J. Munoz- Gomez

Universitat de Barcelona

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Anna Ribera

Galapagos (Belgium)

Carlos Piera

Hospital Clínic de Barcelona

J. Setoain

Hospital Clínic de Barcelona

Margarita M. Navia

Instituto Nacional de Saúde

Jordi Gratacós

Universitat Autònoma de Barcelona

Antoni Gayá

Banc de Sang i Teixits

F. Lomeña

Universitat Internacional de Catalunya

Jordi Vilà

Universitat de Barcelona

Mayte Blay

Universidad Rovira i Virgili

Josep Mensa

Consorci Institut D'Investigacions Biomediques August Pi I Sunyer

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Hospital Clínic de Barcelona

Universitat de Barcelona

Consorci Institut D'Investigacions Biomediques August Pi I Sunyer

Universitat Autònoma de Barcelona

Banc de Sang i Teixits

Center for Rheumatology

Barcelona Institute for Global Health

Fundació Clínic per a la Recerca Biomèdica

Digestive Health Research Institute

Biomedical Research Institute

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CORRELATION BETWEEN PSEUDOSPONDYLOLISTHESIS AND ARTHROSIS OF THE HANDS

Lara D. Veeken (1977)

J. Munoz- Gomez M. A. BRANCOS CUNILL Jaime Rotés Querol

Two groups of 25 patients, one with pseudospondylolisthesis (PSL) and the other without, have been compared in order to verify the impression that arthrosis of the hands occurs more frequently in those with PSL. The observed differences were significant, being especially marked in women in whom five or more hand joints were involved and increasing in frequency with age. No relation was found between PSL and either discarthrosis or being overweight. The presence of PSL can probably be included in the pattern of generalized osteoarthrosis described by Kellgren and Lawrence (1958).

PSL

10.1093/rheumatology/16.1.30

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Citations (3)

Comparative cytokine gene expression in synovial tissue of early rheumatoid arthritis and seronegative spondyloarthropathies

Lara D. Veeken (1997)

Juan D. Cañete J. F. Llena Antonio Collado Raimón Sanmartí Antoni Gayá

Interleukin 1-beta (IL-1 beta), IL-2, IL-4, IL-5, IL-6, IL-8, tumour necrosis factor-alpha (TNF-alpha), transforming growth factor-beta (TGF-beta) and granulocyte-macrophage colony-stimulating factor (GM-CSF) gene expression was determined in knee synovium of 16 patients with rheumatoid arthritis (RA) and 16 patients with seronegative spondyloarthropathies (SSP), by using polymerase chain reaction (PCR) amplification. The pattern of cytokines observed in RA synovium is of the macrophage-fibroblast type, with the highest expression of IL-1 beta and TGF-beta. GM-CSF and IL-2 bands were visualized in a minority of patients. Neither IL-4 nor IL-5 could be detected. No significant differences were observed in the cytokine profile between patients with early (< 12 months) and more advanced disease. No differences were observed according to gender, age, rheumatoid factor status and the duration of knee synovitis. The pattern of cytokines in the synovium of SSP patients is similar to that observed in RA patients and does not change in relation to disease duration. IL-2 was the only T-cell cytokine observed. These data provide evidence that the macrophage-fibroblast cells have an important role in early and more advanced rheumatoid synovitis, and show that this is also true for SSP peripheral synovitis.

10.1093/rheumatology/36.1.38

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Citations (60)

[The gammagraphic diagnosis of dialysis-associated amyloidosis with beta 2-microglobulin-I-131. Preliminary results].

PubMed (1990)

E Ponz Carlos Piera Josep M. Campistol F. Lomeña Arturo García Pavía

Beta-2 microglobulin

BETA (programming language)

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Amiloidosis