Milica Mitrović

Univerzitetski Klinički Centar Srbije

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Boris Tadić

University of Belgrade

Jelena Djokić Kovač

University of Belgrade

Aleksandra Janković

University of Belgrade

Nikola Grubor

University of Belgrade

Petar Djurić

Kliničko Bolnički Centar Zvezdara

Vladimir Dugalić

University of Belgrade

Aleksandar Janković

Kliničko Bolnički Centar Zvezdara

Nada Dimković

University of Belgrade

Milan Pantelic

Henry Ford Health System

M Milanov

Kliničko Bolnički Centar Zvezdara

Cooperative Institutions

University of Belgrade

Univerzitetski Klinički Centar Srbije

Centar za Promociju Nauke

Center for Health, Exercise and Sport Sciences

University of Birmingham

Kliničko Bolnički Centar Zvezdara

University Medical Center

NIHR Birmingham Biomedical Research Centre

Yorkshire Cancer Research

Urology Foundation

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Pancreatic Hydatid Cyst Misdiagnosed as Mucinous Cystadenoma: CT and MRI Findings

Medicina (2020)

Milica Mitrović Boris Tadić Jelena Kovac Nikola Grubor Vladimir Milosavljević

Isolated hydatid cysts of the pancreas are rare lesions, even in endemic regions. In this report, we present the case of a 76-year-old patient who was admitted to our clinic with a diagnosis of a cystic lesion in the tail of the pancreas. On preoperative computed tomography (CT) and magnetic resonance (MR) examination, the cyst was characterized as a mucinous cystadenoma. A laparoscopic distal pancreatectomy followed. A histopathological examination revealed a large hydatid cyst in the tail of the pancreas.

Mucinous cystadenoma

Hydatid cyst

Cystadenoma

Histopathological examination

Distal pancreatectomy

10.3390/medicina56030124

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Citations (11)

MO023EFFECTS OF SODIUM THIOSULFATE ON VASCULAR CALCIFICATIONS IN HEMODIALYSIS PATIENTS: A INTERVENTIONAL DOUBLE BLINDED RANDOMISED PLACEBO CONTROLED STUDY

Nephrology Dialysis Transplantation (2017)

Petar Djurić Georg Schlieper Živka Djurić Milan Pantelic Milica Mitrović

Sodium thiosulfate

10.1093/ndt/gfx117.mo023

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Anatomical variations of posterior cerebral circulation: a comprehensive evaluation using MDCT angiography

Ana Stanković Jelena Kovac Tatjana Nikolić Milica Mitrović Goran Miličević

Poster: ECR 2013 / C-1321 / Anatomical variations of posterior cerebral circulation: a comprehensive evaluation using MDCT angiography by: A. Stankovic1, J. Kovac1, T. NIKOLIC1, M. Mitrovic1, G. Milicevic1, D. Stankovic1, D. Vasin1, T. Stosic-Opincal2; 1Belgrade/RS, 2Beograd/RS

Cerebral circulation

Circulation (fluid dynamics)

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The role of quantitative diffusion-weighted imaging in characterization of hypovascular liver lesions: A prospective comparison of intravoxel incoherent motion derived parameters and apparent diffusion coefficient

PLoS ONE (2021)

Jelena Djokić Kovač Marko Daković Aleksandra Janković Milica Mitrović Vladimir Dugalić

Background The utility of intravoxel incoherent motion (IVIM) related parameters in differentiation of hypovascular liver lesions is still unknown. Purpose The purpose of this study was to evaluate the value of IVIM related parameters in comparison to apparent diffusion coefficient (ADC) for differentiation among intrahepatic mass-forming cholangiocarcinoma (IMC), and hypovascular liver metastases (HLM). Methods Seventy-four prospectively enrolled patients (21 IMC, and 53 HLM) underwent 1.5T magnetic resonance examination with IVIM diffusion-weighted imaging using seven b values (0–800 s/mm 2 ). Two independent readers performed quantitative analysis of IVIM-related parameters and ADC. Interobserver reliability was tested using a intraclass correlation coefficient. ADC, true diffusion coefficient ( D ), perfusion-related diffusion coefficient ( D *), and perfusion fraction (ƒ) were compared among the lesions using Kruskal-Wallis H test. The diagnostic accuracy of each parameter was assessed by receiver operating characteristic (ROC) curve analysis. Results The interobserver agreement was good for ADC (0.802), and excellent for D , D *, and ƒ (0.911, 0.927, and 0.942, respectively). ADC, and D values were significantly different among IMC and HLM (both p < 0.05), while there was no significant difference among these lesions for ƒ and D * ( p = 0.101, and p = 0.612, respectively). ROC analysis showed higher diagnostic performance of D in comparison to ADC (AUC = 0.879 vs 0.821). Conclusion IVIM-derived parameters in particular D , in addition to ADC, could help in differentiation between most common hypovascular malignant liver lesions, intrahepatic mass—forming cholangiocarcinoma and hypovascular liver metastases.

Intravoxel incoherent motion

10.1371/journal.pone.0247301

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Citations (7)

IDENTIFYING WOMEN WITH PSYCHOLOGICAL PROBLEMS DURING THE IN VITRO FERTILIZATION PROCESS: THE PSYCHOLOGICAL EVALUATION TEST (PET)

Facta Universitatis Series Philosophy Sociology Psychology and History (2022)

Jelena Opsenica Kostić Milica Mitrović

Especially strong or inadequate emotional reactions during in vitro fertilization (IVF) treatment may affect both the success of the treatment and later mental health. This study tested the possibility of using Psychological Evaluation Test for Infertile Couples (PET) scores to identify women with psychological problems during the IVF process, so that they can be offered psychological counseling. The sample comprised 158 women, all of whom were undergoing the IVF treatment at the time of the study, and 128 women who had at least one child conceived without difficulties. All of the respondents filled in a questionnaire concerning their emotional status and coping competencies, while the PET was given only to the respondents undergoing IVF. Respondents with higher PET scores (> 30) have significantly higher Negative Affectivity and Shame in front of others, and lower Positive Affectivity and Coping competencies than the group with low PET scores (≤ 30) and women who conceived without difficulties. Respondents with lower PET scores do not significantly differ from women who conceived without difficulties. The results obtained suggest that the PET cut-off score > 30 may be considered a reliable measure to identify women with psychological problems i.e., reaching scores of > 30 can be taken as an indicator of the need for psychological support.

Psychological Well-Being

Shame

Psychological Testing

10.22190/fupsph2202087o

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Citations (2)

Isolated Splenic Metastasis of Primary Lung Cancer Presented as Metachronous Oligometastatic Disease—A Case Report

Diagnostics (2022)

Milorad Reljic Boris Tadić Katarina Stošić Milica Mitrović Nikola Grubor

Modern oncology practice and new antitumor drugs prolonged disease-free intervals in patients with lung cancer. Patients with distant metastatic disease are treated only with palliative intent. The International Association for the Study of Lung Cancer, in the 8th edition of the TNM classification, for the first time includes oligometastatic disease as a clinical state that describes the patients with distant metastasis, limited in number and organ sites, who may have more indolent biology. In this paper, we present a case of a 56-year-old man who was admitted to our clinic regarding a radiologically diagnosed splenic lesion of uncertain nature, and who underwent a left upper lobectomy for primary lung cancer 12 years before. After a detailed radiological diagnosis, it was concluded that it is highly suspected metastatic lesion of the spleen and the patient underwent a splenectomy. While no definitive protocols exist on the management of isolated splenic metastasis from lung cancer, splenectomy, in suitable patients, with reasonable survival expectations, improves patient disease-free survival and can prevent potentially life-threatening complications, such as splenic rupture. 18F-FDG PET has very high sensitivity and specificity for differentiating benign and malignant splenic lesions especially in patients who are in the follow up protocol due to primary malignancy.

Primary tumor

10.3390/diagnostics12010209

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Citations (5)

Sodium thiosulphate and progression of vascular calcification in end-stage renal disease patients: a double-blind, randomized, placebo-controlled study

Nephrology Dialysis Transplantation (2019)

Petar Djurić Nada Dimković Georg Schlieper Živka Djurić Milan Pantelic

Abstract Background Sodium thiosulphate (NaTS) is mostly used in haemodialysis (HD) patients with calcific uraemic arteriolopathy. This double-blind, randomized, placebo-controlled study assessed the effect of NaTS on progression of cardiovascular calcifications in HD patients. Methods From 65 screened patients, we recruited 60 patients with an abdominal aorta Agatston calcification score ≥100. Thirty patients were randomized to receive NaTS 25 g/1.73 m2 and 30 patients to receive 100 mL of 0.9% sodium chloride intravenously during the last 15 min of HD over a period of 6 months. The primary endpoint was the absolute change of the abdominal aortic calcification score. Results The abdominal aortic calcification score and calcification volume of the abdominal aorta increased similarly in both treatment groups during the trial. As compared with the saline group, patients receiving NaTS exhibited a reduction of their iliac artery calcification score (−137 ± 641 versus 245 ± 755; P = 0.049), reduced pulse wave velocity (9.6 ± 2.7 versus 11.4 ± 3.6; P = 0.000) and a lower carotid intima-media thickness (0.77 ± 0.1 versus 0.83 ± 00.17; P = 0.033) and had better preservation of echocardiographic parameters of left ventricular hypertrophy. No patient of the NaTS group developed new cardiac valve calcifications during the trial as compared with 8 of 29 patients in the saline group. By univariate analysis, NaTS therapy was the only predictor of not developing new valvular calcifications. No adverse events possibly related to NaTS infusion were noted. Conclusions While NaTS failed to retard abdominal aortic calcification progress, it positively affected calcification progress in iliac arteries and heart valves as well as several other cardiovascular functional parameters.

Abdominal aorta

10.1093/ndt/gfz204

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Citations (37)

Encapsulated Omental Necrosis as an Unexpected Postoperative Finding: A Case Report

Medicina (2021)

Milica Mitrović Dejan Veličković Marjan Micev Vladimir Šljukić Petar Djurić

Postsurgical fat necrosis is a frequent finding in abdominal cross-sectional imaging. Epiploic appendagitis and omental infarction are a result of torsion or vascular occlusion. Surgery or pancreatitis are conditions that can have a traumatic and ischemic effect on fatty tissue. The imaging appearances may raise concerns for recurrent malignancy, but percutaneous biopsy and diagnostic follow-up assist in the accurate diagnosis of omental infarction. Herein we describe a case of encapsulated omental necrosis temporally related to gastric surgery. Preoperative CT and MRI findings showed the characteristics of encapsulated, postcontrast nonviable tumefaction in the epigastrium without clear imaging features of malignancy. Due to the size of the lesion and the patient’s primary disease, tumor recurrence could not be completely ruled out, and the patient underwent surgery. Histopathological analysis confirmed the diagnosis of steatonecrosis of the omentum.

10.3390/medicina57090865

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Citations (3)

Emergency abdominal ultrasound as sufficient diagnostic modality in the diagnosis of biliary ileus

SANAMED (2020)

Milica Mitrović Nevena Stanišić Zlatko Perišić Ivana Lešević Dragan Vasin

Introduction: Biliary ileus is a rare emergency condition that mainly affects the elderly population, with a predominance of females and a mortality rate of 12-27%. It is a mechanical intestinal obstruction caused by the impaction of the biliary calculus within the gastrointestinal tract. It occurs due to the formation of bilio-enteric fistula, as a rare complication of cholelithiasis. Case report: A 73-year-old male patient with epigastric pain, nausea and vomiting was referred for ultrasound exam. The analysis of the clinical-biochemical status of the patient as well as the ultrasound examination of the abdomen itself raised the suspicion of small intestine obstruction, due to the enclaved biliary calculus. After an urgent exploratory laparotomy, the diagnosis was confirmed, and enterotomy was successfully performed with calculus extraction. Cholecysto-duodenal fistula has been confirmed as a major cause of biliary ileus. The post-operative course was uneventful. Conclusion: This case report highlights the enormous importance of ultrasound diagnostics in diagnosing biliary ileus using the criteria of The Rigler Triad, which includes pneumobilia, intestinal obstruction and ectopic calculus. Initially unrecognised cause of obstruction and a late diagnosis correlated with bad prognosis. Ultrasonographic examination of these patients can be a sufficient diagnostic modality in making an accurate diagnosis and further surgical treatment of these patients

Gallstone Ileus

Ileus

Exploratory laparotomy

Enterotomy

10.24125/sanamed.v15i3.476

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Citations (1)

FP631EFFECTS OF SODIUM THIOSULFATE ON CALCIFICATION OF ILIAC ARTERIES IN HEMODIALYSIS PATIENTS- A INTERVENTIONAL DOUBLE BLIND RANDOMIZED PLACEBO CONTROLLED STUDY

Nephrology Dialysis Transplantation (2019)

Petar Djurić Georg Schlieper Živka Djurić Milan Pantelic Aleksandar Janković

Sodium thiosulfate

10.1093/ndt/gfz106.fp631

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Citations (0)