In recent years solid Li+ conductors with competitive ionic conductivity to those of liquid electrolytes have been reported. However, the incorporation of highly conductive solid electrolytes into the lithium-ion batteries is still very challenging mainly due to the high resistance existing at the solid–solid interfaces throughout the battery structure. Here, we demonstrated a universal interfacial modification strategy through coating a curable polymer-based glue electrolyte between the electrolyte and electrodes, aiming to address the poor solid–solid contact and thus decrease high interfacial resistance. The liquid glue exhibits both great wettability as well as chemical/electrochemical stability to most of the electrodes, and it can be easily solidified into a polymer electrolyte layer through a "post-curing" treatment. As a result, symmetric Li batteries with the glue modification exhibit much smaller impedance and enhanced stability upon plating/stripping cycles compared to the batteries without glue modification. The all-solid-state Li–S batteries with glue modification show significantly enhanced performances. The strategy of developing glue electrolytes to improve the electrode–electrolyte interface contact provides an alternative option for improving many other solid-state batteries.
In order to strengthen the tracking performance and robustness of permanent magnet synchronous motor (PMSM) system, a deadbeat predictive current control (DPCC) based on extreme learning machine (ELM) is come up. Since PMSM is susceptible to uncertainties such as external disturbances and parameter changes, the uncertainty factors are introduced in the mathematical model. The uncertainty of the system is approximated by the ELM, then the speed tracking of the permanent magnet synchronous motor is realized, and the stability is certificated by establishing the Lyapunov function. In addition, DPCC method of PMSM is proposed, which is equivalent to high-gain proportional control and improves the performance of the PMSM. Finally, the simulation experiments are carried out in nominal case and parameter mismatch case respectively, through the comparative study of system simulation, the results indicate that contrast with the traditional control method, The ELM-DPCC proposed in this paper has better speed tracking performance and robustness.
Hollow polymer nanospheres (HPNSs) have received an increased level of attention, not only for their fundamental scientific interest, but also for technological applications. Despite a great deal of research effort, most of the current HPNSs are suffering from a poor polydispersity as well as a particle size larger than 500 nm. Here, we report the synthesis of highly monodisperse hollow microporous polystyrene nanospheres (MHMPNSs) with diameters as low as 120 nm based on a facile hypercrosslinking strategy. We utilize the rapid formation of an almost unreactive crosslinked polystyrene outer skin during the initial hypercrosslinking process, to minimize the undesired inter-sphere crosslinking. Due to the intra-sphere hypercrosslinking, the resulting MHMPNSs possess a well-developed microporous shell structure. The MHMPNSs are able to be used as potential absorbents toward organic vapors, because of their unique hollow core and microporous shell characteristics.
This study investigated the role of the miR-871-5p/proliferator-activated receptor α (PGC1α) pathway in ameliorating hepatic steatosis. We examined miR-871-5p expression in liver tissues of aging mice and AML12 senescent cells co-induced by low serum and palmitic acid (PA). Bioinformatics and multiple experiments were employed to validate the expression level of the target gene PGC1α for miR-871-5p. In this study, we aimed to investigate the potential role of miR-871-5p in regulating hepatic lipid deposition associated with aging. To do so, we performed in vitro transfection of both miR-871-5p mimic and inhibitor into senescent hepatocytes. Our results showed that miR-871-5p could inhibit PGC1α expression and cause lipid deposition in the liver due to aging. miR-871-5p controls this process by regulating PGC1α/fatty acid β-oxidation. H&E staining displayed the appearance of fat vacuoles in the livers of aging mice, and fatty acid β-oxidation-related genes (acyl-coenzyme A oxidase 1 carnitine palmitoyl transferase 1α and peroxisome proliferator-activated receptor α) expression was significantly reduced. Lipogenic genes (sterol regulatory element binding protein 1C and fatty acid synthase) expression level was increased in the livers of aging mice. In AML12 cells co-induced by low serum and PA, miR-871-5p mimics decreased PGC1α expression and increased lipid droplet accumulation in senescent hepatocytes. Conversely, miR-871-5p inhibitor promoted PGC1α expression and reduced lipid deposition in senescent hepatocytes. Our findings suggest that inhibiting miR-871-5p could be crucial in ameliorating aging-associated hepatic steatosis. These findings offer valuable insights into the molecular mechanisms driving hepatic steatosis in aging.
The purpose of this paper is study soft landing strategies of the lunar craft during landing on the moon.On the basis of the fixed selenocenter coordinate system, we set up a braking coordinate system in the main reduction stage.Build the centroid-based dynamic differential equation model to describe the relation among different variables and for the target of least fuel consumption.Use the parameterize method to keep complex unknown variables approximate for the power function.Try the numerical iteration method for solving the model.When it comes to an approximate optimal goal, we finally get result that main reduction stage take 585 seconds, and angle of thrust direction show increased over time, and thrust decreases with time, and the rate of reduction increases with time gradually.
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