An‐An Liu

Fontys University of Applied Sciences

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Dai‐Wen Pang

Nankai University

Chenghao Shao

Changhai Hospital

Dongge Ma

Beijing Technology and Business University

Zhiling Zhang

Sun Yat-sen University Cancer Center

Zefeng Ren

Dalian Institute of Chemical Physics

Wei Zhao

State Key Laboratory of Medicinal Chemical Biology

Chuncheng Chen

Beijing National Laboratory for Molecular Sciences

Xing Liang

Sichuan Academy of Agricultural Sciences

Jundan Li

Beijing Technology and Business University

Dingbin Liu

Nankai University

Cooperative Institutions

Chinese Academy of Sciences

Nankai University

State Key Laboratory of Medicinal Chemical Biology

Wuhan University

Sun Yat-sen University

University of Chinese Academy of Sciences

Chinese Academy of Medical Sciences & Peking Union Medical College

Second Military Medical University

Peking University

Sichuan University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Ferrimagnetism in stable non-metal covalent organic framework

arXiv (Cornell University) (2022)

Dongge Ma Yuhang Qian Mingyang Ji Jiani Li Jundan Li

We synthesized a pure organic non-metal crystalline covalent organic framework TAPA-BTD-COF by bottom-up Schiff base chemical reaction. And this imine-based COF is stable in aerobic condition and room-temperature. We discovered that this TAPA-BTD-COF exhibited strong magneticity in 300 K generating magnetic hysteresis loop in M-H characterization and giant chimol up to 0.028. And we further conducted zero-field cooling and field-cooling measurement of M-T curves. The as-synthesized materials showed a large chi/mol up to 0.028 in 300 K and increasing to 0.037 in 4.0 K with 200 Oe measurement field. The TAPA-BTD-COF 1/chimol~T curve supported its ferrimagnetism, with an intrinsic delta temperature as -33.03 K by extrapolating the 1/chimol~T curve. From the continuously increasing slope of 1/chimol~T, we consider that this TAPA-BTD-COF belongs to ferrimagnetic other than antiferromagnetic materials. And the large chimol value 0.028 at 300 K and 0.037 at 4.0 K also supported this, since common antiferromagnetic materials possess chimol in the range of 10-5 to 10-3 as weak magnetics other than strong magnetic materials such as ferrimagnetics and ferromagnetics. Since this material is purely non-metal organic polymer, the possibility of d-block and f-block metal with unpaired-electron induced magnetism can be excluded. Besides, since the COF does not involve free-radical monomer in the processes of synthesis, we can also exclude the origin of free-radical induced magnetism. According to recent emerging flat-band strong correlated exotic electron property, this unconventional phenomenon may relate to n-type doping on the flat-band locating in the CBM, thus generating highly-localized electron with infinite effective mass and exhibiting strong correlation, which accounts for this non-trivial strong and stable ferrimagneticity at room-temperature and aerobic atmospheric conditions.

Ferrimagnetism

Imine

Magnetism

Unpaired electron

10.48550/arxiv.2205.07541

Cite

Citations (1)

MnCaCs-Biomineralized Oncolytic Virus for Bimodal Imaging-Guided and Synergistically Enhanced Anticancer Therapy

Nano Letters (2019)

Lili Huang Xue Li Jinfeng Zhang Qian Zhao Ming Jing Zhang

Oncolytic adenovirus (OA) is an ideal candidate for clinical anticancer treatment, because it can specifically replicate in tumor cells with high titer. However, its systemic administration is still hindered, because of severely compromised antitumor efficacy. Herein, an engineered OA was innovatively developed by enwrapping OA with calcium and manganese carbonates (MnCaCs) biomineral shell, which could protect the virus from removal of the host immune system and prolong its in vivo circulation. Upon accumulating in tumor sites, MnCaCs readily dissolved under the acidic microenvironment, releasing Mn2+ that could convert endogenous H2O2 into oxygen (O2) and then enhance the duplication ability of OA, thus significantly increased the antitumor efficacy. Meanwhile, Mn2+ and the increased O2 individually endowed the T1 modal magnetic resonance imaging (MRI) and photoacoustic imaging (PAI) feasibility, providing real-time monitoring information for the therapy. This versatile engineered OA demonstrated its promise for visible and efficient oncolytic virotherapy by systemic administration.

Systemic administration

Virotherapy

Oncolytic adenovirus

10.1021/acs.nanolett.9b03193

Cite

Citations (51)

Surgery management for sporadic small (≤2 cm), non-functioning pancreatic neuroendocrine tumors: A consensus statement by the Chinese Study Group for Neuroendocrine Tumors (CSNET)

International Journal of Oncology (2016)

Guang Yang Meng Ji Jie Chen Rufu Chen Ye Chen

The incidence of small (≤2 cm), non-functioning pancreatic neuroendocrine tumors (NF-pNETs) increased in the last decades. Before making appropriate strategy for patients with NF-pNETs ≤2 cm, pathological confirmation is vital. Incidentally diagnosed, sporadic small NF-pNETs may bring aggressive behavior and poor prognosis, such as extrapancreatic extension, lymph nodal metastasis, distant metastasis and recurrence, even causing disease-related death. Understanding and formulating an appropriate strategy for the patients with sporadic small, non-functioning pancreatic neuroendocrine tumors have been controversial for some time. Although several studies have reported that patients with NF-pNETs ≤2 cm had less rate of malignant behavior compared with larger ones (>2 cm); and the surgery approach may leading to surgery-related pancreatic complications; but there is still a lack of level I evidence to convince surgeons to abandon all cases with sporadic small NF-pNETs. Based on an updated literature search and review, the members of the Chinese Study Group for Neuroendocrine Tumors (CSNET) from high-volume centers have reached a consensus on the issue of the management strategy for the sporadic small NF-pNETs. We recommend that, except for some selected patients with NF-pNETs <1 cm, incidentally discovered and unacceptable surgical risks, all others with NF-pNETs ≤2 cm should undergo tumor resection with lymph node dissection or at least lymph node sampling and careful postoperative surveillance.

10.3892/ijo.2016.3826

Cite

Citations (42)

Covalent Organic Frameworks: A Promising Materials Platform for Photocatalytic CO2 Reductions

Molecules (2020)

Jundan Li Dongni Zhao Jiangqun Liu An‐An Liu Dongge Ma

Covalent organic frameworks (COFs) are a kind of porous crystalline polymeric material. They are constructed by organic module units connected with strong covalent bonds extending in two or three dimensions. COFs possess the advantages of low-density, large specific surface area, high thermal stability, developed pore-structure, long-range order, good crystallinity, and the excellent tunability of the monomer units and the linking reticular chemistry. These features endowed COFs with the ability to be applied in a plethora of applications, ranging from adsorption and separation, sensing, catalysis, optoelectronics, energy storage, mass transport, etc. In this paper, we will review the recent progress of COFs materials applied in photocatalytic CO2 reduction. The state-of-the-art paragon examples and the current challenges will be discussed in detail. The future direction in this research field will be finally outlooked.

Covalent organic framework

10.3390/molecules25102425

Cite

Citations (44)

In Situ Studies on Temperature-Dependent Photocatalytic Reactions of Methanol on TiO₂(110)

The Journal of Physical Chemistry C (2019)

Ruidan Zhang Haochen Wang Xingxing Peng Ranran Feng An‐An Liu

We studied the photocatalytic reaction of methanol on the TiO2(110) surface in situ by surface sum frequency generation vibrational spectroscopy. The in situ vibrational spectra of the photo-oxidation product, formaldehyde and methyl formate, on TiO2(110) was unambiguously assigned and identified. The temperature-dependent photocatalytic reaction efficiency was observed and suggested that the thermal diffusion might be important for the photocatalytic reaction. Scanning tunneling microscopy combined with ultraviolet light was used to investigate the photocatalytic reaction efficiency on the hydroxylated TiO2(110) surface, which shows that the neighboring hydroxyl group on the bridge-bonded oxygen site dramatically inhibits the photo-oxidation of methanol because of the repulsion between hydroxyl groups. Our results provide direct vibrational spectral evidence of photo-oxidation products of methanol on TiO2(110), show the importance of thermal processes in surface photocatalytic reactions, and deepen our understanding on photochemistry on this surface.

Methyl formate

10.1021/acs.jpcc.9b02244

Cite

Citations (16)

Coverage Dependence of Methanol Dissociation on TiO₂(110)

The Journal of Physical Chemistry Letters (2015)

Shuo Liu An‐An Liu Bo Wen Ruidan Zhang Chuanyao Zhou

Although the photochemistry of methanol on TiO2(110) has been widely investigated as a prototypical model of the photocatalytic reaction of organic molecules, the most fundamental question of the adsorption state of methanol on TiO2(110) is still unclear. We have investigated the adsorption of methanol on TiO2(110) using sum frequency generation vibrational spectroscopy (SFG-VS) and density functional theory (DFT) calculations. The SFG results indicate the dissociation of methanol is highly dependent on the coverage. The DFT calculations suggest that the methanol prefers the partially dissociated structure at low coverage, whereas the second layer methanol, which is hydrogen-bonded to the bridge-bonded oxygen site, largely blocks the dissociation of the first layer methanol. Our results not only resolves a long-standing debate regarding the adsorption state of methanol on TiO2(110) but also provides a detailed insight into the adsorption structure and sheds light on the photochemistry on this surface at the molecular level.

10.1021/acs.jpclett.5b01417

Cite

Citations (66)

lncRNA H19 binds VGF and promotes pNEN progression via PI3K/AKT/CREB signaling

Endocrine Related Cancer (2021)

Meng Ji Yanli Yao An‐An Liu Ligang Shi Danlei Chen

10.1530/erc-18-0552e

Cite

Citations (0)

Surgical technique for a common hepatic artery which originates from the superior mesenteric artery and going behind the portal vein during a Whipple's procedure

Zhonghua gan-dan waike zazhi (2014)

Liu Ouyang An‐An Liu Bin Song Jun Hao Zhiyong Peng

Objective To discuss the technique in protecting a common hepatic artery when it originates from the superior mesenteric artery and going behind the portal vein during a Whipple's procedure.Methods The data of 4 patients with a common hepatic artery which originated from the superior mesenteric artery which went behind the portal vein and were admitted from September 2011 to May 2013 at the Department of Pancreatic Surgery of Changhai Hospital Affiliated to The Second Military Medical University were analyzed retrospectively.The method to protect the common hepatic artery anormaly was discussed.Results Following our technique,the common hepatic artery anormaly in the 4 patients was identified and preserved during the Whipple's procedure.The duration of surgery ranged from 160 to 215 min,with an average of 192 min.Intraoperative blood loss ranged from 200 to 800 ml,with an average of 400 ml,intraoperative blood transfusion ranged from 0 to 600 ml,with an average of 150 ml.The liver function did not change dramatically.The postoperative length of hospital stay ranged from 9 to 22 d,with an average of 17 d.All the 4 patients were discharged home smoothly.Conclusions Before a Whipple's procedure,the anatomy of the common hepatic artery should be known.It is necessary to have an enhanced CT scan or CTA,and we must read all the images carefully,and analyze the origin and the course of the common hepatic artery.It is necessary to occlude the gastroduodenal artery,touch the pulsation of the hepatic proper artery,dissect the root of the coeliac trunk carefully,and avoid cutting off any vessels when the dissection is not clear.These methods are beneficial to protect a common hepatic artery anormaly effectively. Key words: Anatomic variation; Common hepatic artery; Superior mesenteric artery; Whipple Procedure

Common hepatic artery

Superior mesenteric vein

Gastroduodenal artery

Whipple Procedure

10.3760/cma.j.issn.1007-8118.2014.05.013

Cite

Citations (0)

Frontispiz: In‐Sequence High‐Specificity Dual‐Reporter Unlocking of Fluorescent Probe Enables the Precise Identification of Atherosclerotic Plaques

Angewandte Chemie (2022)

Zhuo Ye Moxuan Ji Kefeng Wu Jie Yang An‐An Liu

Bioanalytik. Dingbin Liu et al. beschreiben in ihrem Forschungsartikel (e202204518) eine Reporterplattform, genannt iSHERLOCK, für den Fluoreszenznachweis von Lipidtröpfchen und HClO. Mittels iSHERLOCK wurden zwei Atherosklerosemarker quantitativ gemessen.

Sequence (biology)

Identification

10.1002/ange.202282962

Cite

Citations (0)

Infrared Free Induction Decay (IR-FID) of Non-Interfacial Origin Observed in the Interfacial Sum-Frequency Generation Vibrational Spectroscopy (SFG-VS)

Bojun Zhao Xing-Xing Peng Zhang Li Jingming Cao Shuyi Yang

We report the observation of infrared free induction decay (IR-FID) signal of the anti-symmetric modes around ~ 2350 cm-1 of the gaseous CO2 molecules in the air in the sum-frequency generation vibrational spectroscopy (SFG-VS) measurement from the gold surface. These signals appeared with time-dependent interference pattern in the 15-73 ps range and beyond after the time-zero of the SFG-VS process. The interference pattern was found to reflect the rotational coherence of the gaseous CO2 molecules. Similar IR-FID and rotational coherence was also observed for the symmetric and asymmetric stretching modes of gaseous H2O molecules in air. The gold surface in this case serves as the up-conversion agent with the visible pulse as the time-gate for the ultrafast IR-FID emissions. We tested this hypothesis by replacing the gold surface with a β-BBO (beta-barium borate, β-BaB2O4) and found a five orders of magnitude increase of the signal in the reflecting geometry. The up-conversion of the IR-FID radiation of non-interfacial origin into the SFG-VS signal also provides the mechanistic understanding of the ‘abnormal spectral bands’ in broadband SFG-VS induced by bulk absorption and refraction reported in the literature.

Free induction decay

10.26434/chemrxiv-2023-f47tv

Cite

Citations (1)