M.R. Dimitrijević

Univerzitetski Klinički Centar Srbije

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A.M. Sherwood

Baylor College of Medicine

P.C. Sharkey

University of Divinity

William McKay

University of Colorado Anschutz Medical Campus

Karen Minassian

Medical University of Vienna

J. Faganel

Baylor College of Medicine

Frank Rattay

TU Wien

Winfried Mayr

Medical University of Vienna

Meta M. Dimitrijevic

Baylor College of Medicine

J.A. Halter

Baylor College of Medicine

André Olivier

Universidade do Vale do Rio dos Sinos

Cooperative Institutions

Neurological Surgery

106

Baylor College of Medicine

University College London

Inserm

McGill University

National Hospital for Neurology and Neurosurgery

The University of Tokyo

Harvard University

University of Belgrade

Montreal Neurological Institute and Hospital

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Development of neurophysiological aspects of the spinal cord during the past ten years

Spinal Cord (1992)

M.R. Dimitrijević

Neurophysiology

10.1038/sc.1992.32

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Citations (7)

[Role of epilepsy in the pathogenesis of ovarian dysfunction].

PubMed (1975)

Trampuz M.R. Dimitrijević J Kryzanovski

Pathogenesis

Source

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Citations (7)

Reflex effects of vibration in patients with spinal cord lesions

Neurology (1977)

M.R. Dimitrijević William A. Spencer Jože V. Trontelj Meta M. Dimitrijevic

The vibration reflex was studied in 49 patients with traumatic spinal cord lesions. It was elicited in all patients, even after presumably complete division of the cord. The vibration reflex consisted of a short-latency, brief outburst of phasic activity of motor units, followed by rapidly decreasing phasic component and a later slowly declining tonic component. When periods of vibration were repeated at short intervals of 2 to 10 seconds, the responses showed an approximately exponential decline, although the beginning of each subsequent response was always larger than the end of the preceding response. A large part of this decline can be characterized as a habituation of the vibration reflex. In comparison with the vibration reflex in normal subjects, the phasic component was increased and the tonic one reduced. The tonic component was especially susceptible to potentiation and dishabituation by voluntary effort to contract the vibrated muscle, even in some patients with no other evidence that the lesion was incomplete. We suggest that the tonic component of the human vibration reflex depends, at least in part, on segmental interneurons and their descending spinal pathways, while the phasic component depends mainly on the excitability level of spinal motoneurons.

Tonic (physiology)

Stretch reflex

10.1212/wnl.27.11.1078

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Citations (40)

5. Rehabilitation - The view of the neurophysiologist

International Journal of Rehabilitation Research (1979)

M.R. Dimitrijević L S Illis E.M. Sedgwick

Dimitrijevic, Milan M.D.(1); Illis, L. S. M.D., B.Sc., F.R.C.P.(2); Sedgwick, E. M. M.D., B.Sc.(3) Author Information

10.1097/00004356-197902031-00005

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Citations (0)

Reflex path length and clonus frequency.

Journal of Neurology Neurosurgery & Psychiatry (1985)

Paul Nathan M.R. Dimitrijević A.M. Sherwood

Clonus

10.1136/jnnp.48.7.725

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Citations (5)

Early and late motor evoked potentials reflect preset agonist–antagonist organization in lower limb muscles

Muscle & Nerve (1995)

Ina M. Tarkka William McKay A.M. Sherwood M.R. Dimitrijević

Abstract A single transcranial magnetic stimulus can evoke two involuntary muscle responses in lower limb muscles of healthy humans. The purpose of the present study was to find out if these responses, when evoked during the processing period of a simple or choice reaction time task, such as ankle dorsiflexion, have specific characteristics related to the task. During the auditory reaction time, a transcranial magnetic stimulus was delivered to observe changes in the excitability of the central nervous system. A dual‐cone coil was used, which effectively stimulated the fairly deep‐lying lower limb motor cortex. Stimuli were delivered in a random order with 20–300‐ms delays from the auditory gosignal. Motor evoked potentials (MEP) in right and left anterior tibial and soleus muscles were analyzed while early MEPs were observed invariably in both muscles; late MEPs occurred consistently only in soleus muscles. Both early and late MEP amplitudes were larger in simple reaction time trials than in choice reaction time trials. The late MEP appeared earlier in the simple reaction time task than in the choice reaction time task, reflecting faster central processing of simple reaction time tasks. The amplitude of the soleus late MEP in the simple reaction time task followed closely the amplitude of anterior tibial early MEP, suggesting a preset agonist–antagonist organization. This relationship was not present in the choice reaction time task.© 1995 John Wiley &Sons, Inc.

Stimulus (psychology)

Evoked potential

Choice reaction time

10.1002/mus.880180303

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Citations (10)

Subject Index Vol 46, 1983

Stereotactic and Functional Neurosurgery (1983)

Michael P. Remler William H. Marcussen C. Reyes‐Vázquez Nachum Dafny M.R. Dimitrijević

10.1159/000101282

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Co-activation of ipsi- and contralateral muscle groups during contraction of ankle dorsiflexors

Journal of the Neurological Sciences (1992)

M.R. Dimitrijević William McKay I. Sarjanovic A.M. Sherwood L. Svirtlit

10.1016/0022-510x(92)90092-y

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Citations (64)

Central modulation of compound motor action potential responses to epidural spinal cord stimulation

A.M. Sherwood D.C. Lee M.R. Dimitrijević P.Y. Ktonas

Stimulation at frequencies from 1 to 50 Hz was applied over the dorsal surface of the lumbar enlargement in spinal cord injury subjects. Low-frequency responses appeared that were similar to compound motor action potentials (CMAPs) evoked by peripheral nerve stimulation. Close examination of the EMG response to higher frequencies (30-50 Hz) revealed that the EMG was comprised of a series of CMAPs of varying shape and amplitude. Under appropriate conditions, a constant train of stimuli evoked cyclic bursting activity. Examination of the characteristics of that activity revealed that intra-burst and burst phases were comprised of CMAPs of very different morphologies with markedly different latencies. These findings suggest that stimulation-induced activity was processed through different pathways, depending on the system state.

Bursting

10.1109/iembs.1997.757037

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Restorative Neurology of Motor Control after Spinal Cord Injury

Oxford University Press eBooks (2011)

Keith E. Tansey Meta M. Dimitrijevic Winfried Mayr M. Bijak M.R. Dimitrijević

Abstract This chapter discusses how established procedures using physiotherapy, neuromuscular and peripheral nerve stimulation, and spinal cord stimulation can be used as restorative procedures. It describes how the same restorative neurological procedures can be used to assess motor control. It also presents the intrathecal application of Baclofen and intramuscular injection of botulinum toxin (Botox) as examples of interventions that do not take advantage of residual motor control but rather suppress it. Briefly, it describes how clinical restorative neurological treatment can best be practiced in medical centers where multidiscipline programs exist.

10.1093/acprof:oso/9780199746507.003.0003

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Citations (2)