Chunyi Liu

Soochow University

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Zhengping Chen

Xuzhou Medical College

Zuoxiang Wang

Chinese Academy of Medical Sciences & Peking Union Medical College

Feng Liu

Nanjing University of Posts and Telecommunications

Xiangdong Zhou

Dalian Medical University

Richard E. Russo

Lawrence Berkeley National Laboratory

Jong H. Yoo

Applied Spectra (United States)

Victor P. Кolosov

Far Eastern Scientific Centre of Physiology and Pathology of Respiration Russian Academy of Medical Sciences

Xianglei Mao

Lawrence Berkeley National Laboratory

An-Yu Zhou

Southeast University

Juliy M. Perelman

Far Eastern Scientific Centre of Physiology and Pathology of Respiration Russian Academy of Medical Sciences

Cooperative Institutions

Chinese Academy of Sciences

Soochow University

Chang Gung University

Peking University

Kaohsiung Chang Gung Memorial Hospital

Capital Medical University

Tianjin Medical University

Chinese Academy of Medical Sciences & Peking Union Medical College

Sun Yat-sen University

Zhejiang University

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Dynamic Fluctuations of Metastatic Pulmonary Lesions

American Journal of Respiratory and Critical Care Medicine (2024)

Weijie Dong Yan You Chunyi Liu Qing Ma Dan Wang

"Dynamic Fluctuations of Metastatic Pulmonary Lesions." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.

Pulmonary medicine

10.1164/rccm.202307-1135im

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Regulation of endothelial ferroptosis by SESN1 in atherosclerosis and its related mechanism

Aging (2023)

Feng Gao Bin Zhang Zhanfa Sun Yuan Gao Chunyi Liu

Background: Atherosclerosis (AS) is a disease characterized by the disorder of lipid metabolism and the formation of atherosclerotic plaques in the arterial wall, leading to arterial stenosis. Sestrins 1 (SESN1) plays an important regulatory role in AS, but the specific regulatory mechanism is still unclear. Methods: ApoEâ/â mouse models of AS were constructed. After overexpressing SESN1, oil red O staining was used to detect the degree of aortic plaque. HE staining detected the endothelial damage of the surrounding tissues. ELISA was used to detect the levels of vascular inflammation and oxidative stress. The iron metabolism in vascular tissues was detected by immunofluorescence. The expressions of SESN1 and ferroptosis-related proteins were detected by western blot. In the oxidized low-density lipoprotein (ox-LDL)-induced injury model in human umbilical vein endothelial cells (HUVECs), CCK8, ELISA, immunofluorescence and western blot were respectively used to detect cell viability, inflammatory response, oxidative stress and ferroptosis. The regulatory mechanism of SESN1 on endothelial ferroptosis in AS was further explored following the addition of P21 inhibitor UC2288. Results: Overexpression of SESN1 could inhibit the extent of the plaque and reduce the endothelial injury of plaque tissues in AS mice. In both mouse and cell models of AS, SESN1 overexpression inhibited inflammatory response, oxidative stress response, and endothelial ferroptosis. The inhibitory effect of SESN1 on endothelial ferroptosis might be achieved through activation of P21. Conclusion: SESN1 overexpression plays an inhibitory role in vascular endothelial ferroptosis through the activation of P21 in AS.

Oil Red O

Endothelial Dysfunction

Immunofluorescence

10.18632/aging.204777

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Vitamin D nutritional status in early pregnancy and its relationship with periconceptional multiple micronutrients supplementation.

PubMed (2024)

Chunjing Wang Li Zhao Yin-Xiao Bai Wenying Meng Chunyi Liu

To assess the vitamin D nutritional status (VDN) of pregnant women in early pregnancy and investigate the effects of periconceptional supplementation with multiple micronutrients (MMs) on this status.

Micronutrient deficiency

10.6133/apjcn.202403_33(1).0006

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CCDC 717967: Experimental Crystal Structure Determination

The Cambridge Structural Database (2009)

Zuoxiang Wang Chunyi Liu Xiaoming Zhang Xiaoning Gong

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/ccs3376

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A hybrid model combining wavelet transform and recursive feature elimination for running state evaluation of heat-resistant steel using laser-induced breakdown spectroscopy

The Analyst (2019)

Jianwei Huang Meirong Dong Shengzi Lu Yishan Yu Chunyi Liu

Laser-induced breakdown spectroscopy is applied to evaluate the running state of steel by the hybrid model combining wavelet transform and recursive feature elimination.

Laser-induced breakdown spectroscopy

Feature (linguistics)

10.1039/c9an00370c

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Citations (20)

Evolution of LIBS technology to mobile instrumentation for expediting firearm-related investigations at the laboratory and the crime scene

Spectrochimica Acta Part B Atomic Spectroscopy (2023)

Courtney Vander Pyl Korina Menking‐Hoggatt Luis E. Arroyo‐Mora Jhanis J. González Chunyi Liu

10.1016/j.sab.2023.106741

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Citations (10)

Glass particles produced by laser ablation for ICP-MS measurements

Lawrence Berkeley National Laboratory (2008)

Jhanis J. González Chunyi Liu Sy-Bor Wen Xianglei Mao Richard E. Russo

Glass particles produced by laser ablation for ICP-MS measurements Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA *Corresponding author. Tel.: +1-510-486-4258; fax: +1-510-483-7303. rerusso@lbl.gov Jhanis J. Gonzalez, Chunyi Liu, Sy-Bor Wen, Xianglei Mao and Richard E. Russo Abstract Pulsed laser ablation (266nm) was used to generate glass particles from two sets of standard reference materials using femtosecond (150fs) and nanosecond (4ns) laser pulses with identical fluences of 50 J cm -2 . Scanning electron microscopy (SEM) images of the collected particles revealed that there are more and larger agglomerations of particles produced by nanosecond laser ablation. In contrast to the earlier findings for metal alloy samples, no correlation between the concentration of major elements and the median particle size was found. When the current data on glass were compared with the metal alloy data, there were clear differences in terms of particle size, crater depth, heat affected zone, and ICP-MS response. For example, glass particles were larger than metal alloy particles, the craters in glass were less deep than craters in metal alloys, and damage to the sample was less pronounced in glass compared to metal alloys samples. The femtosecond laser generated more intense ICP-MS signals compared to nanosecond laser ablation for both types of samples, although glass sample behavior was more similar between ns and fs-laser ablation than for metals alloys. Introduction Laser ablation processes depend on many parameters which can be grouped by the source. For example, parameters associated to the laser (wavelength, energy, pulse length, spot size, etc.), the environment surrounding the sample (cell design, gas

Laser Ablation

Nanosecond

Particle (ecology)

Source

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Citations (1)

Magnetic Resonance-Electrical Properties Tomography by Directly Solving Maxwell’s Curl Equations

Applied Sciences (2020)

Jieru Chi Lei Guo Aurélien Destruel Yaohui Wang Chunyi Liu

Magnetic Resonance-Electrical Properties Tomography (MR-EPT) is a method to reconstruct the electrical properties (EPs) of bio-tissues from the measured radiofrequency (RF) field in Magnetic Resonance Imaging (MRI). Current MR-EPT approaches reconstruct the EP profile by solving a second-order partial differential wave equation problem, which is sensitive to noise and can induce large reconstruction artefacts near tissue boundaries and areas with inaccurate field measurements. In this paper, a novel MR-EPT approach is proposed, which is based on a direct solution to Maxwell’s curl equations. The distribution of EPs is calculated by iteratively fitting the RF field calculated by the finite-difference-time-domain (FDTD) technique to the measured values. To solve the time-consuming problem of the iterative fitting, a graphics processing unit (GPU) is used to accelerate the FDTD technique to process the field calculation kernel. The new EPT method was evaluated by investigating a numerical head phantom, and it was found that EP values can be accurately calculated and were relatively insensitive to simulated RF field errors. The feasibility of the proposed method was further validated using phantom-based experimental data collected from a 9.4 Tesla (T) Magnetic Resonance Imaging (MRI) system. The results also indicated that more accurate EP values could be reconstructed from the new method compared with conventional methods. Moreover, even in the absence of phase information of the RF field, the proposed approach is still capable of offering robust EPT solutions, thus having improved practicality for potential clinical applications.

Curl (programming language)

Magnetostatics

Graphics processing unit

10.3390/app10093318

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Citations (2)

The relationship between extraintestinal rotavirus infections and serum mannose-binding protein levels

Zhongguo xiaoer jijiu yixue (2010)

Chunyi Liu Ping Jin Shijun Wang Kan Zhang XU Jin-ji

Objective To explore the relationship between extraintestinal rotavirus infections and serum MBP levels. Methods Serum MBP levels were measured by double-antibody sandwich enzyme-linked immunosorbent assays (ELISA) in children including extraintestinal rotavirus infections (n = 76) and common rotavirus enteritis ( n = 63 ) during the acute and convalescence phases. A group of healthy children ( n =50) were recruited as control. Results MBP levels were significantly lower in patients with extraintestinal rotavirus infections( 176.35 ± 113.12 ) μg/L in acute phases than those in patients with common rotavirus enteritis (392. 27 ± 128.96) μg/L and healthy control group(676. 25 ± 248. 63) μg/L, and the difference was significant (P ＜0. 001 ). The serum MBP levels in convalescence phases in the group of extraintestinal rotavirus infections( 358.63 ± 106. 54 ) μg/L was lower than those in the group of common rotavirus enteritis (558. 49 ± 173. 24 ) μg/L and the healthy controls, and their difference was significant ( P ＜ 0. 001 ). The MBP levels in the acute phases among pneumonia group, hepatic lesion group, cardiac damage group and central nervous system damage group caused by rotavirus infection were ( 198.24 ± 126.47) μg/L, ( 169.34 ±124. 38) μg/L,( 184. 62 ± 123.64) μg/L, ( 180. 74 ± 126. 86) μg/L, respectively. The difference among those groups was not significant ( P ＞ 0. 05 ). Conclusion Patients with extraintestinal rotavirus infections showed significantly lower MBP levels during acute and convalescence phases than patients with common rotavirus enteritis. But MBP levels showed no significant differences among those groups of patients with different extraintestinal organ damage caused by rotavirus infection. Lower MBP levels may be associated with the increased susceptibility to extraintestinal rotavirus infections. Key words: Rotavirus ; Extraintestinal infection ; Enteritis ; Mannan-binding protein

Convalescence

10.3760/cma.j.issn.1673-4912.2010.05.011

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Gene expression profiling of Rhododendron pulchrum leaves under drought stress

Tree Genetics & Genomes (2020)

Hua Wang Keyuan Mu Chunyi Liu Yaling Guo Xinyi Deng

Drought Tolerance

Drought stress

Plant hormone

10.1007/s11295-020-01450-2

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Citations (3)