therapy at three months.

Excimer

Haze

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Citations (119)