C Schutte

Radboud University Nijmegen

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Reid Laughlin Skeel

Central Michigan University

Achuth Rao

RELX Group (Netherlands)

Kumar Ghosh

RELX Group (Netherlands)

Harm Svec

RELX Group (Netherlands)

N. Shivashankar

Impact Technology Development (United States)

E Dajer

RELX Group (Netherlands)

J. Ketan

PES University

Abigail Cox

Purdue University West Lafayette

Karin Roelofs

Radboud University Nijmegen

Johan Sundberg

KTH Royal Institute of Technology

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RELX Group (Netherlands)

Purdue University West Lafayette

Radboud University Nijmegen

Radboud University Medical Center

Google (United States)

National Institute of Mental Health and Neurosciences

Universidade Católica Portuguesa

University of Freiburg

University Medical Center Freiburg

Hochschule für Musik Freiburg

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Studying additive effects of combining rTMS with cognitive control training: a pilot investigation

Frontiers in Human Neuroscience (2023)

Iris Dalhuisen C Schutte Bob Bramson Karin Roelofs Philip van Eijndhoven

Repetitive transcranial magnetic stimulation (rTMS) on the dorsolateral prefrontal cortex (DLPFC) is an effective treatment for depression that has been proposed to work via the enhancement of cognitive control. Cognitive control training (CCT) can also alleviate depression by relying on DLPFC activation. As the additive effects of rTMS and CCT are unclear, we set out to conduct a within-subject pilot study in healthy controls.Seventeen participants received two sessions of individualized resting-state connectivity-guided high-frequency rTMS, while randomly performing CCT or a control task. After each session, a negative mood was induced.We found effects on mood and cognitive control after rTMS + CCT as well as rTMS + control, which were indiscriminative between conditions. Based on the statistical evidence for the absence of an additive effect of CCT, we did not perform a full study.Our results demonstrate no differential effects of single sessions combining rTMS and CCT in a healthy population, even with the methodological improvement of individualized neuronavigation. The improvement in cognitive control seen in both conditions could indicate that a simple cognitive task is sufficient when studying additive rTMS effects. Future studies should focus on augmenting the effects of various cognitive tasks and compare the present interventions with rTMS or cognitive tasks alone.

Cognitive Training

Dorsolateral prefrontal cortex

10.3389/fnhum.2023.1201344

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Journal of Voice (2023)

Jan Miller Harm Svec C Schutte I.-Min A. Chen Achuth Rao

10.1016/s0892-1997(23)00113-3

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Neuropsychological and Sensory Characteristics of Residents in a Continuing Care Retirement Community