Xin Cai

Zhejiang Sci-Tech University

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Zilong Zhou

Central South University

Shenglie Wang

Wuhan National Laboratory for Optoelectronics

Shi‐Xiong Liu

Lanzhou University

C. Z. Yuan

University of Chinese Academy of Sciences

Jinsong Liu

Shanghai Electric (China)

L. Y. Dong

Institute of High Energy Physics

Jinsong Liu

Chinese Academy of Sciences

F. De Mori

University of Turin

Shengdong Nie

University of Shanghai for Science and Technology

H. L.

Yunnan University

Cooperative Institutions

Institute of High Energy Physics

953

Chinese Academy of Sciences

450

University of Chinese Academy of Sciences

388

China Center of Advanced Science and Technology

250

COMSATS University Islamabad

242

University of Science and Technology of China

238

Beihang University

173

Henan University

170

Central South University

163

Inner Mongolia University

161

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Perioperative Fluoroquinolone Treatment Deteriorates Prognosis Following Coronary Artery Bypass Grafting

Journal of Cardiovascular Development and Disease (2022)

Min Zhang Lijuan Jian Xinping Min Bowen Li Xin Cai

Background: Former studies have revealed that fluoroquinolone (FQ) can induce aortic expansion and rupture. While FQ is widely used in perioperative anti-infection therapy, its impact on graft patency and patient survival is unknown. Methods: Coronary artery bypass grafting (CABG) data were extracted from the MIMIC-III database. Chi-square tests, Fisher’s exact tests, t-tests, or ANOVAs were used to compare baseline data between groups determined by FQ therapy status, depending on the data type. Propensity score matching was used to establish a balanced cohort. Cox regression was used to investigate the impact of FQ on CABG patient survival, whereas paired t-tests were used to analyze secondary results. Results: Of the 5030 patients who underwent CABG, 937 (18.6%) received oral or intravenous FQ therapy. Using propensity score matching, these 819 patients were successfully matched with 819 controls in a 1:1 ratio. Cox regression showed that FQ significantly decreased survival among CABG patients (HR: 1.62, 95% CI: 1.21−2.15, p = 0.001). Furthermore, FQ usage was associated with longer hospitalization (<0.0001), ICU duration (<0.0001), ventilation period (<0.0001), and duration of vasopressor administration (<0.0001). Conclusions: Perioperative FQ therapy was associated with worse prognosis and a more difficult recovery among patients with CABG.

10.3390/jcdd9060173

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The role of carbon ion radiotherapy for unresectable locally recurrent rectal cancer: a single institutional experience

Research Square (Research Square) (2020)

Xin Cai Yueyao Du Zheng Wang Ping Li Zhan Yu

Abstract Background Treatment for locally recurrent rectal cancer after surgery is still a challenge. With the physical and biological advantages, carbon-ion radiotherapy (CIRT) could be a choice for these patients. The purpose of this study was to investigate the efficacy and safety of CIRT for unresectable locally recurrent rectal cancer in Chinese patients. Methods Date from 25 patients with unresectable locally recurrent rectal cancer treated by CIRT from July 2015 to April 2019 were analyzed retrospectively. The endpoints of this study were overall survival (OS), local control (LC) and acute and late toxicity. Results With the median follow-up of 19.6 (range 5.1–52.5) months, data of all 25 patients were collected. Median prescribed dose for tumor was 72 Gy (relative biologic efficacy (RBE)) (range 48-75.6 Gy (RBE)). The LC rates at 1 and 2 years were 90.4% and 71.8%. Overall LC at 1- and 2-year were 76.2% and 30.5% for 9 patients whose prescribed tumor doses of CIRT < 66 Gy (RBE), 100% and 100% for 16 patients whose prescribed doses of CIRT ≥ 66 Gy (RBE). Patients received ≥ 66 Gy (RBE) had obviously better LC rates than those received < 66 Gy (RBE) (P = 0.001). The OS rates at 1 and 2 years were 82.9% and 65.1%, respectively. No acute toxicity over grade 2 was observed, grade 3 late toxicity were observed in 3 patients: gastrointestinal toxicity (n = 1), neuropathy (n = 1), pelvic infection (n = 1). No Grade 4 or higher toxicity was observed. Conclusion Our study shows that CIRT is effective for unresectable locally recurrent rectal cancer patients with acceptable toxicity.

Carbon Ion Radiotherapy

10.21203/rs.3.rs-38923/v1

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Measurements of the absolute branching fractions and CP asymmetries for D+→KS,L0

Physical review. D/Physical review. D. (2019)

F. De Mori M. N. Achasov S. Ahmed M. Albrecht A. Amoroso

Using e+e− collision data corresponding to an integrated luminosity of 2.93 fb−1 taken at a center-of-mass energy of 3.773 GeV with the BESIII detector, we determine the absolute branching fractions B(D+→K0SK+)=(3.02±0.09±0.08)×10−3, B(D+→K0SK+π0)=(5.07±0.19±0.23)×10−3, B(D+→K0LK+)=(3.21±0.11±0.11)×10−3, and B(D+→K0LK+π0)=(5.24±0.22±0.22)×10−3, where the first and second uncertainties are statistical and systematic, respectively. The branching fraction B(D+→K0SK+) is consistent with the world average value and the other three branching fractions are measured for the first time. We also measure the CP asymmetries for the four decays and do not find a significant deviation from zero.Received 14 December 2018DOI:https://doi.org/10.1103/PhysRevD.99.032002Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. Funded by SCOAP3.Published by the American Physical SocietyPhysics Subject Headings (PhySH)Lifetimes & widthsResearch AreasQuasiparticles & collective excitationsLifetimes & widthsResearch AreasAtomic & molecular structureAtomic spectraLifetimes & widthsResearch AreasNuclear structure & decaysLifetimes & widthsResearch AreasLifetimes & widthsNuclear spin & parityParticle interactionsNuclear Physics

Branching (polymer chemistry)

Branching fraction

10.1103/physrevd.99.032002

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A Study on the Elderly-Orientation of Urban Public Space

OALib (2022)

Yuanhong Peng Zibiao Cheng Ping Fu Liya Gao Xin Cai

At present, the aging population in cities is growing sharply, and the problem of elderly-oriented urban public spaces is gradually coming to the fore and urgently needs noticing and addressing.As an illustration, we may take Dazhou City as an example.Conclusion can be drew form the questionnaires and offline visits that the elderly generally have difficulties in traveling, shopping and medical care, affected by the lack of community infrastructure, their physical condition, living habits and knowledge structure, etc.We propose to improve the adaptability of the elderly, build a comprehensive system of elderly services, create an elderly-oriented urban space as well as an atmosphere of respect for them to level their well-being index up and settle the issue of elderly-oriented retrofitting of urban public space.

Public space

10.4236/oalib.1109616

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An image encryption method based on logistic chaotic mapping and DNA coding

Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE (2020)

Jiayu Lin Zhao Kangnan Xin Cai Li Danning Zuxi Wang

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Nano-material and Microelectrode Biosensors

Xin Cai

A novel microelectrodes integrated biosensor using MEMS technology is reported, nano particals are deposited on the microelectrodes using electrochemical method. The characteristics of the biosensor including stability, sensitivity and response time are studied after nano material modification. This biosensor with high performance of nano material will have potential application in the field of biological medicine.

Multielectrode array

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Research on Enhancing the Prediction of Credit Risk in Commercial Banks Based on Implied NPL Ratios

Jinrong jianguan yanjiu (2012)

Xin Cai

This paper discusses the implementation of implied NPL ratio after introducing and comparing the techniques of credit risk evaluation in commercial banks.By collecting and calculating financial data of listed nonfinancial firms,we make a comparable analysis between the implied NPL ratios of listed non-financial corporations and the NPL ratios of commercial banks both in china and abroad.The paper also analyzes how to enhance the effectiveness in predicting credit risk in commercial banks based on the implied NPL ratios.We find that although there are limitations,this indicator is to a certain extend a precursor and referable in revealing the credit risk of the non-financial firms,and can help in the prediction of credit risk of commercial banks.

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[In vitro study on arsenic trioxide-induced apoptosis of retinoic acid resistant acute promyelocytic leukemia cell line(MR-2)].

PubMed (1998)

Xin Cai Ping Jia Shi X

To study the possible mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL).Retinoic acid resistant APL cell line MR-2 was used as in vitro model. The effect of As2O3 on MR-2 cell line was observed by cell viability, cell growth, cell morphology, flow cytometry assay, NBT reduction test and immunofluorescence analysis.1.0 mumol/L of As2O3 could induce apoptosis of MR-2 cells and it correlated with the degradation of PML-RAR alpha fusion protein.The therapeutic effect of As2O3 for APL possibly differs from that of ATRA, however, PML-RAR alpha fusion protein may be the target of both the therapy.

Arsenic Trioxide

Viability assay

Tretinoin

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Contents list

Reaction Chemistry & Engineering (2024)

Yaqi Wang Jiawei Wu Wenju Zhang Linyun Zhong Dan Zhang

10.1039/d4re90021a

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