İB

İsmail Bıyık

Usak University

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İF

İbrahim Faruk Aktürk

Burdur Mehmet Akif Ersoy Üniversitesi

Nilgün Işıksaçan

Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi

Fatma Nihan Turhan Çağlar

Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi

Mehmet Ertürk

Burdur Mehmet Akif Ersoy Üniversitesi

Ahmet Arif Yalçın

Burdur Mehmet Akif Ersoy Üniversitesi

Fatih Uzun

Burdur Mehmet Akif Ersoy Üniversitesi

ÖÇ

Ömer Çelik

Burdur Mehmet Akif Ersoy Üniversitesi

Serkan Yazan

Burdur Mehmet Akif Ersoy Üniversitesi

Selçuk Opan

Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi

Mehmet Rıfat Yildirim

Burdur Mehmet Akif Ersoy Üniversitesi

Cooperative Institutions

Burdur Mehmet Akif Ersoy Üniversitesi

Sağlık Bilimleri Üniversitesi

Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi

University of Health Science

Istanbul University

University of Health Sciences

Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi

İstanbul Eğitim ve Araştırma Hastanesi

Usak University

Institute of Cardiology

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PP-014 THE EFFECT OF RAMADAN FASTING ON BLOOD PRESSURE LEVELS OF HYPERTENSIVE PATIENTS WITH COMBINATION THERAPY

International Journal of Cardiology (2012)

İbrahim Faruk Aktürk İsmail Bıyık Cüneyt Koçaş S. Yalçin Fatih Uzun

10.1016/s0167-5273(12)70251-6

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Citations (3)

Can thrombectomy and catheters used increase angiographically visible distal embolization in ST elevation myocardial infarction?

Archives of Medical Science - Atherosclerotic Diseases (2016)

Çetin Sarıkamış Nihan Turan Caglar İsmail Bıyık Derya Öztürk Fatih Uzun

Primary percutaneous coronary intervention (PPCI) is the preferred treatment of ST segment elevation myocardial infarction (STEMI). Manual thrombectomy catheters developed to prevent distant embolization are theoretically attractive; however, their clinical efficacy remains controversial. The effects of manual thrombectomy catheters on angiographically visible distal embolisation (AVDE) have not been studied so far. The aim of this study was to evaluate the effects of manual thrombectomy during PPCI on AVDE and to investigate whether there are differences in the incidence of AVDE according to the catheters used.Six hundred thirty-six consecutive patients undergoing primary PCI were included in the study between January 2010 and December 2012. Patients were divided into two groups: the PCI only group (465 patients) and the PCI plus manual thrombectomy group (171 patients).Thrombus aspiration was associated with higher AVDE (13.55% vs. 26.9%, p = 0.0001), lower thrombolysis in myocardial infarction frame rate (2.49 ±0.86 vs. 2.79 ±0.57, p = 0.0001), lower myocardial blush grade (2.31 ±0.87 vs. 2.47 ±0.7, p = 0.016), lower ejection fraction (EF) (49.9 ±8.5 vs. 46.1 ±9.6, p = 0.0001) and higher maximal troponin release (15.7 ±16 vs. 9.4 ±11, p = 0.0001). No difference was observed in terms of mortality between the groups in follow-up (5.2% vs. 9.03%, p = 0.12). Angiographically visible distal embolisation was observed more frequently with Invatec catheters (p = 0.0001).Angiographically visible distal embolisation during primary PCI occurs in a significant number of patients treated with manual thrombectomy. The results indicated that the incidence of AVDE may be different depending on the thrombectomy catheters used.

10.5114/amsad.2016.64443

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Citations (1)

e-Journal of Cardiovascular Medicine (2017)

Mehmet Ertürk Fatma Turhan Caglar İsmail Bıyık Nilgün Işıksaçan Serkan Yazan

Introduction:Recently, many hematologic markers have identified as prognostic and diagnostic indicators in different acute coronary syndrome (ACS) patients.In particular, neutrophil / lymphocyte ratio (NLR) and platelet / lymphocyte ratio (PLR) are recognized as markers in the diagnosis and prognosis of ACS.In this study, our aim was to investigate the correlation between the diagnostic yield of PLR and NLR values and other markers such as troponin in all ACS patients.Material and methods: 319 patients admitted to our hospital with ACS and 283 control patients were included in the study.Leukocyte, neutrophil, platelet, lymphocyte counts, PLR, NLR and high sensitive troponin I (HsTnI) measurements were taken.Results: Leukocyte, neutrophil and platelet counts were significantly higher in the ACS group than the controls (p <0.001).Lymphocyte count was significantly lower in the ACS group than the controls (p <0.001).NLR and PLR were found to be significantly higher in the ACS group than the controls (4.0 ± 3.3 vs 2.1 ± 1.4 and 126.3 ± 68.9 vs 106.9 ± 49.4, p <0.001, respectively).NLR was showed significant correlation with HsTnI, PLR, angina time, presence of ST elevation and T wave negativity (p <0.05), and PLR revealed significant correlation with NLR, HsTnI, ST elevation and T wave negativity (p <0.05). Conclusion:Hematologic markers were found to be significantly higher in the ACS group than the controls.The difference also continued in subgroup analyzes.NLR and PLR correlated with many other ACS indicators.

10.15511/ejcm.17.00466

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Citations (0)

Aortic and Mitral Valvular Involvement and Serious Coronary Artery Disease Associated with Sneddon Syndrome

The American Journal of Cardiology (2018)

İsmail Bıyık Erol Bahtiyar Şirin Küçük

Etiology

Coronary arteries

valvular heart disease

Stroke

10.1016/j.amjcard.2018.03.101

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Increased risk of cardiovascular disease may be starting in childhood: 25 OH vitamin D levels in Turkish Children

e-Journal of Cardiovascular Medicine (2018)

Nilgün Işıksaçan İsmail Bıyık Pınar Kasapoğlu

Background:Vitamin D deficiency has become global health problem and it is associated with metabolic syndrome, type 2 diabetes mellitus, cancer, cardiovascular diseases and increased mortality.The aim of this study is to shed light on the 25 OH vitamin D status in different age groups of Turkish children.Materials and Method: 1597 children (753 boys (47.2 %) and 844 girls (52.8 %)) admitted to Pediatry Outpatient Clinic were enrolled in this study.25 OH vitamin D analysis was performed from venous blood samples using Cobas e411 auto-analyzer (Roche Diagnostics, USA). Results:The children were between 0 and 18 years old, mean of age was 6.90 ± 5.1 years (median: 6 year).25 OH vitamin D levels were between 3 and 70 ng / mL, mean value was 32.4 ± 16.9 ng / mL (median: 29.1 ng / mL).Age and vitamin D levels were inversely correlated and a statistically significant difference was observed between these two parameters (r=-0.450;p=0.0001).Very low vitamin D levels (<10 ng / mL) differed significantly according to gender.It was found significantly higher in girls (p<0.05). Conclusion:Vitamin D deficiency is not rare in Turkish children, especially in adolescent period and girls.Vitamin D levels decrease with increasing age throughout childhood.Because of its association with metabolic syndrome, type 2 diabetes mellitus, hypertension and cardiovascular diseases, vitamin D deficiency in childhood may play a role in the development of these diseases in future.Large scale cohort studies are needed to reveal whether there is such an association.

10.15511/ejcm.18.00101

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Citations (1)

Effect of age and gender differences on high-sensitive troponin T measurement in the diagnosis of acute myocardial infarction

Journal of Laboratory Medicine (2019)

Nilgün Işıksaçan İsmail Bıyık Selçuk Opan Fatma Nihan Turhan Çağlar Mehmet Ertürk

Abstract Background Cardiac troponins are the recommended markers for the detection of acute myocardial infarction (AMI). There is a controversy regarding their decision limits. In this study, our objective was to reveal the cut-off values of high-sensitive troponin T (hsTnT) for AMI diagnosis in our population and to examine the effect of age and gender on hsTnT cut-off values. Methods Patients who presented to the emergency department (ED) with chest pain were selected, and only those patients admitted during the first 3–6 h of symptom onset were included in the study. Results A total of 484 men and 182 women were included. A total of 355 (279 men/76 women) patients were diagnosed with AMI. The cut-off values of hsTnT were found to be 17 ng/L and 16 ng/L, for males and females, respectively. The cut-off values of hsTnT were detected to be significantly higher in men over 40 years of age (24 ng/L) than in men less than 40 years of age (10 ng/L). Conclusions The cut-off value for the hsTnT test for AMI was slightly lower in females than in males. The cut-off levels of hsTnT for the diagnosis of AMI were found to be significantly higher in men over 40 years of age than in men less than 40 years of age.

Troponin T

10.1515/labmed-2018-0326

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Citations (6)

OP-063 T-786-c Endothelial Nitric Oxide Synthase Gene Polymorphism and Coronary Collateral Circulation

The American Journal of Cardiology (2015)

Seçkin Satılmış Emrah Bozbeyoğlu İsmail Bıyık Emre Aruğaslan Burak Tangürek

Gene polymorphism

Collateral circulation

10.1016/j.amjcard.2015.01.109

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Citations (0)