Takako Kawai

Momoyama Gakuin University

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Kenji Tani

Yamaguchi University

Takao Okubo

Saiseikai Ibaraki Hospital

Keiichiro Matsunaga

Naval Hospital Yokosuka Japan

Kiyoshi Katoh

Tohoku University Hospital

Yoshiaki Ishigatsubo

Yokohama City University

Nagato Natsume

Aichi Gakuin University

Masahiro Narita

Public Health – Seattle & King County

K Katoh

Toyo University

Akiko Aoki

Tokyo Medical University Hachioji Medical Center

Ikunosuke Sakurabayashi

Jichi Medical University

Cooperative Institutions

Yokohama City University

Osaka University

Aichi Gakuin University

Kyoto University

The University of Tokyo

Tohoku University

Osaka University of Pharmaceutical Sciences

Hiroshima University

Nihon University

Okayama University

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[Quantitative measurement of rheumatoid factor (RF) by turbidimetric immunoassay (TIA)--methodological and clinical investigations].

PubMed (1987)

Naofumi Mukaida Ikunosuke Sakurabayashi Hidehiko SHIBATA Shinichi Hirose Takeshi Azuma

Rheumatoid factor

Turbidimetry

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Relationships between self-efficacy on health behavior and patient's assessment of rheumatoid arthritis conditions

An Official Journal of the Japan Primary Care Association (2013)

Akiko Aoki Akiko Suda Syohei Nagaoka Mitsuhiro Takeno Yoshiaki Ishigatsubo

目的 : 関節リウマチ (RA) 患者の健康行動に対する自己効力感と患者の疾患評価との関連を明らかにする.対象 : 都市部3病院のRA専門外来に3カ月以上通院している成人RA患者.方法 : 無記名自記入式質問紙法による連続性サンプリング横断的調査研究を2010年10～12月に実施した. 自己効力感の測定には「慢性疾患患者の健康行動に対する自己効力感尺度 Chronic disease-self efficacy scale (CD-SES) 」を用いた. CD-SESは対処行動の積極性14項目 (積極性) と健康に対する統制感10項目 (統制感) の2つの下位尺度で構成される. 患者による疾患の評価として, 疼痛関節数, 腫脹関節数, 最近の血清CRP, 全般的な体の調子, 日常生活動作 (ADL) の障害度を質問した.結果 : CD-SES24項目に回答した191人の回答を解析した. CD-SES全体は高齢者ほど, 全般的な体の調子が良く, ADLの障害が少ないほど高値であった. 積極性は高齢者ほど, 統制感は全般的な体の調子が良いほど高値であった.結語 : RA患者の健康行動に対する自己効力感は, 年齢, 全般的な体の調子やADLの障害度と相関することが示された, 心理的なサポートが統制感を含む自己効力感を改善し, 全般的な体の調子を改善することができるか, 今後縦断的な研究が必要と考えられた.

10.14442/generalist.36.308

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[Investigation of plasma levels of etodolac and urine PGE2 in patients with rheumatoid arthritis].

PubMed (1999)

Keiichiro Matsunaga Makoto Yawata Natsuko Hagiya Kenji Tani Takako Kawai

13 women patients (containing high-aged, mean age 71.9 years) with rheumatoid arthritis (RA) (10 with normal renal function and 3 with moderate renal insufficiency) participated in a 5-day study to assess the effects of etodolac on renal function and the necessity of dose adjustment. After no drug-free day, etodolac, 200 mg b.i.d. was started. The plasma levels of etodolac were similar in both normal control in phase I studies and throughout this study. Although the mean urine PGE2 concentration in renal insufficient group was significantly lower than that of normal renal function group, the mean urine PGE2 concentration in after etodolac administration was not different from that in before its administration in each group. This result suggested that renal adverse reactions with etodolac were low in incident. Moreover, it was required to consider that glucocorticoid might influence renal and/or hepatic excretion of etodolac. In this study the glucocorticoid was tend to be administrated in the patients with moderate renal insufficiency. Those glucocorticoid group showed lower levels of etodolac in blood serum (monitored by AUC0-8, day 4 Cmin and day 5 Cmin) than non-glucocorticoid group did, but not significantly. Interestingly, there is a negative correlation (r = -0.442) between AUC0-8 at day 1 and urine PGE2 at day 5 in glucocorticoid group. The levels of etodolac in blood serum in normal renal function group were also not significant in difference from that in the moderate renal insufficient group. These results suggest that the dose adjustment of etodolac in high-aged RA patients with moderate renal insufficiency can be excluded.

Etodolac

Cmin

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The Custom and Disrtribution of Rice Gruel of Tea in Kyoto, Osaka, Mie, Nara and Wakayama Prefecture

Journal for the Integrated Study of Dietary Habits (2000)

Fumiko Hayakawa Akiko Maeda Miyuki Minami Takako Kawai Sachiko Fuzisawa

There are the reports the custom of eating rice gruel made with tea mainly on Western Japan. But its details are not clarified. In order to clarify the eaten reason and origin of it, the range of its custom and distribution in Kyoto, Osaka, Mie, Nara, and Wakayama prefecture in 1999 is investigated by Questionnaire. The Questionnaire was distributed to dietitians (age20-70) living in each area.1) The custom of eating rice gruel made with tea is distributed especially on the border of the prefectures, and also in the seaside districts of Wakayama and Osaka prefectures.2) Next to Wakayama prefecture, Nara prefecture has the most rice gruel made with tea, however this custom in all of them is on the decrease.3) Rice gruel made with tea is called Tyagayu rather than Okaisan by Osaka and Mie prefectures, but called Okaisan by Wakayama prefecture.4) The common materials added to rice gruel made with tea in the five areas are sweet potato, rice cake, and adzuki beans.5) The reason that the custom of eating rice gruel made with tea remains today is that it tastes good.

10.2740/jisdh.11.259

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[A case of surgical correction using both the Wassmund-Wunderer method and step-ostectomy for mandibular mobilization in open bite].

PubMed (1983)

Y Kumaxawa Isamu Nitta K Mashiko Midori Ohshima Takako Kawai

Ostectomy

Mobilization

Open bite

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A case of leiomyoma in the left cheek

Japanese Journal of Oral & Maxillofacial Surgery (1973)

Takako Kawai Hiroshi Inamoto Shinobu NISHO Yoshiki Takai Masahiko FUKAYA

Cheek

10.5794/jjoms.19.385

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A case of systemic lupus erythematosus after taking oral contraceptives.

Nihon Naika Gakkai Zasshi (1989)

Takako Kawai Kiyoshi Katoh Keiichiro Matsunaga Kenji Tani Takao Okubo

In December, 1986, a 29 year old woman developed nephrosis due to systemic lupus erythematosus after taking oral contraceptives (OC) for 6.5 years. Hospitalized for 3 months, she received steroid treatment, which lowered albumin in urine. At the time of hospitalization, the following symptoms were noted. Edema on all her limbs, 4.5 g/dl of urine albumin per day, white blood cell count of 2600/mm, 640 time positive anti-nuclear antibodies, pseudo-positive response to syphilis via bentonite flocculation on particle (BFP). OC she had taken since 1980 were 0.5 mg of norgestrel day and 0/05 mg of ethinyl estradiol day. She had been routinely checked on her kidney function biannually and everything had been normal till then. For 2 months starting in December, 1987, at the patient's request, progesterone along (dydrogesterone 10 mg/day) was administered for contraception. No urine albumin was detected. It appears that autoimmune-type thyroid gland abnormality preceded systemic lupus erythematosus (SLE) which was triggered by the oral contraceptive use. Estrogen metabolism of SLE patients is characterized by estrogen active 16 alpha hydroxyestrone.

10.2169/naika.78.710

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Citations (2)

Case control study of cleft lip and/or palate (CL/P) — Maternal effect and the development of CL/P among Japanese

International Journal of Oral and Maxillofacial Surgery (1997)

Nagato Natsume Takako Kawai G. Kohama Shinji Itoh Tathyane Harumi Nakajima Teshima

10.1016/s0901-5027(97)80963-0

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BENEFICIAL EFFECT OF ORAL MESALAZINE POWDER ADMINISTRATION ON GASTRIC INVOLVEMENT OF BEHÇET's DISEASE

Digestive Endoscopy (2005)

Reiko Kunisaki Takako Kawai Makiko Shiozawa Fumio Suzaki Masaru Naitoh

Behçet's disease (BD) is a multisystem immune‐mediated inflammatory disorder that involves the gastrointestinal tract. Although intestinal BD chiefly affects the ileocecum and colon, it may involve the entire alimentary tract. Upper gastrointestinal involvements of BD are not common, and its treatment has been rarely reported. Mesalazine is known to be an effective anti‐inflammatory agent for treatment of distal intestinal lesions of inflammatory bowel disease by its delayed drug release system. Here we show a case of chronic active, steroid‐dependent BD involving the upper gastrointestinal tract who was treated with ground mesalazine powder. Endoscopy performed 8 weeks after the treatment showed marked improvement of the gastric ulcers. This is the first report of intestinal BD treated with oral administration of mesalazine powder, and our results suggest that it may be a beneficial and effective new therapy for the upper gastrointestinal lesion of BD.

Mesalazine

10.1111/j.1443-1661.2005.00537.x

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[Clinical significance of alpha 2-macroglobulin analysis in biochemical laboratory tests].

PubMed (1989)

H Noghuchi Takako Kawai

Alpha (finance)

alpha-2-Macroglobulin

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