Hideo Tateishi

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A patient with hepatic granuloma formation and angiotensin‐converting enzyme production by granuloma cells during clinical relapse of hepatitis A

Pathology International (1994)

Sadataka Inuzuka Takato Ueno Hideo Tateishi Takuji Torimura Michio Sata

Elevation of the serum angiotensin‐converting enzyme (sACE) level and hepatic granulomas were found during a clinical relapse in a 22 year old patient with acute viral hepatitis type A (AVH‐A). The serum transaminase level and sACE level remained high for more than 6 months. In the biopsied specimen of the liver, fibrous rings of granulomas composed of collagen types I, III, and V were observed. Furthermore, the localization of ACE was visible in the rough endoplasmic reticulum of epithelioid cells of granulomas in the liver under electron microscopy using the indirect immunoperoxidase method. These results suggest that granuloma cells in the liver caused by hepatitis A may be involved in ACE production. In addition, other diseases associated with the presence of granulomas in the liver, such as lymphoma, cytomegalovirus infection, visceral leishmaniasis, and lupoid hepatitis, were ruled out. However, the hepatic granulomas disappeared with the healing of AVH‐A. In this regard, the present case is considered to be one of the very few cases of hepatic sarcoidosis.

Immunoperoxidase

10.1111/j.1440-1827.1994.tb02940.x

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Citations (3)

A Case of Left-sided Gallbladder Combined with an Anomalous Intrahepatic Portal Vein, Confirmed by Laparoscopic Cholecystectomy.

The Japanese Journal of Gastroenterological Surgery (1996)

Shuji Takiguchi Mitsugu Sekimoto Shigeo Matsui Hiroshi Yano Hideo Tateishi

副肝管および肝内門脈分枝異常を伴った左側副胆嚢を腹腔鏡下に摘出した症例を経験した. 症例は41歳の女性. 平成6年6月, 胆石症にて腹腔鏡下胆嚢摘出術を施行した. 胆嚢は胆嚢窩が肝円索の左側に位置する左側胆嚢で, 肝内門脈分枝異常および副肝管を合併していた. 胆道系の先天性異常のなかで内臓逆位を伴わず, 胆嚢索の左側に位置する左側胆嚢のわが国における報告例は50例と非常にまれである. この中に自験例のごとく肝内門脈分枝異常を合併した症例が, 9例と高率に認められている. 右臍静脈が残存し右肝円索を形成した場合, 胆嚢床が肝円索の左側に形成される可能性が考えられる. このような発生過程は, 肝円索の走行異常による左側胆嚢で, 従来考えられてきた発生機序とは異なるものと考えられた. 我々が経験した症例について報告し文献的考察をおこなった.

10.5833/jjgs.29.2294

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Citations (6)

The usefulness, indications, and complications of laparoscopy-assisted colectomy in comparison with those of open colectomy for colorectal carcinoma

Surgery Today (2000)

Shigeru Marubashi Hiroshi Yano Takushi Monden Taishi Hata Hidenori Takahashi

Colorectal Surgery

Surgical oncology

10.1007/s005950070113

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Citations (39)

3-Dimensional Images Processed by Multislice CT was Efficacious to Determine the Suitable Hepatectomy for a Case of Liver Metastasis of Colon Cancer.

The Japanese Journal of Gastroenterological Surgery (2002)

Masaru Murata Shigeyuki Yoshida Misako Yamagata Hideo Tateishi Masaaki Motoori

マルチスライスCTより作成した3次元画像が術式決定に有用であった大腸癌肝転移の1例を報告する. 症例は63歳の男性. 他院で下行結腸癌の手術を受け経過観察中, 肝転移を指摘され当院を受診した. 肝CT水平断像で腫瘍はS3を中心にS4に進展しており, 左葉切除が必要であると考えられた.CT肝動脈造影検査で左肝動脈は左胃動脈より分枝し, これが腫瘍に流入していることが示された.CT門脈造影検査では, 腫瘍は門脈P3本幹と離れていることが示された. 以上より左肝動脈を切離の後, 門脈P3本幹を温存したS3部分切除が妥当であると判断され, これらの画像に推奨された手術が可能であった. 近年, 低侵襲で多くの情報が得られるマルチスライスCTが普及しつつあるが, 肝臓外科領域での有用性についてはあまり報告されていない. 本症例に肝切除を行うに際して, マルチスライスCT は適切な術式の決定に有用であった.

Multislice

Liver Cancer

10.5833/jjgs.35.1726

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Loss of genes on chromosome 22 in medullary thyroid carcinoma and pheochromocytoma.

Shin‐ichiro Takai Hideo Tateishi Isamu Nishisho Tetsuro Miki Kazuyoshi Motomura

Using polymorphic DNA markers, we compared the constitutional and tumor genotypes of patients with multiple endocrine neoplasia type 2A (MEN2 A). We found loss of constitutional heterozygosity at the D22S9 locus in one out of 9 medullary thyroid carcinomas (MTCs). No loss of heterozygosity was detected at 12 other loci in any of the MTCs tested. Loss of heterozygosity at D22S9 and/or D22S1 was also demonstrated in 2 out of 5 pheochromocytomas tested. These results suggest that loss or mutation of a gene on chromosome 22 may play an important role in tumorigenesis in MEN2A.

Medullary carcinoma

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Immune-mediated Drug-induced Liver Injury Caused by Laninamivir Octanoate Hydrate

Internal Medicine (2019)

Toshihiro Kawaguchi Teruko Arinaga‐Hino Motoki Shimizu Ken Tanikawa Takahiko Tokushige

We herein report the first case of immune-mediated drug-induced liver injury that may have been caused by laninamivir. A 15-year-old girl was diagnosed with influenza and prescribed 40 mg laninamivir. Six weeks later, she was admitted to our hospital because of jaundice and fatigue. Laboratory examinations revealed elevated levels of hepatobiliary enzymes, and acute liver injury was suspected. Laboratory examinations and histological findings were characteristic of autoimmune hepatitis. Steroid treatment was ineffective, and azathioprine was added to the treatment. Twenty-two months after the onset, a second biopsy revealed the absence of inflammatory infiltrations, and the drugs were withdrawn. Liver function tests remained normal nine months after withdrawal.

Autoimmune Hepatitis

Toxic hepatitis

10.2169/internalmedicine.2740-19

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Citations (3)

LAPAROSCOPY-ASSISTED PROCTOCOLECTOMY FOR FAMILIAL ADENOMATOUS POLYPOSIS

Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) (1998)

Shuji Takiguchi Hirohide Maruyama Hiroshi Yano Mitsugu Sekimoto Eiji Taniguchi

We report a case of familial adenomatous polyposis with an advanced cancer of the sigmoid colon which was treated with laparoscopic surgery. A 36-year-old woman was pointed out to have a familial adenomatous polyposis with a signoid colon cancer by a barium contrast study of the colon. an operation was conducted through four 10-mm trocars. the total colon was laparoscopically dissected and mobilized from the abdominal wall and retroperitoneum. the root of the inferior mesenteric artery was exposed. The total colon was extracted through a 9cm lower abdominal midline incision. The gastrocolic ligament and right side of the mesocolon were incised. Lymph node dissection of the inferior mesenteric artery was perfromed through the incision. The lower recutm was dissectd through the incision. the total colon was removed through the incision after transcetion of the rectum and ileum. heal-reservoir (J-pouch9 and anal anastomosis were performed. The operation time was 6 hours and 34 minutes. Postoperative course was uneventful. As three months after the surgery, anal function has been good and the patients has bowel movements 3 or 4 times a day.

Inferior mesenteric artery

Proctocolectomy

10.3919/jjsa.59.724

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A CASE OF ENTERIC TUBERCULOSIS PRESENTED WITH COLORECTAL BLEEDING WITH DIFFICULTIES IN DIAGNOSIS AND TREATMENT

Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) (2006)

Toru Masuzawa Takayuki Fukuzaki Kunitaka Shibata S. Tominaga Hideo Tateishi

今回われわれは診断治療に難渋した腸結核の1例を経験したので,これを報告する.症例は57歳,男性で,平成17年2月より食欲不振が出現し,胃潰瘍の診断にて当院内科外来に通院していた. 4月28日に下血を認め,下部消化管内視鏡を施行したところ,回盲部に全周性病変を認め,大腸癌と診断した.同部より出血を認め,内視鏡的に止血を行った.下血が続くため,腹部血管造影を施行すると,回腸に別の出血点を認め, 5月8日緊急手術となった.病変は盲腸と終末回腸2箇所の合計3箇所に認めた.リンパ節も腫大しており,悪性リンパ腫を疑ったが,術後病理にてリンパ節に乾酪壊死とLanghans型巨細胞を認め,腸結核と判明した.腸結核は多くは肺結核からの感染といわれている.近年結核罹患率は減少傾向ではあるが,肺結核を伴わない原発性腸結核の報告もしばしばみられ,腸結核の存在を念頭においた診療が必要である.

Langhans giant cell

INTESTINAL TUBERCULOSIS

10.3919/jjsa.67.1028

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Citations (1)

LAPAROSCOPY ASSISTED RIGHT HEMICOLECTOMY FOR AN ADVANCED ASCENDING COLON CANCER

The journal of the Japanese Practical Surgeon Society (1994)

Mitsugu Sekimoto Masakatsu Kinuta Hideo Tateishi Junkou Furukawa Hirohide Maruyama

The present paper deals with the successful laparoscopy assisted right hemicolectomy performed for a patient of advanced ascending colon cancer. The patient was a 65-year-old woman, who visited the hospital complaining of anemia, and was diagnosed as having an ascending colon cancer by studies of barium enema. The operation was performed by abdominal wall lifting method, without peritoneal insufflation, through 4ports and 6cm of right trans rectal incision. Mobilization of the bowel was performed laparoscopically, lymph nodes at the root of the mesenterium were dissected through the incision, and the ileo-colic end to end anastomosis was performed extracorporeally. Total operating time was 330 minutes, blood loss amount was 120g. Postoperative course was uneventful, and the passage of flatus appeared at 2nd day postoperatively. In Japan, indication of laparoscopy assisted colon operation is confined only to the cases of both early cancer and benign diseases, for it is, technically, not feasible to dissect lymph nodes laparoscopically. We performed right hemicolectomy with dissection of lymph nodes at the root of the mesenterium, just as the same as performed routinely in open laparotomy, through the small incision so that the specimen could be excised extracorporeally. We conclude that the curative operation for the ascending colon cancer can be performed laparoscopically by our techniques.

Right hemicolectomy

Ascending colon

Hemicolectomy

10.3919/ringe1963.55.2350

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Erythropoietin production in hepatocellular carcinoma cells associated with polycythemia: Immunohistochemical evidence

Hepatology (1993)

Shotaro Sakisaka Masahide Watanabe Hideo Tateishi Masaru Harada Satoshi Shakado

Patients with hepatocellular carcinoma sometimes have erythrocytosis and high plasma erythropoietin levels. However, previous studies have not revealed direct evidence that the carcinoma cells produce the erythropoietin. To address this question, we carried out light and electron microscopic immunohistochemical studies, using a human erythropoietin antibody to the liver in three male patients with hepatocellular carcinoma and erythrocytosis. alpha-Feto-protein localization was also examined in serial liver sections by light microscopic immunohistochemistry with an antibody to alpha-fetoprotein. All three patients demonstrated high hemoglobin levels (16.7, 17.6 and 18.1 gm/dl) and high plasma erythropoietin levels (227, 266 and 280 mU/ml). In one patient the plasma erythropoietin level in the hepatic vein was significantly higher than that in the hepatic artery. The levels of plasma erythropoietin, as well as such tumor markers for hepatocellular carcinoma as serum alpha-fetoprotein and plasma des-gamma-carboxyprothrombin, were significantly reduced after treatment with an anticancer drug, cisplatin. Light microscopic immunohistochemistry showed that erythropoietin was definitely present in the cytoplasm of the hepatocellular carcinoma cells, but not in normal hepatocytes around the carcinoma lesion or in other nonparenchymal cells such as vascular endothelial cells and Kupffer cells. In electron microscopic immunohistochemistry, reaction products for erythropoietin were revealed in the cisternae of the endoplasmic reticulum in the carcinoma cells, suggesting the production of erythropoietin by these cells. Light microscopic immunohistochemistry showed that alpha-fetoprotein was localized in the hepatocellular carcinoma cells that were erythropoietin positive in the serial sections. These findings indicated that hepatocellular carcinoma cells produced erythropoietin as well as alpha-fetoprotein in these cases, leading to the complication of erythrocytosis.

10.1002/hep.1840180612

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Citations (55)