Xiaoyan Xia

Wuhan University of Technology

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Quanyao Zhu

Wuhan University of Technology

Mingrui Gao

Wuhan University of Technology

Wei Wei

Donghua University

Shuokun Sun

Harbin Institute of Technology

Shichuang Cui

Wuhan University of Technology

Wenzheng Ju

Nanjing University of Chinese Medicine

Tan Heng-shan

Nanjing General Hospital of Nanjing Military Command

Xiong Ning-ning

Nanjing University

Fei Wang

Xi'an Jiaotong University

Boris Nemzer

University of Illinois Urbana-Champaign

Cooperative Institutions

Chinese Academy of Sciences

Shanghai Institute of Materia Medica

Wuhan University of Technology

Sichuan University

University of Chinese Academy of Sciences

Chinese Academy of Medical Sciences & Peking Union Medical College

Tsinghua University

Nanjing University of Chinese Medicine

Affiliated Hospital of Youjiang Medical University for Nationalities

Zhejiang University

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Computer modelling and design of form structures

Xiaoyan Xia

10.14264/43fca3c

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The origin and development of Chinese ceramic saggers

Advances in Archaeomaterials (2025)

Junming Wu Chao Lei Yanxia Jiang Renliang Shan Jinxia Hai

10.1016/j.aia.2024.100028

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Effects of prescription reviews in the promotion of continuous improvement of rational drug use.

Zhongguo yiyuan yongyao pingjia yu fenxi (2015)

Tang Zhili Jie Tang Li Wang Linlin Guo Xiaoyan Xia

Promotion (chess)

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Chromatographic Methods for Coffee Analysis: A Review

Journal of Food Research (2017)

Alexander Yashin Yakov I. Yashin Xiaoyan Xia Boris Nemzer

Coffee has been one of the most commercialized food products and most widely researched beverage in the world for decades. It is considered a functional food, primarily due to its high content of compounds that exert antioxidant and other beneficial biological properties. This review summarized the data from analysis of coffee components, both volatile constituents and non-volatile high-molecular weight compounds performed by various chromatographic methods. A list of compounds identified by gas chromatography with mass spectrometry which define the aroma of coffee is provided. Publications on the measurement of methylxanthines (caffeine, theobromine, and theophylline), chlorogenic acids, diterpenes, sugars, amino acids, gamma-aminobutyric acid, dibasic acids, anions, and other compounds by HPLC and UHPLC-MS are reviewed. An overview of publications on the determination of organic contamination in coffee (PAHs, acrylamides, mycotoxins, etc.) and ways to reduce contamination through production technology and brewing methods are presented. Finally, an overview of the literature on authentication assessment for different grades of coffee grown in different regions is provided.

Theobromine

10.5539/jfr.v6n4p60

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Determination of rimantadine in rat plasma by liquid chromatography/electrospray mass spectrometry and its application in a pharmacokinetic study

Journal of Chromatography B (2008)

Meijuan Xu Wenzheng Ju Xiaoyan Xia Tan Heng-shan Min Chen

Rimantadine

Protein precipitation

Amantadine

10.1016/j.jchromb.2008.01.053

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Effect of liquid fermentation on bread fortified with Lycium ruthenicum: A quality attribute and in vitro digestibility study

Food Chemistry (2019)

Hua Wang Xiaoyan Xia Hongzhu Yu Xiaohong Zhao Xuexiu Zhong

10.1016/j.foodchem.2019.125131

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Composition analysis of Compound Shenhua Tablet, a seven-herb Chinese medicine for IgA nephropathy: evaluation of analyte-capacity of the assays

Chinese Journal of Natural Medicines (2024)

Haiyan ZHANG Qiuyue WANG Jianan Wang Zhang Si-chao Weiwei Jia

Chlorogenic Acid

Quinic acid

Ursolic acid

Paeoniflorin

10.1016/s1875-5364(24)60553-4

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Citations (4)

[Simultaneous determination of baicalin and chlorogenic acid in human plasma by UPLC-MS/MS].

PubMed (2007)

Wenzheng Ju Fang Liu Ting Wu Xiaoyan Xia Tan Heng-shan

To develop and validate an ultra performance liquid chromatography tandem mass spectrometric (UPLC-MS/MS) method for the simultaneous quantification of baicalin and chlorogenic acid in human plasma after iv infusion of Yinhuang injection, the analytes were isolated from plasma by protein precipitation with methanol. Then they were chromatographied on an Acquity UPLC BEH C18 column (50 mm x 2.1 mm ID, 1.7 microm) at 40 degrees C. The mobile phase A consisted of water and 0.1% formic acid. The mobile phase B consisted of methanol and 0.1% formic acid. The analytes were eluted from the column with a linear gradient from 5% B to 80% B in 5 min, then hold for 0.5 min before returning to initial condition. The flow rate was 0.35 mL x min(-1). A tandem mass spectrometer equipped with electrospray ionization source was used as detector. Multiple reaction monitoring (MRM) using the precursor to product ion pairs of m/z 447-->271 (for baicalin), m/z 353-->191 (for chlorogenic acid) and m/z 287-->287 (for internal standard) were used to quantification. The linear concentration ranges of the calibration curves for baicalin and chlorogenic acid ranged from 9.6 to 1540 ng x mL(-1) and from 7.5 to 1200 ng x mL(-1), respectively. The intra- and inter-day relative standard deviation (RSD) across three validations run over the entire concentration range was less than 10.2% for both baicalin and chlorogenic acid. After iv infusion of Yinhuang injection to the volunteers, the concentration-time curves of baicalin and chlorogenic acid fitted the two-compartment and three-compartment model. T(1/2)alpha were (4.47 +/- 0.89) and (7.65 +/- 4.42) min, T(1/2)beta were (46.22 +/- 10.03) and (34.40 +/- 19.16) min, respectively. The method was proved to be highly sensitive, selective, and suitable for pharmacokinetic investigations of both baicalin and chlorogenic acid.

Chlorogenic Acid

Baicalin

Protein precipitation

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Computer Cutting Pattern Generation of Membrane Structures

International Journal of Space Structures (2000)

Xiaoyan Xia J.L. Meek

This paper sets out a simple design procedure for generating the cutting patterns of a membrane surface which can then be used for a variety of purposes, including fabric of tension surface. It does this by pre-defining the requirements of the cutting pattern which is set out by the designer on an initially flat surface. A cable net is used for the approximating surface and the cables approximate the warp and weft directions of the fabric (see our previous paper on shape generation). The present work designs the procedure and gives examples of results of the shape finding of a surface with a number of different cutting patterns. An example of a compression membrane surface is also given.

Tension (geology)

10.1260/0266351001495008

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Dynamic and Economic Analysis on the Application of Hypoglucemic Agents

Journal of Military Surgeon in Southwest China (2005)

Xiaoyan Xia

Objective To study the application of hypoglucemic agents through the clinical prescriptions in the central hospital of a city so as to provide information of clinical drug application.Methods Dynamic retrospective analysis was made to the application of hypoglucemic agents in 2002,2003 and 2004 in the hospital through the computer net system.Results The yearly average increase rate of the sum for hypoglucemic agents was 55.98%;the imported hypoglucemic agents played the main role in clinical application,but the sum for insulin injection increased yearly obviously;sulfonylureas and biguanides were the main oral hypoglucemic agents.Conclusions The DUI of hypoglucemic agents are ≤1,which shows that the application of hypoglucemic agents in the hospital is proper;the new hypoglucemic agents are playing a greater role in clinical.

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