Xiaoling Yang

Wenzhou Medical University

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Haixiang Gao

China Agricultural University

Wenfeng Zhou

China Agricultural University

Sanbing Zhang

China Agricultural University

Runhua Lu

China Agricultural University

Miyi Yang

Chinese Academy of Medical Sciences & Peking Union Medical College

Xiangming Quan

University of Electronic Science and Technology of China

Ying Bai

Hebei University of Engineering

Yaping Xu

Tongji University

Jie Shi

Zhangzhou Normal University

Fei Han

Chinese Academy of Medical Sciences & Peking Union Medical College

Cooperative Institutions

Zhejiang University

China Agricultural University

Chinese Academy of Sciences

Wenzhou Medical University

Ningbo University

Affiliated Eye Hospital of Wenzhou Medical College

Ministry of Agriculture and Rural Affairs

Shanghai Jiao Tong University

Xi'an Jiaotong University

University of Pittsburgh

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Diffusion tensor imaging of white matter in patients with prediabetes by trace‐based spatial statistics

Journal of Magnetic Resonance Imaging (2018)

Minjie Liang Xiangyi Cai Yi Tang Xiaoling Yang Fang Jin

Background Prediabetes is an intermediate state in which blood glucose is higher than normal but does not meet the diagnostic criteria for diabetes. Diffusion tensor imaging (DTI) is an MRI method that can sensitively detect microscopic lesions in the white matter of the brain, but most previous DTI studies only focused on patients with diabetes, and little is known about prediabetes. Purpose To investigate the changes in the microstructure of brain white matter in prediabetes patients using DTI and trace‐based spatial statistics (TBSS). Study Type Prospective. Population Sixty subjects (30 patients with prediabetes and 30 healthy volunteers) were enrolled. Field Strength/Sequence 3.0T/DTI‐MRI sequence with single‐shot echo‐planar imaging sequence (SE‐EPI). Assessment DTI data were collected and analyzed using the TBSS method in the FMRIB software library. Statistical Tests DTI using a two‐sample t ‐test. Pearson correlation analysis was performed on DTI values and neuropsychology scale results (mini‐mental state examination [MMSE], Montreal cognitive assessment [MoCA], self‐rating anxiety scale [SAS], and self‐rating depression scale [SDS]) Results Compared with the control group, the fractional anisotropy (FA) values in the right part of the corpus callosum body (bCC) ( P = 0.035), the right superior longitudinal fasciculus (SLF.R) ( P = 0.047), and the left superior longitudinal fasciculus (SLF.L) in the prediabetic group were reduced ( P = 0.040). Data Conclusion DTI as a noninvasive technique can assess early changes in the white matter microarchitecture of patients with prediabetes. Level of Evidence : 2 Technical Efficacy : Stage 2 J. Magn. Reson. Imaging 2019;49:1105–1112.

Prediabetes

Superior longitudinal fasciculus

10.1002/jmri.26290

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Citations (17)

Design of a Pressure-Swing Distillation Process for the Separation of n-Hexane and Ethyl Acetate Using Simulated Annealing

Computer-aided chemical engineering/Computer aided chemical engineering (2018)

Xiaoling Yang Jeffrey D. Ward

Hexane

10.1016/b978-0-444-64241-7.50015-x

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Citations (3)

Identify Changes of Brain Regional Homogeneity in Bipolar Disorder and Unipolar Depression Using Resting-State fMRI

PLoS ONE (2013)

Minjie Liang Quan Zhou Kan‐Rong Yang Xiaoling Yang Fang Jin

Background To identify changes in brain activation patterns in bipolar disorder (BD) and unipolar depression (UD) patients. Methodology/Principal Findings Resting-state fMRI scans of 16 healthy controls, 17 BD and 16 UD patients were obtained. T-test of normalized regional homogeneity (ReHo) was performed in a voxel-by-voxel manner. A combined threshold of á = 0.05, minimum cluster volume of V = 10503 mm3 (389 voxels) were used to determine ReHo differences between groups. In UD group, fMRI revealed ReHo increases in the left middle occipital lobe, right inferior parietal lobule, right precuneus and left convolution; and ReHo decreases in the left parahippocampalgyrus, right precentralgyrus, left postcentralgyrus, left precentralgyrus and left cingulated. In BD group, ReHo increases in the right insular cortex, left middle frontal gyrus, left precuneus, left occipital lobe, left parietal, left superior frontal gyrus and left thalamus; and ReHo decreases in the right anterior lobe of cerebellum, pons, right precentralgyrus, left postcentralgyrus, left inferior frontal gyrus, and right cingulate. There were some overlaps in ReHo profiles between UD and BD groups, but a marked difference was seen in the thalamus of BD. Conclusions/Significance The resting-state fMRI and ReHo mapping are a promising tool to assist the detection of functional deficits and distinguish clinical and pathophysiological signs of BD and UD.

Occipital lobe

Parietal lobe

Limbic lobe

10.1371/journal.pone.0079999

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Citations (132)

NOVEL THREE TYPES OF NEOVASCULARIZATION ELSEWHERE DETERMINE THE DIFFERENTIAL CLINICAL FEATURES OF PROLIFERATIVE DIABETIC RETINOPATHY

Retina (2020)

Jiandong Pan Feng Chen Chen Ding Xiaoling Yang Jie Wang

To explore the pathological features and clinical significance of three types of neovascularization elsewhere (NVE) in proliferative diabetic retinopathy.Neovascularization elsewhere was classified based on the origins and morphologic features using fluorescein angiography and angiographic and structural optical coherence tomography. The topographical distribution, vitreoretinal interface, and responsiveness to panretinal photocoagulation were compared among three types of NVE.One hundred and twenty-seven NVEs were classified into three types. Type 1 NVE was concentrated along or adjacent to vascular arcades; Type 2 was distributed more peripherally than were Types 1 and 3 NVE. The arch bridge-like vitreoretinal interface accounted for 79% of Type 1 NVE. The flat and flat-forward vitreoretinal interface accounted for 95% and 100% in Type 2 and Type 3 NVE, respectively. At 3 months after panretinal photocoagulation, the regression rates for Types 1, 2, and 3 NVE were 82%, 100%, and 80%, respectively. Type 2 NVE showed best regression rate after panretinal photocoagulation (both P < 0.01).Three types of NVE determine the distinctly topographical distributions, vitreoretinal interface features, and differential responsiveness to panretinal photocoagulation treatment. This new concept may have important clinical implications in assessing the treatment and prognosis of proliferative diabetic retinopathy.

Panretinal photocoagulation

10.1097/iae.0000000000003005

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Citations (4)

Ultrasound-assisted emulsification magnetic microextraction: a fast and green method for the determination of triazole fungicides in fruit juice

Analytical Methods (2014)

Yubo Li Xiaoling Yang Jiaheng Zhang Min Li Xuhao Zhao

A fast microextraction technique, termed as ultrasound-assisted emulsification magnetic microextraction, was developed for the determination of triazole fungicides (penconazole, tebuconazole and myclobutanil) in fruit juice samples by gas chromatography flame ionization detection. The distinct advantage of the proposed method is that a low toxic solvent, 1-octanol, is used as an extractant, without using a disperser. With the help of ultrasound, emulsification can be obtained. Magnetic nanoparticles are applied to retrieve the extractant, replacing centrifugation. Under optimal conditions, good linearity in the range of 5 μg L−1 to 500 μg L−1, repeatability (RSD 3.5–7.7%), low LODs (1.8–2.3 μg L−1) and good recovery (85.4–105%) were obtained. Additionally, the intermolecular binding energies were theoretically studied using density functional theory and the explicit solvent molecule model. A high correlation was found among the extraction efficiency, Kow and the calculated energies, which may guide the application of extractants and the selectivity of the target analytes in analytical methods.

Myclobutanil

Tebuconazole

Disperser

Repeatability

Triazole

10.1039/c4ay01190b

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Citations (12)

Elevated Intraocular Pressure and Citicoline Affect Functional Connectivity in the Visual Pathway

Kevin C. Chan Yolandi van der Merwe Matthew C. Murphy Leon C. Ho Xiaoling Yang

Affect

Citicoline

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A Novel Polyacrylamide-divinylbenzene Functionalized Fe3O4/Coconut Shell Adsorbent with Superior Capacity for Removal of Acridine Orange

Huan Wang Wei Zhao Youning Chen Xiaoling Yang Xiaohua Meng

Divinylbenzene

Acridine orange

Polyacrylamide

Source

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Citations (1)

TRIDENT 200TW ""Dial-A-Contrast"" Laser System Experiments, Producing Protons up to 75 MeV

OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (2011)

Kirk Flippo Sandrine Gaillard Dustin Offermann J. Ren J. A. Cobble

Trident

Dial

Source

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Dispersive micro‐solid‐phase extraction of benzoylurea insecticides in honey samples with a β‐cyclodextrin‐modified attapulgite composite as sorbent

Journal of Separation Science (2015)

Panjie Zhang Xiangqian Cui Xiaoling Yang Sanbing Zhang Wenfeng Zhou

A β‐cyclodextrin‐modified attapulgite composite was prepared and used as a dispersive micro‐solid‐phase extraction sorbent for the determination of benzoylurea insecticides in honey samples. Parameters that may influence the extraction efficiency, such as the type and volume of the eluent, the amount of the sorbent, the extraction time and the ionic strength were investigated and optimized using batch and column procedures. Under optimized conditions, good linearity was obtained for all of the tested compounds, with R 2 values of at least 0.9834. The limits of detection were determined in the range of 0.2–1.0 μg/L. The recoveries of the four benzoylurea insecticides in vitex honey and acacia honey increased from 15.2 to 81.4% and from 14.2 to 82.0%, respectively. Although the β‐cyclodextrin‐modified attapulgite composite did not show a brilliant adsorption capacity for the selected benzoylurea insecticides, it exhibited a higher adsorption capacity toward relatively hydrophobic compounds, such as chlorfluazuron and hexaflumuron (recoveries in vitex honey samples ranged from 70.0 to 81.4% with a precision of 1.0–3.7%). It seemed that the log P ow of the benzoylurea insecticides is related to their recoveries. The results confirmed the possibility of using cyclodextrin‐modified palygorskite in the determination of relatively hydrophobic trace pharmaceutical residues.

Solid phase extraction

Central composite design

10.1002/jssc.201500970

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Citations (24)

Micro- and nano-fibers for organ-on-a-chip: Construction, applications, and prospects

Materials Today Bio (2024)

Xiaoling Yang Jingyan Shi Bori Shi Jianing Li Chang Xue

Organ-on-a-Chip

3D cell culture

Organ culture

10.1016/j.mtbio.2024.101322

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Citations (0)