Kaili Shen

Zunyi Medical University

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Fushan Tang

Zunyi Medical University

Yingxu Chen

Dalian Ocean University

Chaofeng Shen

Zhejiang University

Xin Ma

Kunming Medical University

Fahai Cao

East China University of Science and Technology

Chengchen Yin

Shanghai Traditional Chinese Medicine Hospital

Haipeng Liu

Shanghai Pulmonary Hospital

Yongyong Luo

Zunyi Medical University

Qi Lin

Zhejiang University

Congkai Zhang

Yangtze University

Cooperative Institutions

East China University of Science and Technology

Zhejiang University

Chinese Academy of Sciences

State Key Laboratory of Chemical Engineering

Zunyi Medical University

Xiamen University

Ministry of Education of the People's Republic of China

Shandong University

University of Chinese Academy of Sciences

Shanghai Jiao Tong University

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Phanerochaete Chrysosporium Involvement In Medium pH Alteration And Speciation Of Cu At Goethite Surface

Environmental science : an Indian journal (2007)

Qi Lin Hongmei Zhao Kaili Shen Yingxu Chen

Batch experiments in the aerobic nutrient medium indicated that P.chrysosporium was involved in medium pH alteration and speciation of Cu at goethite surface. It was observed that pH alteration induced by P.chrysosporium was mineral dependant. The interaction between P.chrysosporium and goethite might shift the equilibrium to releasing more metal into the aqueous phase due to the decrease of pH in medium, sequestration of Cu by mycelium and formation of soluble organic Cu complex. The conversion of weakly bound Cu to aqueous Cu at the first 96 h of incubation was observed while strongly bound Cu remained nearly constant during the whole experimental period. The re-immobilization of Cu at 192 h was occurred in the presence of P.chrysosporium, which could be explained as being the result of both Cu precipitation with the increased pH and complexing of Cu by carboxyl, phenolic and carbonyl groups of the organic phase. In conclusion, P.chrysosporium-mineral interaction can play a key role in the cycling of trace elements in natural systems. A better understanding of fungal-mineral interactions is an urgent need to bioremediate the contaminated soil with fungi.

Phanerochaete

Chrysosporium

Genetic algorithm

Aqueous two-phase system

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Investigating influencing factors of medication adherence to inhalers in COPD patients: A study based on the Anderson model

Research Square (Research Square) (2024)

Chengchen Yin Yongyong Luo Kaili Shen Guangxin Mao Fushan Tang

Abstract Background Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality globally, imposing significant economic burden due to treatment costs. Non-adherence to inhaler therapy is common among COPD patients, contributing to increased hospitalization risk, disease progression, mortality rates, and reduced quality of life. Objective To investigate the factors influencing inhaler adherence in COPD patients and provide insights, for improving adherence. Methods A questionnaire based on Anderson model was administered to, COPD patients discharged from three tertiary hospitals in Zunyi City and those prescribed inhalers in respiratory departments. Results Only 30.90% of patients demonstrated good adherence to inhalers. Key influencing factors identified included contextual characteristics (e.g., management of chronic illness cards), and individual characteristics (e.g., family history, medication beliefs). Conclusion COPD patients exhibit suboptimal inhaler adherence. Pharmacists, in collaboration with healthcare professionals, communities, and patient families, should implement targeted interventions to address adherence-related factors and enhance patient quality of life.

Medication Adherence

10.21203/rs.3.rs-5302708/v1

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Study on influencing factors of medication adherence to inhalers in patients with COPD and asthma based on Anderson Model

Research Square (Research Square) (2024)

Chengchen Yin Yongyong Luo Kaili Shen Guangxin Mao Fushan Tang

Abstract Purpose To investigate the influencing factors of adherence to inhalers in patients with COPD and asthma, providing reference for improving the adherence to inhalers of patients with asthma and COPD. Methods A questionnaire was designed based on Anderson's model, and used to investigate the influencing factors of adherence to inhalers in COPD or asthma patients who were discharged inpatients or outpatients and had previously been prescribed inhalers in the respiratory departments of three tertiary hospitals in Zunyi City. Results Only 25.90% of patients demonstrate good adherence to inhalers. When combined with the Anderson model, the influencing factors of inhaler adherence in COPD and asthma patients can be summarized as follows: contextual characteristics (residential status, management of chronic illness cards), individual characteristics (disease condition, family history, medication beliefs) and outcomes (health status). Conclusion The medication adherence to inhalers in patients with COPD and asthma falls far short of being satisfactory. Pharmacists should collaborate with physician, nurses, communities, and patients' families, to proactively implement interventions targeting influencing factors of medication adherence to inhalers in patients with COPD and asthma. This will help improve patients' adherence to inhalers and, subsequently, enhance their quality of life.

Medication Adherence

Asthma medication

Dry-powder inhaler

10.21203/rs.3.rs-4878193/v1

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Synergistic electrocatalysis of polysulfides by a nanostructured VS₄-carbon nanofiber functional separator for high-performance lithium–sulfur batteries

Journal of Materials Chemistry A (2019)

Yongzheng Zhang Guixin Xu Qi Kang Liang Zhan Weiqiang Tang

Nanostructured VS₄ was in situ grown on defect-rich carbon nanofibers as a functional separator coating, which exerts the efficient entrapment and electrocatalysis of LiPS conversion.

Separator (oil production)

10.1039/c9ta03516h

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Citations (115)

Study on adverse impact of e-waste disassembly on surface sediment in East China by chemical analysis and bioassays

Journal of Soils and Sediments (2010)

Lei Chen Chunna Yu Chaofeng Shen Congkai Zhang Lei Liu

Luminescent bacteria

Electronic waste

Metalloid

10.1007/s11368-009-0176-8

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Citations (55)

PCB congeners induced mitochondrial dysfunction in Vero cells

Journal of Hazardous Materials (2010)

Kaili Shen Chaofeng Shen Jie Yu Chunna Yu Lei Chen

Congener

Vero cell

Viability assay

10.1016/j.jhazmat.2010.08.061

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Citations (26)

Hormesis response of marine and freshwater luminescent bacteria to metal exposure

Biological Research (2009)

Kaili Shen Chaofeng Shen Lu Yuan Xianjin Tang Congkai Zhang

The stimulatory effect of low concentrations of toxic chemicals on organismal metabolism, referred to as hormesis, has been found to be common in the widely used luminescence bioassay.This paper aims to study the hormesis phenomenon in both marine and freshwater luminescent bacteria, named Photobacterium phosphorem and Vibrio qinghaiensis.The effects of Cu (II), Zn (II), Cd (II) and Cr (VI) on luminescence of these two bacteria were studied for 0 to 75 minutes exposure by establishing dose-and time-response curves.A clear hormesis phenomenon was observed in all four testing metals at low concentrations under the condition of luminescence assays.

Hormesis

Luminescent bacteria

Photobacterium

Photobacterium phosphoreum

10.4067/s0716-97602009000200006

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Citations (44)

Comparison of structure-dependent hormetic cytotoxicity induced by coplanar and non-coplanar PCB congeners

Journal of Hazardous Materials (2010)

Yingxu Chen Kaili Shen Chaofeng Shen Lei Chen Xin Ma

Congener

Hormesis

10.1016/j.jhazmat.2010.04.041

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Citations (34)

Avoiding misdiagnosis of multilocular thymic cysts as malignant tumors on computer tomography

World Journal of Clinical Cases (2024)

Yuhong Zhang Yan-Miao Liu Kaili Shen Jingjing Wu Fushan Tang

This editorial provides insights from a case report by Sun

10.12998/wjcc.v12.i19.3671

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Citations (1)

Knowledge and Behavior in Rational Drug Use Among College Students in Zunyi City

Risk Management and Healthcare Policy (2022)

Chengchen Yin Xingkang He Kaili Shen Xingrui Mu Fushan Tang

To investigate the current status of knowledge and behavior about rational drug use in college students in different colleges and universities in a city in southwest China, providing reference for students' education of rational drug use in colleges and universities.A questionnaire survey on knowledge and behavior in rational drug use was carried out on the students recruited by occasional sampling method in 6 colleges and universities in Zunyi, China. Statistical analyses on demographic information and answers to questionnaire questions were carried out with SPSS 18.0.A total of 865 valid questionnaires were recovered from 923 questionnaires sent out. Some knowledge and behaviors of the students on drug use were irrational. There was statistically significant difference in some specific questions of the knowledge in rational drug use between medical and non-medical students (P<0.05); the average score of rational drug use behavior of medical students was lower than that of non-medical students (P<0.05); the average score of the rational drug use behavior of female students was lower than that of male (P<0.05); the students' major types had significantly different influence on their behavior in rational drug use (P<0.05). The school-carried pharmacy education can effectively improve students' rational medication; the majority of college students believed that it is necessary to popularize the knowledge of rational drug use on campus; and students' favorite way to acquire knowledge about rational drug use was to attend related lectures or elective courses.The knowledge and behavior of rational drug use among college students need to be improved. Professional medical education may exert a positive impact on rational drug use among college students. Thus, it is necessary to popularize the knowledge of rational drug use among college students, especially in non-medical colleges and universities.

Drug education

Irrational number

10.2147/rmhp.s347822

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Citations (11)