ToneJet is a powerful digital printing technology which establishes new standards of performance and quality. This paper represents the first public presentation by ToneJet Limited. It describes some key aspects of the technology, its high quality output, and its applications in production printing.
The structures of the major merozoite surface antigen of Plasmodium falciparum and the gene encoding it were indistinguishable for the Wellcome strain and the Thai clone T9/94 but different for clones T9/96, T9/98, and T9/101. The central portion of the gene is subject to the greatest variation in structure. The protein from all five lines was found to be posttranslationally modified by covalent addition of both carbohydrate and fatty acid.
The clinical, angiographic, and Doppler findings are reported for two young patients with recurrent syncope induced by neck hyperextension during stretching. Transcranial Doppler monitoring of both posterior cerebral arteries was performed during head manoeuvres. There were reproducible rapid decreases in blood flow velocities in both patients to an average of 28% and 41% of baseline values when they performed neck hyperextension. These decreases were regularly associated with the patients9 symptoms and were not found during rotation or flexion. On return to a neutral head position there was a transient increase of the blood flow velocities to an average of 131% and 136% of baseline values (reactive hyperaemia). Routine four vessel angiography was normal except for the demonstration of very small posterior communicating arteries in one patient. Dynamic angiography showed evidence of extracranial compression of the craniocervical arteries in both patients. It is concluded that decreased blood flow to the posterior circulation is an important factor in the pathogenesis of adolescent stretch syncope.
Summary Two proteins produced in recombinant Escherichia coli and containing ammo acid sequences from the Plasmodium falciparum precursor to major merozoite surface antigens (PMMSA) have been partially purified. These proteins, together with a preparation of merozoites, have been used to immunize animals. The antibody response and the degree of protection were compared. Animals immunized with merozoites produced antibodies reacting with many P. falciparum proteins. whereas a response specific for PMMSA was detected in those receiving the recombinant material. Incomplete protection was conferred to both groups and there was no apparent correlation between antibody levels and protection.
Endovascular repair of the traumatically injured thoracic aorta has emerged as an exceptionally promising modality that is typically quicker than open repair, with a reduced risk of paralysis. There is a specific set of anatomic criteria that need to be applied, which can be rapidly assessed by the CT angiogram. The enthusiasm for endovascular repair must be tempered by recognition of the complications and lack of long-term follow-up, particularly in younger patients. Surgeons who are skilled in open aortic repair must not only be involved, but should take on a leadership role during the planning, deployment, and follow-up of these patients. As more specific devices become available, and more follow-up is accrued, the role of endovascular stents will continue to grow. Endovascular repair of the traumatically injured thoracic aorta has emerged as an exceptionally promising modality that is typically quicker than open repair, with a reduced risk of paralysis. There is a specific set of anatomic criteria that need to be applied, which can be rapidly assessed by the CT angiogram. The enthusiasm for endovascular repair must be tempered by recognition of the complications and lack of long-term follow-up, particularly in younger patients. Surgeons who are skilled in open aortic repair must not only be involved, but should take on a leadership role during the planning, deployment, and follow-up of these patients. As more specific devices become available, and more follow-up is accrued, the role of endovascular stents will continue to grow.
It is our belief that any abnormality in keratinization is secondary to an increased rate of epidermal cell production and decreased transit time and research into the underlying nature of psoriasis should concentrate on the issue of whether the stimulus to increased epidermopoietic activity is dermally or epidermally derived.