A. R. L. P. Ribeiro

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Henrique Almeida

Instituto Butantan

Liliana Matos

Instituto de Biologia Molecular e Celular

Cláudia Freitas

Hospital de Santo António

Christine Costa

Centro Hospitalar de Vila Nova de Gaia

J. L. Silva Carvalho

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

Rejane Andréa Ramalho

Universidade Federal do Rio de Janeiro

Liliana Leite

Polytechnic Institute of Porto

Elisabete Silva

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

J Carvalho

Sligo University Hospital

Alexandra Gouveia

Universidade do Porto

Cooperative Institutions

Universidade do Porto

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

Hospital de São João

Instituto de Biologia Molecular e Celular

CUF Porto Hospital

Hospital de Santa Maria

Polytechnic Institute of Porto

Hospital das Clínicas da Universidade Federal de Minas Gerais

Universidade Estadual de Campinas (UNICAMP)

Hospital da Luz

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Intrahepatic distribution of vitamin A in humans and rats.

PubMed (1988)

H Flores Rejane Andréa Ramalho A. R. L. P. Ribeiro

Liver vitamin A was determined in 10 different regions of the liver from 13 rats and 17 human individuals deceased of various causes. Linear regression analysis and comparison of the values obtained from the different anatomical regions showed that, despite a high degree of heterogeneity in distribution and lack of a consistent pattern, samples from any of the sites analyzed ensure representativeness of the whole liver concentration, taken as the average of the values from the 10 samples of each liver. This means that properly trained personnel, but not necessarily specialized, could draw the liver samples, thus significantly reducing the cost of surveys of vitamin A status based on liver reserves of the vitamin determined at autopsy.

Human liver

Source

Cite

Citations (10)

Journal of Assisted Reproduction and Genetics (2017)

A. R. L. P. Ribeiro Cláudia Freitas Liliana Matos Alexandra Gouveia Filipa Gomes

Activin receptor

BMPR2

Follistatin

10.1007/s10815-017-0930-6

Cite

Citations (13)

HP-07-007 Unveiling the Role of Vasculogenesis in Diabetic Erectile Dysfunction using a Bone Marrow Transplantation Model: Preliminary Results

The Journal of Sexual Medicine (2016)

Christine Costa Ângela Castela Pedro Gomes A. R. L. P. Ribeiro Rui M. Gil da Costa

Vasculogenesis

Bone marrow transplant

10.1016/j.jsxm.2016.03.146

Cite

Citations (0)

Follicular Fluid redox involvement for ovarian follicle growth

Journal of Ovarian Research (2017)

Cláudia Freitas Ana Catarina Neto Liliana Matos Elisabete Silva A. R. L. P. Ribeiro

As the human ovarian follicle enlarges in the course of a regular cycle or following controlled ovarian stimulation, the changes in its structure reveal the oocyte environment composed of cumulus oophorus cells and the follicular fluid (FF). In contrast to the dynamic nature of cells, the fluid compartment appears as a reservoir rich in biomolecules. In some aspects, it is similar to the plasma, but it also exhibits differences that likely relate to its specific localization around the oocyte. The chemical composition indicates that the follicular fluid is able to detect and buffer excessive amounts of reactive oxygen species, employing a variety of antioxidants, some of them components of the intracellular milieu. An important part is played by albumin through specific cysteine residues. But the fluid contains other molecules whose cysteine residues may be involved in sensing and buffering the local oxidative conditions. How these molecules are recruited and regulated to intervene such process is unknown but it is a critical issue in reproduction. In fact, important proteins in the FF, that regulate follicle growth and oocyte quality, exhibit cysteine residues at specific points, whose untoward oxidation would result in functional loss. Therefore, preservation of controlled oxidative conditions in the FF is a requirement for the fine-tuned oocyte maturation process. In contrast, its disturbance enhances the susceptibility to the establishment of reproductive disorders that would require the intervention of reproductive medicine technology.

Follicular fluid

10.1186/s13048-017-0342-3

Cite

Citations (65)