Andre A. Eggen

Illumina (United States)

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Hélène Hayes

AgroParisTech

Didier Boichard

Génétique Animale et Biologie Intégrative

Hubert H. Levéziel

Université de Limoges

Mathieu Gautier

Centre de Biologie et de Gestion des Populations

Sébastien Fritz

Génétique Animale et Biologie Intégrative

Cécile Grohs

Génétique Animale et Biologie Intégrative

Pascal Laurent

Université Libre de Bruxelles

Sandrine Floriot

Génétique Animale et Biologie Intégrative

Alain Ducos

École Nationale Vétérinaire de Toulouse

Philippe Bessières

Mathématiques et Informatique Appliquées du Génome à l'Environnement

Cooperative Institutions

Institut National de la Recherche Agronomique

104

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

103

Université Paris-Saclay

Département Génétique Animale

Centre National de la Recherche Scientifique

Baylor College of Medicine

Génétique Animale et Biologie Intégrative

Agricultural Research Service

National Institutes of Health

Inserm

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Chromosomal homology between the human and the bovine DMRT1 genes.

Folia Biologica (2009)

Anna Bratus-Neuenschwander M. Bugno Jolanta Klukowska‐Rötzler Małgorzata Sawińska Andre A. Eggen

Doublesex and mab-3 related transcription factor 1 (DMRT1) is considered to be the most conserved gene among loci involved in the molecular pathways of animal sexual development. In the majority of the extensively examined vertebrates, its function is limited to the upstream or downstream testis regulators acting during embryogenesis. Our present study demonstrated the structural homology between DMRT1 orthologos in human and cattle. A BAC clone with a specific bovine sequence of the gene was used in the FISH mapping experiments. The physical localization of DMRT1 in cattle (BTA 8q17) was determined and its homology to the human locus was shown (HSA 9p24.3). Furthermore, another BAC probe, containing the sequence of the human homologue (pBACe3.6), generated hybridisation signals on bovine metaphase chromosomes and indicated the physical location of the autosomal bovine DMRT1 locus. Further investigations of the gene in domestic animals might provide more support for its conservative status and may help in understanding the molecular mechanisms involved in the occurrence of sexual abnormalities often diagnosed in livestock.

Doublesex

Homology

Sexual Differentiation

Source

Cite

Citations (2)

Le gène "Bulldog" est localisé

HAL (Le Centre pour la Communication Scientifique Directe) (2000)

Andre A. Eggen

Source

Cite

Citations (0)

Genetic defects in cattle

HAL (Le Centre pour la Communication Scientifique Directe) (2002)

Alain Ducos Andre A. Eggen Roland Darré Didier Boichard

Source

Cite

Citations (0)

The BOVMAP database.

HAL (Le Centre pour la Communication Scientifique Directe) (1996)

S. Gas Andre A. Eggen Franck Samson C. Christophe C. Mungall

Source

Cite

Citations (0)

Les travaux de la recherche sur le gène "sans cornes"

HAL (Le Centre pour la Communication Scientifique Directe) (2000)

Andre A. Eggen François Ménissier

Source

Cite

Citations (0)

The BOVMAP database.

HAL (Le Centre pour la Communication Scientifique Directe) (1996)

S. Gas Andre A. Eggen Franck Samson C. Christophe C. Mungall

Source

Cite

Citations (0)

Un projet d'épidémiosurveillance pour les anomalies héréditaires bovines

HAL (Le Centre pour la Communication Scientifique Directe) (2003)

Alain Ducos Andre A. Eggen Roland Darré Didier Boichard

Source

Cite

Citations (0)

Genetic and Haplotypic Structure in 14 European and African Cattle Breeds

Genetics (2007)

Mathieu Gautier Thomas Faraut Katayoun Moazami‐Goudarzi Vincent Navratil Mario Foglio

To evaluate and compare the extent of LD in cattle, 1536 SNPs, mostly localized on BTA03, were detected in silico from available sequence data using two different methods and genotyped on samples from 14 distinct breeds originating from Europe and Africa. Only 696 SNPs could be validated, confirming the importance of trace-quality information for the in silico detection. Most of the validated SNPs were informative in several breeds and were used for a detailed description of their genetic structure and relationships. Results obtained were in agreement with previous studies performed on microsatellite markers and using larger samples. In addition, the majority of the validated SNPs could be mapped precisely, reaching an average density of one marker every 311 kb. This allowed us to analyze the extent of LD in the different breeds. Decrease of LD with physical distance across breeds revealed footprints of ancestral LD at short distances (<10 kb). As suggested by the haplotype block structure, these ancestral blocks are organized, within a breed, into larger blocks of a few hundred kilobases. In practice, such a structure similar to that already reported in dogs makes it possible to develop a chip of <300,000 SNPs, which should be efficient for mapping purposes in most cattle breeds.

10.1534/genetics.107.075804

Cite

Citations (150)

Assignment of eight additional genes from human chromosome 11 to bovine chromosomes 15 and 29: refinement of the comparative map.

HAL (Le Centre pour la Communication Scientifique Directe) (2001)

Mathieu Gautier Hélène Hayes Séad Taourit Pascal Laurent Andre A. Eggen

Source

Cite

Citations (0)

Bovine synteny group U7, previously assigned to G-banded chromosome 25 in the ISCNDA nomenclature, assigns to R-banded chromosome 29.

HAL (Le Centre pour la Communication Scientifique Directe) (1994)

Andre A. Eggen Anne Oustry Daniel Vaiman L. Ferretti R. Fries

Synteny

Source

Cite

Citations (0)