R Tkácová

Hospital Clínic de Barcelona

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Athanasia Pataka

G. Papanikolaou General Hospital

Giedrius Varoneckas

Lithuanian University of Health Sciences

Tarja Saaresranta

Turku University Hospital

A. Vitols

University of Latvia

Ferrán Barbé

Hospital Universitari Arnau de Vilanova

Richard Schulz

Helios Dr. Horst Schmidt Kliniken Wiesbaden

Daniel Rodenstein

Cliniques Universitaires Saint-Luc

W.T. McNicholas

St. Vincent's University Hospital

Carolina Lombardi

IRCCS Istituto Auxologico Italiano

Oreste Marrone

National Research Council

Cooperative Institutions

University of Pavol Jozef Šafárik

Sahlgrenska University Hospital

University of Gothenburg

Turku University Hospital

Charité - Universitätsmedizin Berlin

Democritus University of Thrace

University of Turku

University of Split

University of Crete

Antwerp University Hospital

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[Disorders of lipid metabolism in type 2 diabetics].

PubMed (1992)

G Ivancová R Tkácová I Ivanco

The authors investigated the incidence of different disorders of the lipid metabolism and their age dependence in a group of 67 patients with type 2 diabetes hospitalized at the First Medical Clinic in Kosice. Some disorder of the lipid metabolism was recorded in 67% of the patients. The most frequently encountered disorder was hypertriglyceridaemia (21%). Hypercholesterolaemia was recorded in 16%, combined hyperlipidaemia in 18% and hypoalphalipoproteinaemia in 12% of the patients. Patients with diabetic nephropathy had significantly elevated mean triglyceride levels and reduced HDL-cholesterol levels, as compared with patients without nephropathy. In diabetic women a significantly higher incidence of combined hyperlipidaemias was recorded, as compared with men and the mean total cholesterol and triglyceride levels were also significantly higher in women with type 2 diabetes.

Lipid Metabolism Disorder

Metabolic disorder

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Risk factors for atherosclerosis in female type II diabetic patients with incipient diabetic nephropathy.

PubMed (1992)

Ivan Tkáč A Molcányiová Milena Jadrijević-Mladar Takač R Tkácová E Tomoriova

Microalbuminuria

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Citations (1)

Long-term positive airway pressure therapy is associated with reduced total cholesterol levels in patients with obstructive sleep apnea: data from the European Sleep Apnea Database (ESADA)

Sleep Medicine (2020)

Canan Gündüz Özen K. Başoğlu John A. Kvamme Johan Verbraecken Ulla Anttalainen

Dyslipidemia

Positive airway pressure

10.1016/j.sleep.2020.02.023

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Citations (12)

Hypoxic apnoea induced by N2 inhalation can be reversed by the aspiration reflex in anaesthetized cats

Respiratory Medicine (1991)

Z Tomori Roman Beňačka Viliam Donič R Tkácová

Mydriasis

10.1016/s0954-6111(06)80257-x

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Citations (3)

[Plasma renin activity, creatinine and uric acid in the serum of patients with essential hypertension].

PubMed (1990)

M Pjescák I Suchmanová J Mechír R Tkácová E Rajnová

The authors examined the plasma renin activity (PRA), serum uric acid and creatinine in 53 patients with essential hypertension (EH). They recorded low renin EH in 28%, normorenin EH in 53% and high-renin EH in 19% of the hypertensive patients. Assessment of basal PRA levels does not suffice for the classification of EH because the PRA response after stimulation is not related to its basal values. The authors found significantly higher levels of serum creatinine in low-renin EH. They did not confirm a relationship between PRA and the uric acid serum level in any form of EH.

Plasma renin activity

Essential hypertension

Basal (medicine)

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[Plasma renin activity and aldosterone in patients with essential hypertension].

PubMed (1990)

I Suchmanová M Pjescák Ivan Kron R Tkácová B Grejtovská

The authors examined the plasma renin activity (PRA) in 80 patients and plasma aldosterone (PA) in 27 patients with essential hypertension (EH). They confirmed the significant drop of stimulated PRA with age. The PA levels of hypertonic patients did not change with age and did not change significantly in relation to PRA. In obese hypertonic patients a satisfactory response of PRA to stimulation was lacking, while PA reacted adequately. The PA levels are thus in older age groups as well as in obese subjects much higher, as compared with relatively low PRA levels. In relation to the stage of EH the authors did not find any significant differences of PRA levels.

Plasma renin activity

Essential hypertension

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Use of the Clinical Global Impression scale in sleep apnea patients – Results from the ESADA database

Sleep Medicine (2018)

Marijke Dieltjens Johan Verbraecken Jan Hedner Olivier M. Vanderveken Paschalis Steiropoulos

Epworth Sleepiness Scale

Clinical Global Impression

10.1016/j.sleep.2018.10.028

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Citations (15)

[Factors affecting serum lipid levels in patients with type 2 diabetes mellitus].

PubMed (1994)

Ivan Tkáč R Tkácová A Molcányiová Tania Mudrikova Milena Jadrijević-Mladar Takač

Serum lipid concentrations were assessed in 147 type 2 diabetics. The patients were divided into different sub-groups in order to follow up different factors which could have an impact on serum lipids. The mean total cholesterol concentrations were significantly higher in diabetic women as compared with men. The authors did not reveal significant differences in lipid concentrations between obese and non-obese diabetics. Hypertensive diabetics had higher mean total cholesterol levels and LDL-cholesterol levels, as compared with diabetic patients without hypertension. Patients using oral antidiabetics had significantly higher mean triglyceride levels and lower HDL-cholesterol levels, as compared with insulin-treated diabetics. In a multiple stepwise regression analysis correlated triglycerides with three independent variables: total cholesterol, diastolic blood pressure and inversely with HDL-cholesterol. On the other hand, total cholesterol correlated significantly with triglycerides, HDL-cholesterol and proteinuria/day. To sum up, it may be stated, that the results of the present investigation are consistent with Reaven's concept of the syndrome X, however the cholesterol concentration is affected also by the proteinuria.

Stepwise regression

Lipid Profile

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