Abenavoli Carmelo

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Takeo Nomi

Institute Mutualiste Montsouris

J. Zemour

Peuplements végétaux et bioagresseurs en milieu tropical

ÉG

Édouard Girard

Université Grenoble Alpes

A. Mulliri

Université de Caen Normandie

Charles Vanbrugghe

Hôpital Européen

Olivier Turini

Institut Paoli-Calmettes

Emmanuel Boleslawski

Hôpital Claude Huriez

Fabrice Muscari

Centre Hospitalier Universitaire de Toulouse

H. Fagot

Peuplements végétaux et bioagresseurs en milieu tropical

Christophe Laurent

Hôpital Cardiologique du Haut-Lévêque

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Assistance Publique – Hôpitaux de Paris

Sorbonne Université

Inserm

Pitié-Salpêtrière Hospital

Hôpitaux Universitaires Henri-Mondor

Centre de Recherche Saint-Antoine

Université Paris Cité

Hôpital Paul-Brousse

Simplification des soins chez les patients complexes

Université Claude Bernard Lyon 1

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Impact of cirrhosis in patients undergoing laparoscopic liver resection in a nationwide multicentre survey

British journal of surgery (2020)

Christian Hobeika David Fuks François Cauchy Claire Goumard Olivier Soubrane

Abstract Background The aim was to analyse the impact of cirrhosis on short-term outcomes after laparoscopic liver resection (LLR) in a multicentre national cohort study. Methods This retrospective study included all patients undergoing LLR in 27 centres between 2000 and 2017. Cirrhosis was defined as F4 fibrosis on pathological examination. Short-term outcomes of patients with and without liver cirrhosis were compared after propensity score matching by centre volume, demographic and tumour characteristics, and extent of resection. Results Among 3150 patients included, LLR was performed in 774 patients with (24·6 per cent) and 2376 (75·4 per cent) without cirrhosis. Severe complication and mortality rates in patients with cirrhosis were 10·6 and 2·6 per cent respectively. Posthepatectomy liver failure (PHLF) developed in 3·6 per cent of patients with cirrhosis and was the major cause of death (11 of 20 patients). After matching, patients with cirrhosis tended to have higher rates of severe complications (odds ratio (OR) 1·74, 95 per cent c.i. 0·92 to 3·41; P = 0·096) and PHLF (OR 7·13, 0·91 to 323·10; P = 0·068) than those without cirrhosis. They also had a higher risk of death (OR 5·13, 1·08 to 48·61; P = 0·039). Rates of cardiorespiratory complications (P = 0·338), bile leakage (P = 0·286) and reoperation (P = 0·352) were similar in the two groups. Patients with cirrhosis had a longer hospital stay than those without (11 versus 8 days; P = 0·018). Centre expertise was an independent protective factor against PHLF in patients with cirrhosis (OR 0·33, 0·14 to 0·76; P = 0·010). Conclusion Underlying cirrhosis remains an independent risk factor for impaired outcomes in patients undergoing LLR, even in expert centres.

10.1002/bjs.11406

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Benchmark performance of laparoscopic left lateral sectionectomy and right hepatectomy in expert centers

Journal of Hepatology (2020)

Christian Hobeika David Fuks François Cauchy Claire Goumard Brice Gayet

Benchmarking

10.1016/j.jhep.2020.05.003

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Sex differences in alcohol use disorders the role of steroid hormones

General Internal Medicine and Clinical Innovations (2016)

Rosanna Mancinelli Carolina Ferranti Marco Famele Luca Palleschi Abenavoli Carmelo

Gonadal Steroid Hormones

Steroid use

Sex steroid

Sex hormone receptor

10.15761/gimci.1000130

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Laparoscopic versus open resection of intrahepatic cholangiocarcinoma: nationwide analysis

British journal of surgery (2021)

Christian Hobeika François Cauchy David Fuks Louise Barbier Jean‐Michel Fabre

The relevance of laparoscopic resection of intrahepatic cholangiocarcinoma (ICC) remains debated. The aim of this study was to compare laparoscopic (LLR) and open (OLR) liver resection for ICC, with specific focus on textbook outcome and lymph node dissection (LND).Patients undergoing LLR or OLR for ICC were included from two French, nationwide hepatopancreatobiliary surveys undertaken between 2000 and 2017. Patients with negative margins, and without transfusion, severe complications, prolonged hospital stay, readmission or death were considered to have a textbook outcome. Patients who achieved both a textbook outcome and LND were deemed to have an adjusted textbook outcome. OLR and LLR were compared after propensity score matching.In total, 548 patients with ICC (127 LLR, 421 OLR) were included. Textbook-outcome and LND completion rates were 22.1 and 48.2 per cent respectively. LLR was independently associated with a decreased rate of LND (odds ratio 0.37, 95 per cent c.i. 0.20 to 0.69). After matching, 109 patients remained in each group. LLR was associated with a decreased rate of transfusion (7.3 versus 21.1 per cent; P = 0.001) and shorter hospital stay (median 7 versus 14 days; P = 0.001), but lower rate of LND (33.9 versus 73.4 per cent; P = 0.001). Patients who underwent LLR had lower rate of adjusted TO completion than patients who had OLR (6.5 versus 17.4 per cent; P = 0.012).The laparoscopic approach did not substantially improve quality of care of patients with resectable ICC.

Intrahepatic Cholangiocarcinoma

10.1093/bjs/znaa110

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電子タバコ補充液体と中古生成したエーロゾル中のニコチンと小タバコアルカロイドの定量のためのタンデム質量分析法を用いた液体クロマトグラフィー【Powered by NICT】

Journal of Separation Science (2017)

Marco Famele Palmisani Jolanda Carolina Ferranti Abenavoli Carmelo Luca Palleschi

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HeartMate 3を用いた持続性左室補助装置置換術の早期転帰【JST・京大機械翻訳】

Journal of Thoracic and Cardiovascular Surgery (2020)

Dana Yaron M Wojnarski Charles Parichart Junpaparp K. Oliver Han Billard

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