Sven Mueller

University of Tübingen

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Andreas Kirschniak

Kliniken Maria Hilf

Manuel Braun

University of Stuttgart

Claudius Falch

University Children's Hospital Tübingen

Alfred Koenigsrainer

University of Tübingen

Bernhard Klumpp

University of Tübingen

FÖ

Frank Örner -Rock

Science and Technology on Surface Physics and Chemistry Laboratory

Martin E. Maier

University of Tübingen

Peter Overath

University of Tübingen

Udo Weimar

University of Tübingen

Cihan Gani

University Children's Hospital Tübingen

Cooperative Institutions

University of Tübingen

University Children's Hospital Tübingen

Universitätsklinikum Tübingen

Heidelberg University

German Cancer Research Center

Institute for Bioengineering of Catalonia

Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine

University of Freiburg

Deutschen Konsortium für Translationale Krebsforschung

Bernstein Center for Computational Neuroscience Tübingen

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Anorectal malignant melanoma: curative abdominoperineal resection: patient selection with 18F-FDG-PET/CT

World Journal of Surgical Oncology (2016)

Claudius Falch Sven Mueller Andreas Kirschniak Manuel Braun Alfred Koenigsrainer

Anorectal malignant melanomas (ARMM) are rare tumors, characterized by an early lymphatic spread and distant metastasis, resulting in an extremely poor overall survival. The objective of this study was to determine the pattern of regional lymph node metastasis (LNM) by computed tomography (CT) and 18F-FDG-PET/CT in patients undergoing abdominoperineal resection (APR) and its impact on oncologic outcome.A retrospective analysis of six consecutive patients who underwent APR due to primary ARMM was performed. Patients were staged by CT and PET/CT.Four out of six patients had preoperative LNM involvement (two patients inguinal and perirectal, one iliacal, one perirectal), with two of them presenting with distant metastases additionally. Inguinal/iliacal LNM in two patients as well as liver metastasis in one patient was seen in PET/CT and missed by CT. The three patients with initial inguinal/iliacal LNM died during the observation period (overall survival: 10 (6-18) months). The three patients without inguinal/iliacal LNM involvement are currently alive, one patient showing a slowly progressive disease since 5 years, and two patients are tumor-free since 8.5 and 1.5 years (the patients had initial perirectal LNM).In ARMM, PET/CT is superior to CT in detection of LNM and distant metastasis. APR is possibly a curative approach if the PET/CT shows exclusively perirectal LNM despite locally advanced tumor growth.

Abdominoperineal resection

Surgical oncology

PET-CT

Distant metastasis

10.1186/s12957-016-0938-x

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Citations (28)

Comparative Analysis of Volatile Constituents from Mice and their Urine

Journal of Chemical Ecology (2006)

Frank Örner -Rock Sven Mueller Udo Weimar Hans‐Georg Rammensee Peter Overath

Decanal

Scent gland

Hexanoic acid

10.1007/s10886-006-9091-2

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Citations (44)

ChemInform Abstract: Benzoazabicyclo[4.3.1] Derivatives by Intramolecular Michael Addition of Piperidinone Enolates to Enoates.

ChemInform (2008)

Gedu Satyanarayana Sven Mueller Martin E. Maier

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Michael reaction

10.1002/chin.200835153

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Oncological outcome of carcinomas in the rectosigmoid junction compared to the upper rectum or sigmoid colon – A retrospective cohort study

European Journal of Surgical Oncology (2019)

Claudius Falch Sven Mueller Manuel Braun Cihan Gani Falko Fend

Rectosigmoid Colon

10.1016/j.ejso.2019.06.024

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Citations (13)