Felipe Gabriel

Universidade de Brasília

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Victoria Guiral

Hospital Clínico Universitario de Valencia

Manuel Labiós

Hospital Clínico Universitario de Valencia

João Pedro dos Santos Ferreira

Giulia Lordello

Eduarda Vitória

Karla Motta

Instituto Federal do Rio Grande do Norte

Jorge Hernandez Montes

María de la Luz Casas Martínez

Universidad Autónoma de Santo Domingo

Manuel Monréal

Universidad Católica San Antonio de Murcia

Ester Macedo

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262

Universidade de Brasília

261

King's College London

University of Nottingham

University of Leicester

Universidade de São Paulo

National Institute for Health Research

Hospital Universitari i Politècnic La Fe

Nottingham University Hospitals NHS Trust

Nottingham Biomedical Research Centre

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Effects of eprosartan on mitochondrial membrane potential and H2O2 levels in leucocytes in hypertension

Journal of Human Hypertension (2008)

Manuel Labiós María de la Luz Casas Martínez Felipe Gabriel Victoria Guiral Sandra Ruiz-Aja

Pathogenesis

Dichlorofluorescein

Olmesartan

10.1038/jhh.2008.19

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Citations (17)

ASGBI Abstracts 2009: Oral Presentations

British journal of surgery (2009)

Ashar Wadoodi Prakash Saha Catherine Evans Shivani Patel Matthew Waltham

Abstract The Annual Scientific Meeting of the Association of Surgeons of Great Britain and Ireland takes place this year at the Scottish Exhibition and Conference Centre, Glasgow, UK (13th–15th May 2009), under the presidency of Professor Michael Horrocks.

Presidency

10.1002/bjs.6640

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Idiopathic versus secondary venous thromboembolism. Findings of the RIETE registry

Revista Clínica Española (English Edition) (2014)

José María Pedrajas C. Garmendia Jorge López‐Portillo Felipe Gabriel C. Mainez

10.1016/j.rceng.2014.05.002

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Citations (4)

Edição nº4 - Jornal do 3D Colégios

Zenodo (CERN European Organization for Nuclear Research) (2022)

Denise Moraes do Nascimento Vieira João Pedro dos Santos Ferreira Ronnie Henrique de Oliveira Martins Curty Carlos Henrique Freitas da Cunha Leonam Douglas

10.5281/zenodo.7422733

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Un cas de larva migrans cutanée acquise à Bordeaux : impact du réchauffement climatique ?

Annales de Dermatologie et de Vénéréologie (2015)

Anne Goiset S. Etesse-Pichon Éric Caumes Thierry Pistone Felipe Gabriel

10.1016/j.annder.2015.10.392

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Clinical outcomes in cancer patients with concurrent venous thromboembolism: findings from the RIETE registry

Hematology Meeting Reports (formerly Haematologica Reports) (2009)

Manuel Monréal C. Falgá Blanca Vilaseca C. Suárez Felipe Gabriel

n cancer patients who develop venous thromboembolism (VTE) the risk of death is more than threefold higher than in patients without cancer who have VTE1-3 and in those with cancer but no VTE.4 The high mortality rate in cancer patients with VTE is probably due to both the VTE and the fact that malignancies associated with VTE appear to follow a more aggressive course. Identifying clinical characteristics that put cancer patients with VTE at increased risk of death, either due to PE or bleeding complications, is important if their outcomes are to be improved.

Major bleeding

10.4081/hmr.v1i9.334

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Citations (3)

Effect of eprosartan on cytoplasmic free calcium mobilization, platelet activation, and microparticle formation in hypertension

American Journal of Hypertension (2004)

Manuel Labiós María Teresa Martínez Felipe Gabriel Victoria Guiral A MUNOZ

Hypertensive patients show greater platelet activation than do normotensive individuals. Platelet activation is characterized by increased phosphatidylserine (PS) exposure in the external hemilayer of the membrane, a larger number of platelet microparticles (PMP), and changes in intraplatelet-free calcium kinetics. This study evaluated whether eprosartan can protect against undesirable platelet activation.A total of 30 hypertensive patients (systolic blood pressure [SBP] 140 to 189 mm Hg; diastolic blood pressure [DBP] 90 to 109 mm Hg) without renal, liver, or cardiac organic lesions and with a mean age of 47.6 +/- 9.4 years and mean body mass index (BMI) of 27.9 +/- 3.9 kg/m2 received eprosartan (600 mg/day). They were compared with 31 normotensive individuals with a mean age of 43.3 +/- 6.7 years and a mean BMI of 26.8 +/- 3.9 kg/m2. Blood pressure measurements and platelet function changes were assessed at baseline (control and hypertensive patients) and after 1 and 2 months of eprosartan monotherapy (hypertensive patients only).Significant baseline to endpoint (month 2) changes in SBP and DBP were noted in the eprosartan group (SBP: baseline 152.2 +/- 16.8 mm Hg, endpoint 142.2 +/- 16.9 mm Hg, P <.01; DBP: baseline 93.5 +/- 9.9 mm Hg, endpoint 85.8 +/- 11.9 mm Hg, P <.001). Native circulating activated platelets increased in both groups after shear stress or Ca2+ ionophore activation, and were reduced by eprosartan (after shear exposure from 104% at month 1 to 76% after 2 months of therapy). Eprosartan therapy normalized the number of microparticles after blood shear exposure (P <.01) and after exposure to Ca2+ ionophore activation (P <.05) and significantly reduced the trend for platelets to be more readily activated in hypertensive compared with normotensive subjects (baseline to endpoint change P <.001; increase/shear versus baseline P <.001). Eprosartan partially normalizes cytoplasmic-free calcium mobilization in platelets.Eprosartan significantly reduces blood pressure and normalizes undesirable changes in platelet function.

10.1016/j.amjhyper.2004.05.010

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Citations (42)

The effect of long-term treatment with hypotensive drugs on blood viscosity and erythrocyte deformability in patients with essential arterial hypertension.

PubMed (1997)

M.U. Martínez Martínez Amparo Vayá Manuel Labiós Felipe Gabriel Victoria Guiral

This study examined ninety-six patients with essential arterial hypertension (WHO grade I-II) who had been under treatment for a period of at least one year before participating in the study. When the study began the patients received no drug treatment for one month. At the end of this washout period their basal situation was evaluated and drug treatment was begun (26 patients on calcium antagonists, 39 on beta-blockers and 31 on angiotensin converting enzyme inhibitors). The patients were evaluated again after one and two years of uninterrupted treatment with the chosen medication. The results obtained indicate that in a basal situation hypertensive patients have higher blood viscosity and erythrocyte rigidity values than the control group. Regardless of the drug treatment used, the patients experienced during the study a progressive deterioration of their hemorheological situation consisting of an increase in red blood cell rigidity and increased blood viscosity. These results indicate the importance of evaluating the hemorheological parameters of hypertensive patients and suggest that it may be advisable to include in their treatment some kind of medication that prevents progressive rheological deterioration.

Basal (medicine)

Erythrocyte deformability

Erythrocyte aggregation

Washout

Drug treatment

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Citations (14)

EFFECT OF EPROSARTAN ON PLATELET ACTIVATION AND MICROPARTICLES FORMATION IN HYPERTENSION. STUDY BY WHOLE BLOOD FLOW CYTOMETRY

Journal of Hypertension (2004)

Manuel Labiós María de la Luz Casas Martínez Felipe Gabriel Victoria Guiral Sarai Palanca

: Monday, June 14, 2004: ORAL SESSIONS: Poster Session 18: Therapeutics and Clinical Pharmacology

10.1097/00004872-200406002-00412

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Alquimias do movimento: XI Mexido

R.C. Silva Soraia Maria Néliton Rreira Martins Alves Samuel Filho

Esse livro Alquimias do Movimento: XI Mexido, contém artigos que reverberam as pesquisas apresentadas no evento homônimo e é resultado de reflexões teórico/práticas realizadas durante a disciplina Movimento e Linguagem 2 ofertada para a graduação do Departamento de Artes Cênicas CEN/UnB e disciplina TEAC 01 - turma 6 autointitulada de Técnicas Experimentais Tecnológicas em Situação de Solidão no segundo semestre de 2020.

10.26512/9786588507032

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