Abstract BACKGROUND Due to the establishment of screening mammography for breast cancer detection, the number of non-palpable lesions has increased. Thus, an optimal localization system is mandatory for the excision of non-palpable breast tumors. OBJECTIVE the aim of the study is to report the feasibility Surgical Marker Navigation (SMN) system Sirius Pintuition® for the excision of non-palpable breast tumors and non-palpable axillary lymph nodes. METHODS A retrospective observational study of patients undergoing breast-conserving surgery and lymph node excision guided by SMN between December 2022 and May 2023 was performed. RESULTS A total of 84 patients underwent excision of non-palpable breast tumors (77; 91,7%) or non-palpable axillary lymph-nodes (7; 8,3%) using SMN. In total, 94 markers were placed, in 74 patients (88.1%) only one marker was placed, whereas in 10 patients (11.9%) two markers were placed to correctly localize the lesion in the operating room. Most markers were placed using ultrasonographic guidance (69; 82.1%). Seventy-seven patients underwent breast-conserving surgery (91.7%) and 7 (8.3%) lymph node excision. In 10 cases (11.9%), the marker was accidentally displaced during surgery due to the use of magnetized instruments, although the specimen could be removed. In sum, all the markers were removed from the patients, although the marker retrieval rate, as we defined it (percentage of patients in whom the initial excised specimen contained the marker divided by the total number of patients), was 88,1%. CONCLUSION The use of Sirius Pintuition® SMN for non-palpable breast tumors and non-palpable lymph nodes is feasible, with an excellent retrieval rate.

Single Center

Breast-conserving surgery

Surgical excision

Center (category theory)

10.21203/rs.3.rs-3890889/v1

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Citations (0)

125I Radioactive Seed Localization vs. Conventional Surgery for the Treatment of Mesenchymal Tumours: A Propensity Score Matching Analysis

Langenbeck s Archives of Surgery (2023)

Alberto G. Barranquero Sara Corral Moreno Alberto Martínez Lorca Lourdes Hernández‐Cosido María Eugenia Martín

10.1007/s00423-023-02907-3

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Citations (1)

Breast metastases from non-primary breast malignancies: What should we know?

Breast Disease (2023)

Ángela Santana Valenciano Luz Divina Juez Belén Perez‐Mies Sara Corral Moreno Sonia Rivas Fidalgo

Metastases from extramammary malignant neoplasms are very rare, accounting for less than 2% of all breast malignancies.The aim of this study is to describe the clinicopathological features and prognosis of breast metastases from non-primary breast malignancies at our institution.We performed a retrospective observational study, obtaining data from electronic medical records and pathology databases between January 1985 and December 2020 for patients diagnosed with breast metastasis from non-primary breast malignancies. Only patients diagnosed by biopsy were included.Fifteen patients diagnosed with breast metastases from non-primary breast malignancies were included, 13 women (86,67%) and 2 men (13,33%). The median age at time of initial diagnosis was 56 years (IQR 21-68). The most frequent primary malignancy was melanoma (9/15; 60%). The median time to diagnosis of breast metastases was 65 months (IQR 13-106). The most common diagnostic modality was CT-scan (10/15; 66,67%). The median follow-up was 96 months (IQR 29-136). Eight patients underwent surgery (53,3%), being the most common surgical intervention breast-conserving surgery (5/8; 62,5%). Mortality at the end of follow-up was 53,3% (8/15). On the survival analysis, we found no differences between patients undergoing surgery and those only receiving systemic treatment [41,5 months (IQR 17,5-57,5) versus 14 months (IQR 2-24), respectively; p = 0,161].Breast metastases from non-primary breast malignancies are extremely rare and represent a diagnostic and therapeutic challenge, due to the poor prognosis of these patients. Thus, arriving at the correct diagnosis is crucial to avoid unnecessary treatment in this population.

Medical record

Breast-conserving surgery

Primary tumor

10.3233/bd-220056

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Citations (2)

Surgical considerations about amyloid goiter

Endocrinología y Nutrición (English Edition) (2013)

Augusto Villanueva María Jesús García Villanueva Mercedes García Villanueva Roberto Rojo Blanco María Vicenta Collado Guirao

Amyloid (mycology)

10.1016/j.endoen.2013.06.001

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Citations (3)