A. Müller

Johns Hopkins Medicine

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H. Ditschuneit

Universität Ulm

Peter Malfertheiner

Otto-von-Guericke University Magdeburg

Tanya J.W. McDonald

Johns Hopkins Medicine

Luisa A. Diaz‐Arias

Johns Hopkins Medicine

Mackenzie C. Cervenka

Johns Hopkins Hospital

Markus W. Büchler

Heidelberg University

U Bárta

Friedrich Schiller University Jena

Ralf Dittrich

Comprehensive Cancer Center Erlangen

Bardia Nourbakhsh

Johns Hopkins Medicine

G Wessel

Friedrich Schiller University Jena

Cooperative Institutions

Friedrich-Alexander-Universität Erlangen-Nürnberg

Universitätsklinikum Erlangen

Johns Hopkins Medicine

Johns Hopkins University

Johns Hopkins Hospital

Heidelberg University

Friedrich Schiller University Jena

Comprehensive Cancer Center Erlangen

Olgahospital

Universitäts Frauenklinik

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Myome - Teil 1

Geburtshilfe und Frauenheilkunde (2004)

A. Müller FC Thiel Helge Binder Reiner Strick Ralf Dittrich

Myome des Uterus sind die häufigsten soliden Tumoren der Frau. Sie sind hormonabhängig und durch ein gutartiges Wachstum charakterisiert. Bei ca. 20 - 30 % aller Frauen über 30 Jahre finden sich Myome des Uterus. Die Zahl steigt bei 40-jährigen Frauen auf über 40 % an [[150]]. Bei 1245 durchgeführten Hysterektomien wiesen 69 % der Patientinnen Myome auf [[74]]. Durch ihre Hormonabhängigkeit

10.1055/s-2004-830411

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Citations (10)

[Hydroxyproline excretion in psoriasis and psoriatic arthritis].

PubMed (1990)

Gert Hein B Knopf U Bárta A. Müller G Wessel

In the morning urine of 24 patients with psoriasis and that of 24 patients with psoriatic arthritis, we determined the excretion of hydroxyproline (mg HP/mumol crea), after preceding diet low in collagen. Surprisingly, psoriatic patients without articular involvement showed a significantly higher excretion of HP than those with psoriatic arthritis. Further differentiation revealed that there were no clear-cut correlations between the amount of HP excretion and the activity of the articular process; we proved, however, that the amount of HP excretion was definitely related to the activity of the skin eruptions in both groups of patients. We discuss whether an osteopathy pathogenetically associated with the skin disease (irrespective of synovitis in psoriatic arthritis) may possibly be responsible for these results.

Hydroxyproline

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Fluorescein Dilaurate Serum Test

Pancreas (1987)

Peter Malfertheiner Markus W. Büchler A. Müller H. Ditschuneit

The value of a modified fluorescein dilaurate (FDL) serum test for the detection of pancreatic exocrine insufficiency was investigated in 89 patients with and without pancreatic disease. This test modification with fluorescein serum determination following metoclopramide (10 mg) and secretin (1 U/kg) i.v. injection appeared efficacious in a pilot study in six healthy volunteers. Individual peak fluorescein serum concentration was achieved within 180 min after the test meal in 96% of all subjects studied. Peak fluorescein serum concentration within this time period allowed the best discrimination between normal and abnormal pancreatic function. Sensitivity in detection of chronic pancreatitis was 86% (38 of 44 patients) when the lower normal fluorescein serum concentration was considered 4.5 μg/ml (this value corresponds to mean – 2 SD). The specificity of this test in detecting chronic pancreatitis was 100% when healthy controls were considered, but fell to 78% when patients with different gastrointestinal disorders, including those with secondary pancreatic insufficiency, were included. The correlation between serum and urinary fluorescein determination was significant (r = 0.61; p <0.01). Duodenal bicarbonate output/h after secretin also showed a significant correlation with peak fluorescein serum concentration (r = 0.79; p <0.001).

Secretin

Microgram

Pancreatic Disease

10.1097/00006676-198701000-00009

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Citations (49)

The effect of anti-seizure medications on lipid values in adults with epilepsy

Epilepsy & Behavior (2023)

A. Müller Luisa A. Diaz‐Arias Mackenzie C. Cervenka Tanya J.W. McDonald

Dyslipidemia

Valproic Acid

10.1016/j.yebeh.2023.109260

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Citations (2)

Tsutsugamushi-Fieber: Seltene Rickettsiose nach Aufenthalt auf den Philippinen

DMW - Deutsche Medizinische Wochenschrift (2008)

B. P. Fischer A. Müller Richard Strauß H. T. Schneider Eckart G. Hahn

Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study

Leukocytosis

Atypical pneumonia

10.1055/s-2007-1024011

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Citations (6)

Visceral leishmaniasis: personal observation and review of its epidemiology, clinical features and therapy.

Klinische Pädiatrie (1990)

R. Deckerhoff A. Müller Ulrike Bode

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[Undesirable results of rest in skeletal tuberculosis in children].

PubMed (1957)

A. Müller

Rest (music)

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[The fluorescein dilaurate serum test following metoclopramide and secretin stimulation for evaluating pancreatic function. Contribution to the diagnosis of chronic pancreatitis].

PubMed (1987)

Peter Malfertheiner MW Büchler A. Müller H. Ditschuneit

A new method of exocrine pancreatic function testing is described. After oral administration of a standard meal containing fluorescein dilaurate (FDL) metoclopramide (10 mg) and secretin (1 U/kg) are given as intravenous bolus injection. The best discrimination between normal and abnormal pancreatic function was found to be the individual peak serum fluorescein concentration within 180 minutes. 184 patients were studied and divided into 4 groups according to the final diagnosis: group 1: 44 healthy controls; group 2: 87 patients with chronic pancreatitis; group 3: 21 patients with different pancreatic diseases; group 4: 32 patients with different gastrointestinal disorders. Sensitivity of the FDL serum-test in detecting chronic pancreatitis was 87%, specificity was 97%. Considering patients with different gastrointestinal disorders specificity dropped to 77%. FDL serum-test revealed superior as compared to the FDL urine test. Correlation between FDL serum-test and secretin ceruletide test was significant (r = 0.72, p less than 0.001).

Secretin

Metoclopramide

Pancreatic function

Bolus (digestion)

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Citations (10)

Ocrelizumab alters the circulating metabolome in people with relapsing–remitting multiple sclerosis

Annals of Clinical and Translational Neurology (2024)

Fatemeh Siavoshi Dimitrios C. Ladakis A. Müller Bardia Nourbakhsh Pavan Bhargava

Circulating metabolite levels are altered in multiple sclerosis (MS) and are associated with MS severity. However, how metabolic profiles shift following highly efficacious therapies, like ocrelizumab remains unclear.

Relapsing remitting

Ocrelizumab

Metabolome

10.1002/acn3.52167

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Citations (2)

The effect of the modified Atkins diet and anti-seizure medications on lipid marker levels in adults with epilepsy

Nutritional Neuroscience (2024)

A. Müller Luisa A. Diaz‐Arias Mackenzie C. Cervenka Tanya J.W. McDonald

Some anti-seizure medications (ASMs) are known to induce liver enzymes and impact lipid values that include total cholesterol (TC), low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), and triglyceride (TG). In addition, use of ketogenic diet therapies, including the modified Atkins diet (MAD), has also influenced lipids. Here, we explored the combined impact of enzyme inducing ASMs (EIASMs) and MAD on lipid values in adults with epilepsy.

10.1080/1028415x.2024.2397624

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