Cong Lin

Jiangxi Science and Technology Normal University

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i-10 index

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Yuhong Zhang

Zhejiang University

Zhanxiang Liu

Beijing Tongren Hospital

Jinzhong Yao

Jiaxing University

Binjie Wang

Henan University

Liang Shen

Zhengzhou University

Ruokun Feng

Shaoxing University

Zhengkai Chen

Zhejiang Sci-Tech University

Danyang Li

Affiliated Hospital of Qingdao University

Fei Gao

Jiangxi Science and Technology Normal University

Yue Liu

Zhongyuan University of Technology

Cooperative Institutions

Jiangxi Science and Technology Normal University

Zhejiang University

Chinese Academy of Sciences

Jiangsu Normal University

Peking University

Tianjin University

Hangzhou Xixi hospital

University of Chinese Academy of Sciences

Fudan University

National University of Singapore

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The efficient in‐situ reduction and cyclization reaction of aromatic aldehyde, 1,3‐cyclopentanedione (tetronic acid), and nitro‐compound under SnCl₂·2H₂O‐THF medium

Applied Organometallic Chemistry (2017)

Hui Xu Lei Li Lei Dai Kaimin Mao W. W. Kou

An efficient in‐situ reduction and cyclization reaction for the synthesis of pyrazolo[4,3‐ f ]quinoline, pyrazolo[3,4‐ f ]quinoline, and pyrazolo[3,2‐ f ]quinoline derivatives directly form 5‐nitroindazole, 6‐nitroindazole and 5‐nitroindole in the presence of SnCl 2 ·2H 2 O was reported. Compared to traditional synthetic methods, this approach has the advantages of stable reagents, easy obtaining raw material, and high yields. In this research, SnCl 2 ·2H 2 O is the efficient reducing agent for the in‐situ reduction and cyclization reaction of nitro‐compound. In addition, this process provided an alternative approach for the synthesis of target compounds.

Quinoline

Nitro compound

Reaction conditions

10.1002/aoc.4194

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Citations (7)

ChemInform Abstract: Synthesis and Biological Evaluation of 3‐Hydroxymethylpyrimido(1,6‐c)( 1,3)oxazine Derivatives.

ChemInform (1997)

L.‐Y. HSU Cong Lin

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.199717155

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Citations (0)

ChemInform Abstract: Synthesis of 2,3‐Dihydro‐1H‐indazoles by Rh(III)‐Catalyzed C—H Cleavage of Arylhydrazines.

ChemInform (2014)

Jinzhong Yao Ruokun Feng Cong Lin Zhanxiang Liu Yuhong Zhang

Abstract A series of 2,3‐dihydro‐1H‐indazoles is prepared via a Rh‐catalyzed activation of arylhydrazines and olefin addition.

Cleavage (geology)

10.1002/chin.201501147

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Direct ortho-Thiolation of Arenes and Alkenes by Nickel Catalysis

Organic Letters (2015)

Cong Lin Danyang Li Binjie Wang Jinzhong Yao Yuhong Zhang

The direct thiolation of arenes and alkenes with diaryl disulfides was developed by nickel catalysis. The reaction displayed exceptional compatibility with a wide range of functional groups to regioselectively give the diaryl sulfides and alkenyl sulfides in high yields.

10.1021/acs.orglett.5b00337

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Citations (152)

Palladium‐Catalyzed Selective Hydroamination of Aliphatic Alkenes with Hydrazides

Asian Journal of Organic Chemistry (2021)

Lanlan Xia Yundan Wu Cong Lin Fei Gao Liang Shen

Abstract The first facile and efficient palladium‐catalyzed selective hydroamination of aliphatic alkenes with hydrazides as nitrogen‐based reaction partners has been described. This method provides a divergent and regioselective access to a variety of γ‐ and δ‐hydrazide substituted amide derivatives. The 8‐aminoquinolyl directing group could be readily removed to afford the corresponding γ‐ and δ‐hydrazide substituted carboxylic acid derivatives that are commonly seen in drug molecules and other bioactive compounds.

Hydroamination

Amide

10.1002/ajoc.202100742

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Citations (5)

ChemInform Abstract: Nickel‐Catalyzed Direct Thioetherification of β‐C(sp³)—H Bonds of Aliphatic Amides.

ChemInform (2015)

Cong Lin Wenlong Yu Jinzhong Yao Bingjie Wang Zhanxiang Liu

Abstract A simple procedure is elaborated for the nickel‐catalyzed aminoquinolinyl‐assisted thioetherification of propioamides (I) and (VI).

10.1002/chin.201529117

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Citations (0)

Synthesis of 2,3-dihydro-1H-indazoles by Rh(iii)-catalyzed C–H cleavage of arylhydrazines

Organic & Biomolecular Chemistry (2014)

Jinzhong Yao Ruokun Feng Cong Lin Zhanxiang Liu Yuhong Zhang

A rhodium-catalyzed efficient method for the synthesis of 2,3-dihydro-1H-indazoles is described. The reaction of arylhydrazines with olefins results in the corresponding 2,3-dihydro 1H-indazoles with exclusive regioselectivity via C–H bond activation. The utility of the methodology is illustrated by a rapid synthesis of 1H-indazoles under mild reaction conditions in half an hour.

Cleavage (geology)

Bond cleavage

Reaction conditions

10.1039/c4ob00921e

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Citations (19)

Pd(II)‐Catalyzed Selective Amination of Inert γ‐C(sp³)−O Bonds of Aliphatic Amides with Hydrazines

Asian Journal of Organic Chemistry (2022)

Sai Chen Cong Lin Yiqing Xu Xiuhong Liu Liang Shen

Abstract The first palladium‐catalyzed selective amination of inert methyl and methylene γ‐C(sp 3 )−O bonds of aliphatic amides with hydrazines by using the strategy of 8‐aminoquinoline‐directed C(sp 3 )−H activation/β‐O elimination/hydrofunctionalization is reported. This method features a broad scope of hydrazines, affording an efficient and simple method for the synthesis of corresponding γ‐hydrazine substituted carboxylic acid derivatives that are commonly seen in drug molecules and other bioactive compounds.

Hydrazine (antidepressant)

Inert

Methylene

10.1002/ajoc.202100765

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Citations (1)

ChemInform Abstract: Cobalt-Catalyzed Cyclization of Aliphatic Amides and Terminal Alkynes with Silver-Cocatalyst.

ChemInform (2016)

Jitan Zhang Hui Chen Cong Lin Zhanxiang Liu Chen Wang

Abstract The reaction is successfully extended to aromatic amides to yield various isoindolinones.

10.1002/chin.201611134

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Citations (0)

Nickel‐Catalyzedortho‐Acyloxylation of Benzamides and Acrylamides with Carboxylic Acids

ChemistrySelect (2020)

Jingyi Lin Zhao Guo Cong Lin Fei Gao Liang Shen

Abstract The nickel‐catalyzed ortho ‐acyloxylation of C(sp 2 )‐H bonds of benzamides and acrylamides assisted by8‐aminoquinolyl auxiliary has been realized for the first time. A wide range of carboxylic acids were compatible in this protocol to provide diverse carboxylic esters in moderate to excellent yields.

10.1002/slct.201904651

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Citations (4)