[54747-02-3] C14H14CuLi (MW 252.77) InChI = 1S/2C7H7.Cu.Li/c2*1-7-5-3-2-4-6-7;;/h2*3-6H,1H3;; InChIKey = WAWPKGUVDOWBKD-UHFFFAOYSA-N (tolylating reagent which undergoes conjugate addition reactions,2 addition reactions to pyrylium3, 4 and pyridinium salts,5 and substitution reactions6, 7) Physical Data: a clear yellow solution results from the reaction of a 1∶1 mixture of (p-MeC6H4)4Cu4 and p-MeC6H4Li in Et2O, from which dimeric and tetrameric species have been isolated. Cryoscopic molecular weight determinations in C6H6 support a (p-MeC6H4)4Cu2Li2·2OEt2 composition. This complex is stable up to 135 °C. 1H NMR (C6D6) δ = 0.64 (t, OCMe), 2.08 (s, p-Me), 2.72 (q, OCH2), 7.0 (d, H-3), 8.20 (d, H-2, J2,3 = 7.5 Hz). If prepared in C6H6, an unsolvated complex is formed which decomposes at ∼110 °C.1c,8 Solubility: sol Et2O, THF. Preparative Methods: prepared in situ from CuI salts (Copper(I) Iodide,5, 6 Copper(I) Bromide9) under an inert atmosphere of N2 or argon in Et2O, THF, or C6H6.1c,8 See Lithium Dimethylcuprate for purification of CuI salts. Handling, Storage, and Precautions: extremely sensitive to moisture and oxygen; ignites spontaneously in air. Use in a fume hood.
The synthesis and variable-temperature n.m.r. spectra of di-µ-chloro-bis-[(α,1,2-trihapto-3,3,5,5-tetramethylmethylenecyclohexane)palladium(II)] are described. The spectra give convincing evidence for the σ–π mechanism of exchange in dynamic π-allylic palladium systems and illustrate the general utility of 3,3,5,5-tetramethylmethylenecyclohexane as a ligand for the investigation of the dynamic stereochemistry of olefin and π-allylic metal systems.
[33462-38-3] C6H10CuLi (MW 152.65) InChI = 1S/2C3H5.Cu.Li/c2*1-3-2;;/h2*1,3H,2H3;; InChIKey = NWXANJCJLHDMKM-UHFFFAOYSA-N (propenylating reagent; undergoes conjugate addition reactions,2-4 1,2-addition reactions to aldehydes,5, 6 substitution reactions with alkyl7 and vinyl substrates,8 and oxidative dimerization9) Physical Data: colorless solution in Et2O with CuI;7 ink-blue color with CuI·P(OMe)3.4 Solubility: sol Et2O, THF. Preparative Methods: prepared in situ from CuI salts (Copper(I) Iodide)7 or complexes (Copper(I) Iodide–Tributylphosphine5, 9 and Copper(I) Iodide–Trimethyl Phosphite4) in Et2O or THF at −78 °C under argon1c by the addition of trans-1-propenyllithium.7 See Lithium Dimethylcuprate for purification of CuI salts. Handling, Storage, and Precautions: air- and moisture-sensitive; use in a fume hood.
Abstract Die Stereochemie der Cyanid‐Addition an das Keton (Ia), die zu dem gaschromatographisch trennbaren trans‐cis‐Gemisch der Cyano‐Verbindungen (IIa) und (IIIa) fuhrt, schließt einen axialen Angriff des Nucleophils ein.
Introduction In recent years, the American College of Rheumatology (ACR) has focused increasingly on the development, review, dissemination, and implementation of quality measures. To help position rheumatology providers as the leading force in defining the quality of rheumatology care, the ACR convened a Quality Measures White Paper Development Workgroup. This diverse workgroup’s charge included synthesizing the information most relevant to the ACR membership regarding quality measurement. As described in this manuscript, the workgroup ultimately participated in a consensus development initiative to craft a set of criteria for quality measures submitted to the ACR for approval. The criteria are intended to guide measure developers and discourage adoption of subpar measures. This White Paper is written for rheumatologists interested in quality measurement, groups undertaking quality measure development, and policy makers. It is organized into the following main sections: a brief introduction provides context and describes the ACR’s national role and positions; section 1 outlines quality measure domains and reviews measure attributes; and section 2 describes and reports results of an ACR workgroup–led process to develop specific criteria for ACR approval of quality measures.
Part One 1. Our Present Picture of the Universe 2. Clues from the History of Art 3. The Existence of an 'I' 4. The Ten Thousand Beings 5. The Practical Matter of Forging a Living Center Mid-Book Appendix: Recapitulation of the Argument Part Two 6. The Blazing One 7. Color and Inner Light 8. The Goal of Tears 9. Making Wholeness Heals the Maker 10. Pleasing Yourself 11. The Face of God
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