Divya Singh

UCLouvain Saint-Louis Brussels

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Suchi Jain

Dr. B. R. Ambedkar National Institute of Technology Jalandhar

Amod Kumar Sachan

King George's Medical University

Ajay Kumar Verma

King George's Medical University

Shireen Barua

Chhatrapati Shahu Ji Maharaj University

Rajendra Nath

King George's Medical University

Rakesh Dixit

King George's Medical University

Surya Kant

King George's Medical University

Garima Adhaulia

Therapeutics Clinical Research

Preet Lakhani

Johnson & Johnson (India)

Dan Hoang

University of California, Irvine

Cooperative Institutions

King George's Medical University

Chhatrapati Shahu Ji Maharaj University

Institute of Medical Sciences

All India Institute of Medical Sciences

Dr. Ram Manohar Lohia Institute of Medical Sciences

Chandigarh University

Banaras Hindu University

Amity University

Diabetes Foundation

PSG INSTITUTE OF TECHNOLOGY AND APPLIED RESEARCH

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Review of Ayurvedic medicinal plants recommended for the treatment and management of diabetes mellitus

International Journal of Home Science (2024)

Divya Singh AC Kar

Diabetes mellitus (Madhumeha) is a well-known disease of endocrine disorder. People of ancient India well knew about this disease. In Ayurveda Diabetes mellitus is classified under a category of 'Prameha' (Urine disorders) and termed as 'Madhumeha'. Madhumeha is a condition of passing excessive turbid urine which is sweet in nature. Ayurvedic texts have mentioned many medicinal plants for the treatment and management of diabetes mellitus such as Guduchi, Amla, Jamun, ash-gourd, Pippali, Castor, Devdaru, Onion, Fenugreek, Makoi, etc. Various parts of these plants such as leaves, stems, roots, fruits, and seeds are used for curative purposes. The names of these medicinal plants were collected from 'Dravyaguna Vijnana' of Sastry, J.L.N (2010), and the related supporting literature was collected from various online databases viz. Google Scholar, PubMed, etc.

Ayurvedic medicine

Diabetes management

10.22271/23957476.2024.v10.i2a.1599

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Superinfection of Mucormycosis in Post-COVID-19 Patients with Diabetes at Tertiary Care Hospital in Eastern Uttar Pradesh

UP Journal of Ophthalmology (2024)

Reena Sachan Abhishek Singh Aditi Garg Divya Singh

Introduction and Objectives: To determine the prevalence of mucormycosis in post COVID-19 patients. To understand the risk factor mainly diabetes and its association with post COVID-19 mucormycosis.Method and Material: This a retrospective observational study of post-COVID-19 patients associated with mucormycosis which were managed in a tertiary care centre of Eastern UP from March 2021 to February 2022. The tissue sample for study was taken from surgical and medicine wards of the centre and the study was conducted in Microbiology Department. The procedures followed to process the sample were: 10% KOH mount after teasing the tissue. Culture on Sabouraud dextrose agar (SDA) with chloremphenicol and the fungal growth was stained with lactose phenol cotton blue (LPCB) for microscopyConclusion: There has been a surge in cases of mucormycosis in COVID-19 era. Uncontrolled diabetes and other immunocompromised states predispose to its development mainly in adult patients where diabetes is the most important predisposing factor. Although, early presentation and intervention play a very important part. Tight glycemic control, Amphotericin B and surgical debridement can lead to favourable outcomes.

Uttar pradesh

Superinfection

Tertiary care

10.56692/upjo.2024120104

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Elsevier eBooks (2023)

Subramaniam Abbirooban K. Abilash K. Abilash Kriti Ahuja Mohammed Hasan Ali Al‐Abyadh

10.1016/b978-0-443-19096-4.01002-6

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A Review on Nanosuspensionspromising Drug Delivery Strategy.

Journal of Current Pharma Research (2012)

Toshi Chaurasia .Divya Singh Nimisha Dipti Srivastava

10.33786/jcpr.2012.v03i01.010

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Drug repositioning: Achievements, advancements and barriers

IP International Journal of Comprehensive and Advanced Pharmacology (2019)

Divya Singh Suchi Jain Garima Adhaulia Shireen Barua Amit Sachan

Drug repositioning: Achievements, advancements and barriers - IJCAAP- Print ISSN No: - 2581-5555 Online ISSN No:- 2456-9542 Article DOI No:- 10.18231/j.ijcaap.2019.003, IP International Journal of Comprehensive and Advanced Pharmacology-IP Int J Compr Adv Pharmacol

Drug repositioning

10.18231/j.ijcaap.2019.003

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Repeated Pneumoniain Children with Congenital Heart Disease in Tertiary care Hospital at Jharkhand

Journal of Cardiovascular Disease Research (2023)

Parthakumar Chaudhuri Divya Singh Bhuwankumar Singh

Background: Functions of the respiratory and cardiovascular systems have a close relationship.Congenital heart disease (CHD) affects the respiratory system and result in respiratory morbidities.Repeated pneumonia is one such morbidity.Aim: To assess the incidence of CHD in patients presenting with repeated pneumonia and the incidence of different types of CHD in patients detected with congenital heart defects.Materials and Methods: A total of 100 patients with repeated pneumonia were studied (N = 100), which included 60 males and 40 females.All the patients were subjected to clinical examination and were made to undergo chest X-ray, electrocardiography, and 2D echocardiography with colour Doppler to detect CHD.Results: Of the 100 patients, 43 patients (23 [53.4%] males and 20 [46.5%] females) with repeated pneumonia were found to have CHD.Conclusions: The results reveal that CHD is a major cause for recurrent LRTI.Considering this, it would be prudent to screen all children presenting with repeated pneumonia for CHD.

Tertiary care

10.48047/jcdr.2019.2.20

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Analgesic Activity-Based Formulation, Optimization, and Evaluation of <i>Curcuma caesia</i> Herbal Cream

International Journal of Newgen Research in Pharmacy & Healthcare (2024)

Merajuddin Khan Tarun Bathrey Mohsina Bano Divya Singh Mohit K Baghel

Herbal analgesic creams, which harness the pain-relieving properties of plants, provide a novel, potentially risk-free approach to pain relief. To make this formulation, we took a number of tried-and-true herbal analgesic cream recipes and optimized their active ingredient ratios. Important factors in their choice of turmeric were its analgesic and anti-inflammatory properties. After making the herbal extracts, the cream was made using a double boiling method. The final products' pH, spreadability, stability, irritancy, and physical properties were then thoroughly tested. Since each composition was uniform in color (mustard), texture (semi-solid), and aroma, it was clear that they were all mass-produced. Because they were all within the safe pH range—which is mildly acidic to slightly alkaline—none of the formulations were irritating to the skin. Because they did not cause any irritation when tested topically, the creams were deemed safe for topical use. The spreadability tests revealed that it was rather easy to implement, which bodes well for its prospective usefulness. Furthermore, all formulations showed no signs of phase separation, indicating chemical homogeneity. This work opens new possibilities for research and development in natural medicine by providing encouraging evidence that herbal analgesic creams can be a safe and effective alternative to traditional pain and inflammation treatments.

10.61554/ijnrph.v2i2.2024.115

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Polypharmacy: Remedy Leads to Illness

Journal of Biomedical and Pharmaceutical Research (2024)

Archana Mishra Surbhi Jangir Divya Singh

Background: People often engage in polypharmacy, which is outlined as taking more drugs than is clinically required or using many prescriptions at one time. Objective: The goal of this research was to provide a descriptive analysis of polypharmacy and to perform the clinical assessment of the patients as well as assess their behavioural changes. Methods: A cross-sectional study was performed in tertiary care hospital over five months. A total 100 patients are included. The study population include cardiovascular and diabetic patients. Medicine card containing more than 5 medicines are included. Data collection was done by personal communication with the patients which prevents the manipulation of the information. The collected data are determined through graphical methods. Results: Polypharmacy patients were experiencing excessive behavioural changes such as anxiety and frustration. Statins and Biguanides group of medicine are prescribed more. The blood pressure and heart rate of the patients were also changing continuously due to medicines and hospital restrictions. It was found that diet and oxygen saturation level is not affected by Polypharmacy as these are continuously monitored by the hospital staffs. Conclusion: Polypharmacy frequently leads to an increased risk of medical related issues. Throughout this study, it was found that patients have major effect on their blood pressure and heart rate simultaneously which could be due to number of medicines prescribed or the hospital environment and restriction. Changes in the patient behaviour is also one of the major concerns which needs to be focused sincerely. Keywords: Polypharmacy, Blood Pressure, Heart Rate, Behaviour, Cardiovascular

10.32553/jbpr.v13i4.1096

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Study of prescribing pattern of drugs used in the treatment of bronchial asthma at tertiary care hospital of northern India

International Journal of Basic & Clinical Pharmacology (2020)

Garima Adhaulia Divya Singh Suryakant Ajay Kumar Verma Arpita Singh

Background: Asthma is a chronic inflammatory disease requiring long term treatment. For an effective control of asthma symptoms background knowledge of the prescribing pattern of anti-asthmatic drugs is a must.Methods: A prospective, observational study was conducted in the Department of Respiratory Medicine OPD, King George's Medical University, Lucknow. 114 patients of asthma were recruited for the study. A case report form was filled from patient’s prescription containing the demographic details of the patients, presenting complaints, investigations and drugs prescribed along with their dose, duration, frequency, route of administration.Results: 114 patients’ prescriptions were assessed which showed average number of drugs per prescription - 3.22. 42.8% and 50% of the drugs were prescribed in accordance with World Health Organization model list of essential medicines and National list of essential medicines. Short acting β2 agonist (salbutamol), 61.4% was the most commonly and frequently prescribed single anti asthmatic drug. Combination of inhaled corticosteroid and long acting β2 agonist, 86.8% was the most commonly prescribed fixed dose combination anti asthmatic drug. Inhalational route (75%) was the most preferred one over oral route (25%).Conclusions: Asthma being a chronic disease requires prolonged treatment which imposes economic burden on the patients. Judicious prescription of drugs not only improves the patient clinically but also removes the unnecessary burden. Data obtained from these studies can be used as a guide to make future decisions regarding standard prescription.

10.18203/2319-2003.ijbcp20200184

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A COMPARATIVE STUDY OF DRUG INTERACTION AND SIDE-EFFECT OF DRUG FOR TREATMENT OF DIABETES MELLITUS: A REVIEW

International Research Journal of Pharmacy (2018)

Monika Yadav Nikita Saraswat Pranay Wal Awani Kumar Divya Singh

The objective of this review paper is to examine diabetes and via the modifying drugs treatment how to improve the patient condition and related risks.The review mentions the different types of comparative drugs which are useful for diagnosis or prevention of diabetes.Treatment modification can play a major role in the decreasing the diabetic patients.In India, a concerning 1-5% by population affected by diabetes or related difficulty.So there is required to use medications to cure the disease.If a patient suffers from diabetes used anti-diabetic drugs.These drugs are recommended for lowering the blood glucose levels.Metformin, Acarbose, thiazolidinedione etc.Most of the drugs are administered via orally so that called oral hypoglycemic or oral antihyperglycemic agents.Present days for treatment of diabetes available, different classes of anti-diabetic drugs and their choice depending on the patient diabetic type or the condition, age as well as other factors.Type 1 diabetes mainly caused by deficiency of insulin secretion the body.Researcher around the world focused on oral hypoglycemic agents and presents various types of comparative study to control the diabetes mellitus.The present review summarizes the comparative study of anti-diabetic drugs for the treatment of diabetes.This review article has shown a comparative study of drugs which are metformin more popular drug treatment of diabetes and they have the less side effect or higher efficacy, mention in the recently published articles.

10.7897/2230-8407.09682

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