Objective To examine the influence of early rehabilitation therapy on hemiplegic motor function and daily living ability of patients with acute stroke.Methods Ninety-six patients with acute stroke were randomly assigned into rehabilitation group(n = 50)and control group(n= 46).All participants were treated by conventional medical treatment.The rehabilitation group also received early rehabilitation therapy.Fugl-Meyer scores were used to estimate mote function after 48 hours of strock while ADL scores were used to evaluate daily living ability after 28 days of rehabilitation therapy.Results The scores of Fugl-Meyer and ADL in the rehabilitation group are significantly higher than that in the control group(P0.01).Conclusion The early rehabilitation therapy remarkably improves the hemiplegic motor function and living ability in patients with acute stroke.
[Objective] To investigate the usage of aspirin after the first stroke in patients with recurrent stroke,to explore and analyze some irregular usages in clinical application.[Methods] Selected 118 in 479 cases of recurrent stroke patients to be in hospital from September 2003 to March 2008,investigated their usage of aspirin after the first stroke,and analyzed some irregular usage of aspirin.[Results] All the 118 patients took aspirin 75-150mg daily in hospital.However,92 patients(77.97%) took aspirin irregularly after leaving hospital.Among them,63 patients(53.39%) insisted on aspirin therapy,but 37 cases(58.73%) took low dosage aspirin and 55 cases(46.61%) took aspirin interruptedly.The main cause of irregular usage of aspirin were that patients worried about the unwanted side effects,felt troublesome of taking medicine daily,believed in it was a noneffective therapy by them or their families,were not been informed a long term therapy by the doctor,didn' t insist on visiting neurologist regularly in outpatient departments and never received any specialist' s advices,ignored to been asked about dose usages by the doctor in outpatient departments,canceled the drug therapy due to unwanted side effects such as stomach discomfort and rash.[Conclusion] A considerably amount of recurrent patients after they first stroke take aspirin with low dosage and not insisted on the therapy.So it is quite important to reinforce the education for patients on stroke as well as health care to enhance the compliance on aspirin therapy.
Objective:To analyse clinical curative effect and the safety of shenXiong injection in treatment of acute cerebral infarction(ACI) on the basis of strict quality evaluation.Methods:By overall collecting clinical trial of shenXiong injection in treatment of ACI,using meta analysis of fixed effect model made an estimation of homogeneity test and overall effect for 19 researches,found and analyzed publication difference with funnel figure.Results:Homogeneity test: χ2 = 6.413,D/F was 18,P0.05;Estimation of merging effect value: OR merging=3.476,OR merging 95% confidence interval was: 2.680~4.510;OR merging test: χ2=87.982,P0.01.Adverse effect was less,funnel figure showed there existed publication bias.Conclusion:ShenXiong injection has confirmative curative effect in treatment of ACI.It is safe and has less adverse effect.However,there still need some strict and multicentric randomized double-mind control tests to be carried out,in order to provide more effective and convinced evidence.
Objective To study the risk factors for vascular cognitive impairment (VCI) after lacunar infarct (LACI). Methods A total of 138 patients with LACI were evaluated by Montreal Cognitive Assessment (MoCA), and divided into normal cognitive function group (normal, N = 55), mild cognitive impairment (MCI) group (mild, N = 73) and severe cognitive impairment group (severe, N = 10). Univariate and backward multivariate Logistic regression analysis were used to screen the risk factors for VCI after LACI. Results Logistic regression analysis showed that infarct in critical site ( OR = 1.179, 95% CI: 0.870-2.472; P = 0.012) and white matter hyperintensity (WMH) Grade 3-4 ( OR = 2.005, 95% CI: 0.910-4.502; P = 0.024) were independent risk factors for VCI in patients with LACI. Conclusions VCI in patients with LACI is related to multiple factors, in which infarct in critical site and WMH Grade 3-4 are independent risk factors. DOI: 10.3969/j.issn.1672-6731.2016.11.010