Xiaoxiao Hao

First Affiliated Hospital of Henan University

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R Zhang

Air Force Medical University

Rui Han

First Hospital of Jilin University

Zheng Chang

China Agricultural University

Longfei Yang

Nantong University

Ruihang Zhang

Northwest A&F University

Y.Y. Ma

Xijing Hospital

Meng-Yi Su

Xijing Hospital

Mengxiang Li

Shanghai Polytechnic University

Jian Wen

West China Hospital of Sichuan University

Yijuan Xin

Xijing Hospital

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Xijing Hospital

First Affiliated Hospital of Henan University

Air Force Medical University

Wenzhou Medical University

First Hospital of Jilin University

Jilin University

Kunming Medical University

First Affiliated Hospital of Kunming Medical University

Yan'an Hospital Affiliated To Kunming Medical University

Hebei Medical University

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Epidemiology, species distribution, antifungal susceptibility, and ERG11 mutations of Candida species isolated from pregnant Chinese Han women

Genetics and Molecular Research (2016)

Longfei Yang Meng-Yi Su Y.Y. Ma Yijuan Xin Rui Han

The widespread use of antifungal agents has led to increasing azole resistance in Candida species.A major azole-resistance mechanism involves point mutations in the ERG11 gene, which encodes cytochrome P450 lanosterol 14a-demethylase.In this study, vaginal swabs were obtained from 657 pregnant Chinese Han women and cultured appropriately.The open reading frame of the obtained fungal species were amplified by PCR and sequenced; additionally, the ERG11 gene of the isolated Candida species was amplified and sequenced, and the antifungal susceptibility of the isolated species was determined.The vaginal swabs of 124 women produced fungal cultures; five species of Candida were isolated from the patients, among which Candida albicans was predominant.Twelve C. albicans isolates (13.8%) were resistant to fluconazole and 2 (2.2%) were resistant to itraconazole.Seventeen mutations, including 9 silent and 8 missense mutations, were identified in the ERG11 gene of 31 C. albicans isolates.Our findings ©FUNPEC-RP www.funpecrp.com.brGenetics and Molecular Research 15 (2): gmr.15027168 suggest that infection caused by C. albicans and non-C.albicansis common in Chinese Han women of reproductive age.Moreover, the relationship between Candida infection and certain epidemiological factors emphasizes the need to educate women about the precise diagnosis and punctual treatment of vaginitis.

10.4238/gmr.15027168

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A Study of Peer Academic Support Mechanism Based on the Context of Dual-Line Integrated Teaching

Journal of Education Humanities and Social Sciences (2023)

Mengxiang Li Xiaoxiao Hao Yingmeng Ma Ruihang Zhang Zheng Chang

In recent years, students' academic pressure has grown exponentially due to various factors, including epidemics. This paper takes the Henan University of Chinese Medicine as an example and the educational requirements in implementing "the 14th Five-Year Plan for the Development of the Digital Economy" in higher Chinese medicine colleges and universities as the defined goal. The peer mutual aid mechanism is used as the main core, systematically elaborating the construction of the academic support mode of Chinese medicine colleges and universities under the academic background of dual-line fusion teaching. It is aimed to explore a method of academic support suitable for the current situation and help students get rid of academic pressure, which can contribute more to our society. It is argued that secondary colleges need to change the conventional idea of academic support. In the context of the rapid development of the Internet, we should take full advantage of the Internet development and combine it with the current education mode and student characteristics. As a result, we have proposed the "Two-multiple, One-precise, Both-balanced" concept of academic support. It provides a new way of understanding the academic support of Chinese medicine colleges under the background of dual-line fusion teaching.

Dual mode

Peer pressure

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Peer Instruction

10.54097/ehss.v23i.13932

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