Bu arastirmanin amaci, gecmiste uzun yillar idari ve mali acidan kamu muessesesi niteliginde hizmet veren, gunumuzdeyse bir vakif universitesine bagli Tip Fakultesi’nin Fizik Tedavi ve Rehabilitasyon (FTR) Anabilim Dali’na ait bakim ve tedavi servislerinin maliyet yapisi ve analizidir. Calismada, Vergi Usul Kanunu ve diger ilgili mevzuat geregince tutulan kayit ve raporlara dayali muhasebe verileri kullanilmistir. Bunlar, Microsoft Excel programi kullanilarak geleneksel yontemlerle cozumlendikten sonra, bilgisayar istatistik programinda Korelasyon (iliski) testi yapilmis, veri guvenligiyse Alfa testiyle yapilmistir. ‘Toplam maliyet’in yarisindan fazlasinin ‘isgucu gideri’nden olusmasina ragmen, bu iki degisken/gider arasinda anlamli bir iliski bulunamamistir.
Background: Lung cancer is the most common cancer in males worldwide. The principal mode of treatment in the early stage of non-small cell lung cancer (NSCLC) is surgery. However, five-year survival is only about 15% for all stages. The aim is to investigate the effect of daily low dose cisplatin concurrently with radiation therapy in advanced NSCLC patients with poor performance status. Materials and Methods: Ten patients diagnosed as inoperable Stage IIIB NSCLC with comorbid disease were assessed retrospectively in Bezmialem Vakif University, Faculty of Medicine, Department of Radiation Oncology, between 2011 to 2013. ECOG performance status was between 3 and 4. Cisplatin was administered at $6mg/m^2$ daily, for 5 days a week concurrently with radiotherapy using 160-200 cGy daily fractions, 54 Gy being the lowest and 63 Gy being the highest dose. Results: Complete response at the primary tumour site was obtained in 20% patients. Grade I esophagitis was seen 70 percent of patients, and the grade II haematological toxicity rate was 20 %. Median survival time was 7 months. Conclusions: Median survival time was reasonable, despite the patients ECOG performance status of 3-4, which is similar to groups even without comorbid disorders in comparison to other published papers in the literature. Acceptable toxicity, high response rates and quality of life of patients are the other favourable features.
Transient osteoporosis of the hip is rare condition of unclear etiology characterized by hip pain, limited osteopenia on plain radiography and characteristic magnetic resonance image findings.The etiopathogenesis is unclear.We aimed to present 25 years old patient with transient osteoporosis of the hip occurred due to surgery and immobilization in this article.(
Our aim is to evaluate serum Raftlin levels as a biomarker for diagnosing and monitoring disease activity in patients with axial spondyloarthritis (axSpA) and Psoriatic arthritis (PsA). This trial included 40 axSpA patients, 40 PsA patients, and 40 healthy participants as the control group. Disease activity was assessed with Ankylosing Spondylitis Disease Activity Score for axSpA patients and The Disease Activity Index for Psoriatic Arthritis for PsA patients. The Spondyloarthritis Research Consortium of Canada index, health assessment questionnaire-disability index, and numeric rating scale were used to evaluate the enthesitis severity, disability, and pain status of all patients. Serum Raftlin levels were determined using the ELISA method. The 3 groups had no statistical differences regarding gender, age, weight, height, BMI, educational status, and exercise habits. The axSpA group had higher Raftlin levels than the PsA and control groups, and Raftlin levels were statistically significant in predicting the likelihood of axSpA. We found no statistically significant differences between the PsA and control groups. We found no statistically significant difference in Raftlin levels in HLA-B27 positive versus HLA-B27 negative patients in both axSpA and PsA groups. Our results also did not detect any correlation of Raftlin levels with Ankylosing Spondylitis Disease Activity Score, C-reactive protein, erythrocyte sedimentation rate, health assessment questionnaire-disability index, numeric rating scale, and Spondyloarthritis Research Consortium of Canada index in axSpA patients. Receiver operating characteristic analysis determined that Raftlin level ≥ 6.31 ng/mL discriminates axSpA from normal individuals with 92.5% sensitivity, 59% specificity, and an area under the curve of 0.738. Our results demonstrate that although serum Raftlin levels are elevated in axSpA patients, Raftlin cannot be used as an alone diagnostic marker for axSpA. Furthermore, it was not found to be related to the monitoring of disease activity, the level of pain, disability, or severity of enthesitis. This study is prospectively registered at www.clinicaltrials.gov (ID: NCT05771389).
Background: Cervical disc herniation (CDH) is the most common cause of cervical radiculopathy and could overlap with fibromyalgia (FM). Objective: The primary aim of the present study was to investigate the prevalences of FM and widespread pain in pa
To determine the cardiovascular risk (CVR) in patients with rheumatoid arthritis (RA) and its correlation with disease activity and functional ability by using the Framingham risk score (FRS) and to compare the CVR of the RA patients with the control group with the help of the FRS. Materials and methods: Seventy-four RA patients, who were in conformity with the criteria of the American College of Rheumatology, were included in this study at Bezmialem Vakıf University Hospital. A total of 39 subjects without inflammatory arthritis were included as the control group. The FRS was calculated by evaluating age, smoking habits, diabetes, cholesterol and blood pressure measurements. The disease activity score-28 (DAS-28) and the health assessment questionnaire (HAQ-DI) were applied to the RA patients. Results: We could not find any significant difference between the case and control groups in terms of FRS. The means of erythrocyte sedimentation rate (ESR) and blood pressure of participants in the study group were significantly higher than those of the control group. There was not any significant difference in terms of C-reactive protein (CRP) and cholesterol levels between the groups. DAS-28, HAQ-DI, CRP, ESR, and disease duration were not significantly correlated with FRS. Conclusion: For patients who have inflammatory arthritis, new risk score calculation that consists of other disease-specific risk factors, in addition to traditional ones, is needed.
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