Yu Li

Fudan University

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Christoforos Moutafis

University of Manchester

Wenping Hu

Collaborative Innovation Center of Chemical Science and Engineering Tianjin

Qi Liu

Fudan University

Liqiang Li

Tianjin University

Wei Feng

Tianjin University

Deyang Ji

Tianjin University

Runze Chen

Hangzhou Normal University

Yiyu Feng

Tianjin University

Yongxu Hu

Tianjin University

Xiaosong Chen

Tianjin University

Cooperative Institutions

Chinese Academy of Sciences

127

Fudan University

105

Tianjin University

University of Chinese Academy of Sciences

Chinese Academy of Medical Sciences & Peking Union Medical College

Huashan Hospital

Sun Yat-sen University

Zhejiang University

Shanghai Jiao Tong University

Huazhong University of Science and Technology

Author Statistics

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Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials

The Lancet Oncology (2019)

Alexander Drilon Salvatore Siena Rafał Dziadziuszko Fabrice Barlési Matthew Krebs

10.1016/s1470-2045(19)30690-4

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Citations (407)

A new flow-level load balance in MPLS network based on distributable traffic

Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE (2007)

Kun Hao Zhigang Jin Yantai Shu Yu Li

Load distribution across multiple parallel paths is an important consideration. In many practical contexts, the aggregate traffic from source to sink may be such that no single link can carry the load. In an MPLS domain, this problem can be addressed by instantiating multiple paths. The main objective of this paper balances traffic at the flow level among the parallel Label Switched Paths (LSPs) in MPLS networks. Different from other proposals, our new framework is based on the distributable traffic (DT), where cross-traffic in real networks is considered, and each LSP is modeled as an M/G/1 processor-sharing queue. We define a flow to be a sequence of packet having the same identifier, and dispatch packet belonging to one flow to the same path, so the packet disorder problem is avoided effectively. This mechanism only needs to be implemented in the ingress LSRs and the egress LSRs. A new defined cost function is being used to distribute traffic to path. We computer the cost function based on the delay and packet loss of each LSPs, and minimize the cost function. The minimized cost function is inverse ratio to DT. If the cost function of a certain LSP is smaller, it means that more traffic can be distributed on this LSP. Extensive simulations using NS2 are performed with MPLS modules. Simulation results show that our approach so effective that the throughput is increased significantly and reduces the end-to-end delay and the packet drop rate, and it can distribute the traffic onto parallel LSPs more evenly and fairly.

Label Distribution Protocol

10.1117/12.730663

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Citations (0)

Seed-Assisted Synthesis of Graphene Films on Insulating Substrate

Materials (2019)

Qiqi Zhuo Yipeng Mao Suwei Lu Bolu Cui Yu Li

Synthesizing graphene at a large-scale and of high quality on insulating substrate is a prerequisite for graphene applications in electronic devices. Typically, graphene is synthesized and then transferred to the proper substrate for subsequent device preparation. However, the complicated and skilled transfer process involves some issues such as wrinkles, residual contamination and breakage of graphene films, which will greatly degrade its performance. Direct synthesis of graphene on insulating substrates without a transfer process is highly desirable for device preparation. Here, we report a simple, transfer-free method to synthesize graphene directly on insulating substrates (SiO2/Si, quartz) by using a Cu layer, graphene oxide and Poly (vinyl alcohol) as the catalyst, seeds and carbon sources, respectively. Atomic force microscope (AFM), scanning electronic microscope (SEM) and Raman spectroscopy are used to characterize the interface of insulating substrate and graphene. The graphene films directly grown on quartz glass can attain a high transmittance of 92.8% and a low sheet resistance of 620 Ω/square. The growth mechanism is also revealed. This approach provides a highly efficient method for the direct production of graphene on insulating substrates.

Graphene foam

10.3390/ma12091376

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Citations (10)

A new dithieno[3,2-b:2′,3′-d]thiophene derivative for high performance single crystal organic field-effect transistors and UV-sensitive phototransistors

RSC Advances (2023)

Yunpeng Lou Rui Shi Yu Li Ting Jiang Haoquan Zhang

Organic phototransistors (OPTs), as the basic unit for organic image sensors, are emerging as one of the most promising light signal detectors. High performance UV-sensitive phototransistors are highly desired for the detection of UV light. Herein, by introducing the anthracene group to the 2,6-positions of dithieno[3,2-b:2',3'-d]thiophene, we designed and synthesized a new dithieno[3,2-b:2',3'-d]thiophene derivative, 2,6-di(anthracen-2-yl)dithieno[3,2-b:2',3'-d]thiophene (2,6-DADTT). The single crystal structure of 2,6-DADTT presents classical herringbone packing with multiple intermolecular interactions, including S⋯S (3.470 Å), S⋯C (3.304 Å, 3.391 Å, 3.394 Å) and C-H⋯π (2.763 Å, 2.822 Å, 2.846 Å, 2.865 Å, 2.885 Å, 2.890 Å) contacts. Single crystal organic field-effect transistors (SC-OFETs) based on 2,6-DADTT reach a highest mobility of 1.26 cm2 V-1 s-1 and an average mobility of 0.706 cm2 V-1 s-1. 2,6-DADTT-based single crystal organic phototransistors (OPTs) demonstrate photosensitivity (P) of 2.49 × 106, photoresponsivity (R) of 6.84 × 103 A W-1 and ultrahigh detectivity (D*) of 4.70 × 1016 Jones to UV light, which are among the best figures of merit for UV-sensitive OPTs. These excellent comprehensive performances indicate its good application prospects in integrated optoelectronics.

Photosensitivity

Derivative (finance)

Crystal (programming language)

10.1039/d3ra00600j

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Citations (2)

CREDVW-Linked Polymeric Micelles As a Targeting Gene Transfer Vector for Selective Transfection and Proliferation of Endothelial Cells

ACS Applied Materials & Interfaces (2015)

Xuefang Hao Qian Li Juan Lv Yu Li Xiangkui Ren

Nowadays, gene transfer technology has been widely used to promote endothelialization of artificial vascular grafts. However, the lack of gene vectors with low cytotoxicity and targeting function still remains a pressing challenge. Herein, polyethylenimine (PEI, 1.8 kDa or 10 kDa) was conjugated to an amphiphilic and biodegradable diblock copolymer poly(ethylene glycol)-b-poly(lactide-co-glycolide) (mPEG-b-PLGA) to prepare mPEG-b-PLGA-g-PEI copolymers with the aim to develop gene vectors with low cytotoxicity while high transfection efficiency. The micelles were prepared from mPEG-b-PLGA-g-PEI copolymers by self-assembly method. Furthermore, Cys-Arg-Glu-Asp-Val-Trp (CREDVW) peptide was linked to micelle surface to enable the micelles with special recognition for endothelial cells (ECs). In addition, pEGFP-ZNF580 plasmids were condensed into these CREDVW-linked micelles to enhance the proliferation of ECs. These CREDVW-linked micelle/pEGFP-ZNF580 complexes exhibited low cytotoxicity by MTT assay. The cell transfection results demonstrated that pEGFP-ZNF580 could be transferred into ECs efficiently by these micelles. The results of Western blot analysis showed that the relative ZNF580 protein level in transfected ECs increased to 76.9%. The rapid migration of transfected ECs can be verified by wound healing assay. These results indicated that CREDVW-linked micelles could be a suitable gene transfer vector with low cytotoxicity and high transfection efficiency, which has great potential for rapid endothelialization of artificial blood vessels.

MTT assay

Polyethylenimine

PLGA

10.1021/acsami.5b02399

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Citations (55)

Back-End-of-Line Compatible 2T1C Memory Cell With InGaZnO Thin-Film Transistors and Hf_0.5Zr_0.5O₂-Based Ferroelectric Capacitors

IEEE Transactions on Electron Devices (2025)

Yize Sun Shucheng Zhang Qi Liu Yu Li Haoyu Lu

Ferroelectric capacitor

Line (geometry)

Film capacitor

10.1109/ted.2025.3529400

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Magnetization dynamics in synthetic ferromagnetic thin films

Physical review. B./Physical review. B (2021)

Harry Waring Yu Li Christoforos Moutafis I. J. Vera-Marun Thomas Thomson

Synthetic ferromagnets (SFMs) possess the same layer structure found in the widely studied synthetic antiferromagnets. This consists of two ferromagnetic (FM) layers separated by a nonmagnetic (NM) spacer forming the structure $\mathrm{F}{\mathrm{M}}_{1}/\mathrm{NM}/\mathrm{F}{\mathrm{M}}_{2}$, but SFMs describe the case where the interlayer exchange coupling promotes the parallel alignment of the magnetizations of the FM layers. The frequency and phase of the dynamic response of these structures depends sensitively on the interlayer exchange coupling as well as on the individual layer magnetizations. Through experiments and numerical simulations, we show that the dynamic response of the two ferromagnetic layers has an orthogonal dependence on the difference in layer magnetization and interlayer coupling allowing both parameters to be determined accurately. In addition, we are able to obtain the phases of the resonant modes, a hitherto challenging measurement, and thus show that the conventional acoustic and optical description does not fully capture the intricacies of SFM dynamics. These findings are directly applicable to the creation of tailored SFMs for spintronic devices such as STT/SOT-MRAM where magnetization and interlayer coupling are key parameters.

Magnetization dynamics

10.1103/physrevb.104.014419

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Citations (4)

Target Localization in Underwater Acoustic Sensor Networks

Congress on Image and Signal Processing (2008)

Biao Wang Yu Li Haining Huang Chunhua Zhang

The underwater target localization problem is one important application for underwater acoustic sensor networks. This paper, based on "underwater acoustic transmission theory", solves the target localization problem. The proposed algorithm firstly studies the principle of underwater acoustics and applies it to set up the model of underwater signal energy transmission. According to the model, the maximum likelihood (ML) method is used to estimate the target position based on measuring the received signal energy by sensor node. We also derivate the Cramer-Rao lower bound (CRB) based signal model in this paper. Lastly, our numerical simulation results have verified the feasibility of the proposed localization algorithm, and have studied the precision performance of the algorithm.

Underwater Acoustics

SIGNAL (programming language)

Underwater acoustic communication

Position (finance)

Acoustic sensor

10.1109/cisp.2008.74

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Citations (11)

Experimental and numerical study on different dual-fuel combustion modes fuelled with gasoline and diesel

Applied Energy (2013)

Binbin Yang Mingfa Yao Wai K. Cheng Yu Li Zunqing Zheng

Equivalence ratio

Nitrogen oxides

10.1016/j.apenergy.2013.07.034

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Citations (113)

Organic Phase‐Change Memory Transistor Based on an Organic Semiconductor with Reversible Molecular Conformation Transition

Advanced Science (2022)

Yongxu Hu Lei Zheng Jie Li Yinan Huang Zhongwu Wang

Phase-change semiconductor is one of the best candidates for designing nonvolatile memory, but it has never been realized in organic semiconductors until now. Here, a phase-changeable and high-mobility organic semiconductor (3,6-DATT) is first synthesized. Benefiting from the introduction of electrostatic hydrogen bond (S···H), the molecular conformation of 3,6-DATT crystals can be reversibly modulated by the electric field and ultraviolet irradiation. Through experimental and theoretical verification, the tiny difference in molecular conformation leads to crystalline polymorphisms and dramatically distinct charge transport properties, based on which a high-performance organic phase-change memory transistor (OPCMT) is constructed. The OPCMT exhibits a quick programming/erasing rate (about 3 s), long retention time (more than 2 h), and large memory window (i.e., large threshold voltage shift over 30 V). This work presents a new molecule design concept for organic semiconductors with reversible molecular conformation transition and opens a novel avenue for memory devices and other functional applications.

Organic semiconductor

10.1002/advs.202205694

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Citations (13)