Mohamed Soliman

Northern Border University

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Nadeem Kizilbash

Northern Border University

Afzal Nikaein

Medical City Dallas Hospital

M E Fisfalen

University of Chicago

Leslie J. DeGroot

University of Chicago

Jamith Basha

Northern Border University

Sana A. AlSadrah

Saad Specialist Hospital

Nida Suhail

Northern Border University

Muhammad Siddiq

Quaid-i-Azam University

Gayane Melikyan

Weill Cornell Medical College in Qatar

Alan Menter

Baylor Medical Center at Garland

Cooperative Institutions

Northern Border University

Mansoura University

Weill Cornell Medical College in Qatar

Cornell University

Memorial Sloan Kettering Cancer Center

Hamad Medical Corporation

Hamad General Hospital

Harvard University

Quaid-i-Azam University

University of Chicago

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Papers

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Cellular and molecular association of HLA antigens with psoriasis

Human Immunology (1991)

Afzal Nikaein Mohamed Soliman

Association (psychology)

10.1016/0198-8859(91)90169-a

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Citations (0)

O038 Comparison of responses to different pollen challenges in the environmental exposure unit (EEU)

Annals of Allergy Asthma & Immunology (2016)

Anne K. Ellis Mohamed Soliman Lisa Steacy Saffron French

10.1016/j.anai.2016.09.398

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Citations (1)

Multistrain Probiotics and Telomere Length in Type 2 Diabetes: A 24-Week Randomized Controlled Trial

Life (2025)

Venkata Chaithanya Janardanan Kumar K.V. Leela H Baig Mohamed Soliman

This 24-week randomized controlled trial aimed to evaluate the impact of multistrain probiotic supplementation on telomere length in patients with type 2 diabetes (T2DM). The study also assessed secondary outcomes including high-sensitivity C-reactive protein (hs-CRP) and glycated hemoglobin (HbA1c). A total of 124 participants with T2DM were randomly assigned to either a probiotic group (n = 62) or a placebo group (n = 62). Participants in the probiotic group consumed a supplement containing fourteen live microbial strains, including Lactobacillus plantarum, L. fermentum, L. acidophilus, L. casei, L. rhamnosus, L. reuteri, L. salivarius, L. paracasei, L. gasseri, Bifidobacterium bifidum, B. lactis, B. breve, Streptococcus thermophilus, and Saccharomyces boulardii, with each strain providing 2.148 billion CFUs per capsule, totaling 30 billion CFUs. The placebo group received vitamin B12 capsules without probiotics. The primary outcome was telomere length, and secondary outcomes included hs-CRP and HbA1c levels. Data were analyzed using intention-to-treat (ITT) and per-protocol (PP) methods. The probiotic group exhibited a statistically significant decrease in telomere shortening compared to the placebo group (p < 0.001). The hs-CRP levels decreased more significantly in the probiotic group (p < 0.001), suggesting potential anti-inflammatory effects. The HbA1c levels improved in the probiotic group, with a reduction of 0.44% (p = 0.004). An age-stratified analysis revealed more substantial improvements in the 30-49 years cohort, which showed greater reductions in telomere shortening, inflammatory markers, and metabolic indicators compared to the 50-69 years group. Multistrain probiotic supplementation shows potential benefits in reducing telomere shortening and improving glycemic control. However, further long-term studies are needed to understand the underlying mechanisms and therapeutic implications of probiotics in T2DM. This trial was registered at the Clinical Trials Registry-India (CTRI/2023/07/055647).

10.3390/life15020311

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Copper Oxide Nanoparticles Stimulate Cellular Damage and Histological Architecture Deterioration in Tissues of Culex Pipiens Larvae (Diptera: Culicidae).

Egyptian Academic Journal of Biological Sciences. D, Histology and Histochemistry (2022)

Mona Ragheb Mohamed Soliman Riham Taha

, is one of the considerable vector-borne diseases widely distributed all over the world. The extensive use of synthetic insecticides caused various human health hazardous, insect resistance and environmental pollution. As an alternative control strategy, nanoparticle applications in insect management are mandatory. Mainly, the aim of this current study is to elucidate the toxic effect of copper oxide nanoparticles (CuONPs) on larval tissues of Culex pipiens regarding the histological and cellular damage aspects. The lethal concentrations LC10, LC25, LC50 and LC90 were determined from the established regression log concentrate-response lines after 24 hours of treatment. Four replicates were considered for each concentration where twenty-five third instar larvae were involved for each replicate. Results revealed significant increase in mortality rate upon increasing copper oxide nanoparticles (CuONPs) concentrations which recorded 0.040, 0.099, 0.268 and 1.767 mg/ ml for LC10, LC 25, LC50, and LC90 respectively. Data in this study showed a significant increase in cellular damage enzyme levels namely, lipid peroxidase and nitric oxide, and a significant decrease in levels of total protein while, an increase in albumin proportions were detected in tissue homogenates of treated larvae of the increasing mentioned lethal CuONPs concentrations. Meanwhile, histological studies implied severe deterioration in tissue architecture of the treated larvae which increases markedly as the CuONPs concentration increase as well. In conclusion, CuONPs increase the cellular damage and deteriorate the histological structure of tissues of Culex pipiens larvae which render them promising and smart larvicidal agents.

Culex pipiens

Environmental Pollution

10.21608/eajbsd.2022.249341

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Citations (2)

Reduced Graphene Oxide-Zinc Sulfide Nanocomposite Decorated with Silver Nanoparticles for Wastewater Treatment by Adsorption, Photocatalysis and Antimicrobial Action

Molecules (2023)

Hina Naeem Hafiz Muhammad Tofil Mohamed Soliman Abdul Hai Syeda Huma H. Zaidi

Reduced graphene oxide nanosheets decorated with ZnS and ZnS-Ag nanoparticles are successfully prepared via a facile one-step chemical approach consisting of reducing the metal precursors on a rGO surface. Prepared rGO-ZnS nanocomposite is employed as an adsorbent material against two model dyes: malachite green (MG) and ethyl violet (EV). The adsorptive behavior of the nanocomposite was tuned by monitoring some parameters, such as the time of contact between the dye and the adsorbent, and the adsorbent dose. Experimental data were also simulated with kinetic models to evaluate the adsorption behavior, and the results confirmed that the adsorption of both dyes followed a pseudo 2nd order kinetic mode. Moreover, the adsorbent was also regenerated in a suitable media for both dyes (HCl for MG and ethanol for EV), without any significant loss in removal efficiency. Ag doped rGO-ZnS nanocomposite was also utilized as a photocatalyst for the degradation of the selected organic contaminant, resorcinol. The complete degradation of the phenolic compound was achieved after 60 min with 200 mg of rGO-ZnS-Ag nanocomposite under natural sunlight irradiation. The photocatalytic activity was studied considering some parameters, such as the initial phenol concentration, the photocatalyst loading, and the pH of the solution. The degradation kinetics of resorcinol was carefully studied and found to follow a linear Langmuir-Hinshelwood model. An additional advantage of rGO-ZnS and rGO-ZnS-Ag nanocomposites was antibacterial activity against Gram-negative bacterium, E. coli, and the results confirmed the significant performance of the nanocomposites in destroying harmful pathogens.

Malachite green

Resorcinol

Langmuir adsorption model

Zinc sulfide

Brilliant green

10.3390/molecules28030926

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Citations (25)

A study on Trichomoniasis vaginalis and female infertility.

PubMed (2001)

Ahmed Elshazly H M El-Naggar Mohamed Soliman Mohamed Abd Ellatif Elnegeri H E El-Nemr

A total of 280 patients, 240 infertile and 40 pregnant were subjected to thorough history taking, general and local examination for exclusion of organic lesion, laboratory investigations to exclude parasitic, bacterial and fungal infections. Sterile vaginal swab from the posterior fornix was taken, and examined by wet smear preparation, Giemsa staining and cultivation on C.P.L.M. medium for trichomoniasis infection. The mean age of the infertile group was 25.75+/-3.92, and of the control group was 21.6+/-2.38 (in years). The mean duration of infertility was 2.81+/-1.51 (years). Out of 240 infertile women, 18.75% complained of discharge, 17.5% itching, 15.42% dysuria, 14.58% dyspareunia, and 10% had cervical lesion. Of the 40 controls, 5% complained of discharge, 2.5% complained of itching, dysuria, dyspareunia, but none had cervical lesion. Of the total cases (280), 36 (12.9%) had T. vaginalis. The clinical data observed were significantly higher among the infertile group than the control group. Cultures were positive in 14.58% of the infertile group and 2.5% in the control group. The difference between the 2 groups was statistically significant. No doubt, T. vaginalis plays an important role in female infertility.

Dysuria

Trichomoniasis

Giemsa stain

Vaginal discharge

Female infertility

Source

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Citations (51)

Potential Value of Liver Enhancing Tumor Burden at CT to Predict Survival after Intra-arterial Treatment for Neuroendocrine Liver Metastases

Radiology Imaging Cancer (2023)

Mohamed Soliman

Liver tumor

10.1148/rycan.239008

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Characterization of T-cell clones generated from skin of patients with psoriasis

Journal of the American Academy of Dermatology (1993)

Afzal Nikaein Lynn Morris Charles M. Phillips Mohamed Soliman Guido Ordonez

clone (Java method)

Skin biopsy

10.1016/0190-9622(93)70073-3

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Citations (17)

Antenatal sonographic diagnosis of cebocephaly.

Journal of Ultrasound in Medicine (1988)

Albert L. Bundy Hart G.W. Lidov Mohamed Soliman Peter M. Doubilet

10.7863/jum.1988.7.7.395

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Citations (4)

MicroRNA as a Biomarker for Diagnostic, Prognostic, and Therapeutic Purpose in Urinary Tract Cancer

Processes (2021)

Amro M. Soliman Mohamed Soliman Srijit Das Seong Lin Teoh

The incidence of urologic cancers, including kidney, upper tract urothelial, and bladder malignancies, is increasing globally, with a high percentage of cases showing metastasis upon diagnosis and low five-year survival rates. MicroRNA (miRNA), a small non-coding RNA, was found to regulate the expression of oncogenes and tumor suppressor genes in several tumors, including cancers of the urinary system. In the current review, we comprehensively discuss the recently reported up-or down-regulated miRNAs as well as their possible targets and regulated pathways involved in the development, progression, and metastasis of urinary tract cancers. These miRNAs represent potential therapeutic targets and diagnostic/prognostic biomarkers that may help in efficient and early diagnosis in addition to better treatment outcomes.

Diagnostic biomarker

10.3390/pr9122136

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