A. Bischof-Delaloye

Research Field

Clipping (morphology)

Vena cava

10.1177/000331978203300703

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Ectopic ACTH Cushing’s Syndrome: V3 Vasopressin Receptor But Not CRH Receptor Gene Expression in a Pulmonary Carcinoid Tumor

Hormone Research in Paediatrics (1998)

V. Chabot Yves de Keyzer Sandra Gebhard A Uské A. Bischof-Delaloye

In the etiological diagnosis of ACTH-dependent Cushing’s syndrome, it may be difficult to distinguish pituitary disease from ectopic ACTH production, specially when this is due to a benign neuroendocrine tumor. We describe a patient with partial dexamethasone suppression consistent with Cushing’s disease, an absent response to CRH suggesting ectopic ACTH production and an atypical, apparent circadian rhythm. Bilateral cavernous sinus catheterization suggested a nonpituitary source of ACTH and, in the search of an ectopic tumor, somatostatin receptor scintigraphy, abdominal CT scan, and duodenopancreatic endoscopic echography were performed and failed to reveal any abnormality. Thoracic CT scan disclosed a tiny right lung nodule that showed a definite tracer uptake on MIBG scintigraphy. After resection, the nodule proved to be an 8-mm typical pulmonary carcinoid, with positive immunostaining for the classical neuroendocrine markers and for ACTH, and showing tissue expression of the POMC gene. However, the CRH receptor gene was not expressed, explaining the absent CRH response in vivo, whereas the V3 vasopressin receptor gene was expressed in the tumor tissue. The latter feature appears to be characteristic of benign carcinoids and may contribute to explaining the CRH-independent circadian rhythm observed in this case.

Cushing's disease

10.1159/000023279

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Citations (14)

Circulating CD26 Is Negatively Associated with Inflammation in Human and Experimental Arthritis

American Journal Of Pathology (2005)

Nathalie Busso Nicolai Wagtmann Christian Herling Véronique Chobaz-Péclat A. Bischof-Delaloye

Dipeptidyl peptidase

Proinflammatory cytokine

10.1016/s0002-9440(10)62266-3

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Citations (199)

Left bundle branch block (LBBB) and coronary artery disease (CAD): Accuracy of dipyridamole in case of positive stress Thallium-201 SPECT

Journal of Nuclear Cardiology (1995)

N. -E. Lebtahi J. C. Stauffer A. Bischof-Delaloye L Kappenberger B Delaloye

Dipyridamole

Thallium

Bundle branch block

10.1016/s1071-3581(05)80214-4

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Localization of radiolabelled monoclonal anti-CEA antibodies and fragments in colon carcinoma, — diagnostic and therapeutic approaches

European Journal of Cancer and Clinical Oncology (1987)

J.-P. Mach A. Bischof-Delaloye B Delaloye

Colon carcinoma

10.1016/0277-5379(87)90640-7

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Effect of age and menopausal status on indices of coronary vasomotion in women without coronary risk factor

Journal of Nuclear Cardiology (2005)

John O. Prior Alvaro D. Facta Thomas H. Schindler Maria Angela Oxilia-Estigarribia Miguel Hernandez‐Pampaloni

Vasomotion

10.1016/j.nuclcard.2004.12.266

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Esophageal and Pulmonary Scintiscanning in Gastroesophageal Reflux in Children

Progress in pediatric surgery (1985)

Dara S. Berger A. Bischof-Delaloye Olivier Reinberg M. Roulet

Esophagitis

Pulmonary aspiration

Reflux esophagitis

10.1007/978-3-642-70276-1_9

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Citations (6)

90Y-Ibritumomab Tiuxetan (Zevalin®) Consolidation of First Remission in Advanced Stage Follicular Non-Hodgkin’s Lymphoma: First Results of the International Randomized Phase 3 First-Line Indolent Trial (FIT) in 414 Patients.

Blood (2007)

Anton Hagenbeek A. Bischof-Delaloye John Radford A. Z. S. Rohatiner Gilles Salles

Ibritumomab tiuxetan

Follicular lymphoma

Tolerability

Clinical endpoint

Surrogate endpoint

10.1182/blood.v110.11.643.643

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Citations (35)

Sequential and regional renal quantitative exploration

B Delaloye A. Bischof-Delaloye C. Beckers

Source

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Radionuclide investigations of the urinary tract in the era of multimodality imaging.

PubMed (2006)

Ariane Boubaker John O. Prior Jean‐Yves Meuwly A. Bischof-Delaloye

This article presents the role of nuclear medicine procedures in investigating renal and parenchymal disease, as well as upper urinary tract abnormalities. More specifically, the use of scintigraphy is described in the exploration of urinary tract dilatation and UTIs, vesicoureteric reflux, renovascular hypertension, and renal transplants. With a low radiation burden and the absence of sedation, these nuclear medicine procedures are easy to perform and can provide clinicians with valuable data on renal perfusion and the function of individual kidneys, as well as on urinary tract dynamics. However, knowledge of limitations and technical pitfalls is essential in understanding the role of scintigraphy among contemporary imaging methods and the unique information it supplies in nephrourology.

Renovascular Hypertension

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Citations (48)

A. Bischof-Delaloye

Papers

Citation

H-Index

i-10 index

Papers

Citation

H-Index

i-10 index