Xiyang Zhang

Air Force Medical University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Yuping Wu

Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)

Dongbo Jiang

Air Force Medical University

Hongqiang Yang

Chinese Academy of Sciences

Fei Tan

Xiangtan University

Ri-Qing Yu

The University of Texas at Tyler

Qi Shi

North China Electric Power University

Kun Yang

Tang Du Hospital

Xian Sun

Kanazawa University

Shuya Yang

Air Force Medical University

Yuanjie Sun

Air Force Medical University

Cooperative Institutions

Air Force Medical University

Chinese Academy of Sciences

Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)

University of Chinese Academy of Sciences

Sun Yat-sen University

Sichuan University

South China Sea Institute Of Oceanology

Institute of Oceanology

Chinese Academy of Medical Sciences & Peking Union Medical College

University of Science and Technology of China

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Fabrication and performance examination on explosively welded ODS-Cu / 316 L clad plate for CFETR divertor heat sink

Fusion Engineering and Design (2022)

Nanyu Mou Qing Zhuang Xiyang Zhang Le Han Beiyan Jiang

Explosion welding

Cladding (metalworking)

10.1016/j.fusengdes.2022.113157

Cite

Citations (2)

In Silico Analyses, Experimental Verification and Application in DNA Vaccines of Ebolavirus GP-Derived pan-MHC-II-Restricted Epitopes

Vaccines (2023)

Junqi Zhang Baozeng Sun Wenyang Shen Zhen-Jie Wang Yang Liu

(1) Background and Purpose: Ebola virus (EBOV) is the causative agent of Ebola virus disease (EVD), which causes extremely high mortality and widespread epidemics. The only glycoprotein (GP) on the surface of EBOV particles is the key to mediating viral invasion into host cells. DNA vaccines for EBOV are in development, but their effectiveness is unclear. The lack of immune characteristics resides in antigenic MHC class II reactivity. (2) Methods: We selected MHC-II molecules from four human leukocyte antigen II (HLA-II) superfamilies with 98% population coverage and eight mouse H2-I alleles. IEDB, NetMHCIIpan, SYFPEITHI, and Rankpep were used to screen MHC-II-restricted epitopes with high affinity for EBOV GP. Further immunogenicity and conservation analyses were performed using VaxiJen and BLASTp, respectively. EpiDock was used to simulate molecular docking. Cluster analysis and binding affinity analysis of EBOV GP epitopes and selected MHC-II molecules were performed using data from NetMHCIIpan. The selective GP epitopes were verified by the enzyme-linked immunospot (ELISpot) assay using splenocytes of BALB/c (H2d), C3H, and C57 mice after DNA vaccine pVAX-GP

ELISPOT

Ebolavirus

10.3390/vaccines11101620

Cite

Citations (4)

Metabolic and metatranscriptional characteristics of corals bleaching induced by the most severe marine heatwaves in the South China Sea

The Science of The Total Environment (2022)

Fulin Sun Hongqiang Yang Xiyang Zhang Qi Shi

KEGG

Metabolome

Metabolic pathway

Coral bleaching

Anthozoa

10.1016/j.scitotenv.2022.160019

Cite

Citations (11)

Increased human occupation and agricultural development accelerates the population contraction of an estuarine delphinid

Scientific Reports (2016)

Wenzhi Lin Leszek Karczmarski Jia Xia Xiyang Zhang Xinjian Yu

Over the past few thousand years, human development and population expansion in southern China have led to local extirpation and population contraction of many terrestrial animals. At what extent this early human-induced environmental change has also affected coastal marine species remains poorly known. We investigated the demographic history of the Indo-Pacific humpback dolphin (Sousa chinensis) in the Pearl River Delta (PRD); an obligatory inshore species known for its susceptibility to anthropogenic impacts in one of China's most developed coastal regions. Although the deltaic evolution of PRD has been influenced by climate since the Holocene, ~74% reduction of the dolphin's effective population size occurred within the last 2000 years, consistent with ~61% habitat contraction during this period. This considerable and recent population contraction may have been due to land use practices and deforestation in the upper/middle Pearl River region, all leading to increasing sedimentation rate in the estuarine area. As anthropogenic impacts within the drainage of Pearl River affected a vast area, coastal dolphins and large terrestrial mammals in southern China may share a similar demographic history, whilst the demographic and biogeographic history of the PRD humpback dolphins may be symptomatic of similar processes that this species may have undergone elsewhere in the region.

Deforestation

10.1038/srep35713

Cite

Citations (21)

Cutting of tungsten plate for fusion device via pre-mixed abrasive water jet

Fusion Engineering and Design (2020)

Yan Wang Li Wang Xiyang Zhang Nanyu Mou Damao Yao

Brittleness

10.1016/j.fusengdes.2020.111790

Cite

Citations (6)

Microplastics in the endangered Indo-Pacific humpback dolphins (Sousa chinensis) from the Pearl River Estuary, China

Environmental Pollution (2020)

Xiyang Zhang Dingyu Luo Ri-Qing Yu Zhenhui Xie Lei He

Indo-Pacific

10.1016/j.envpol.2020.116057

Cite

Citations (40)

Area-specific economic status should be regarded as a vital factor affecting the occurrence, development and outcome of cervical cancer

Scientific Reports (2020)

Zichao Li Haozhi Wu Xiaowei Yi Fangyu Tian Xiyang Zhang

Abstract For patients with cervical cancer, despite the incidence and mortality rates have been declining in recent years, due to its huge population base, cervical cancer has always been a serious public health problem. Our research placed emphasis on the indices greatly associated with overall area-specific social economic status, making up for the defects of traditional research which only pay attention to the situation of some specific disease or patients’ individual social status. A total of 39160 women identified cervical cancer were concluded in our study from the Surveillance, Epidemiology, and End Results (SEER) 18 Program data between 1980 and 2014. With improving the area-specific social economic factors in recent years, the occurrence and prognosis of cervical cancer showed different variation patterns respectively. Some states like California and Georgia for their better economic status and more healthcare investment by local medical institution, population there showed a lower prevalence, incidence, more timely diagnosis, effective treatment, and better prognosis. According to our study, we aimed to give a scientific interpretation on how the area-specific social economic factors affect the disease situation at the macro level and help local medical institution make advisable decisions for controlling cervical cancer.

10.1038/s41598-020-61660-5

Cite

Citations (4)

The aging behavior of biochar and its immobilizing ability to heavy metals in the rhizosphere

Research Square (Research Square) (2022)

Jie Wang Lulu Zhai Xiyang Zhang Yuting Pan Long Zhang

Abstract The application effect of biochar in soil is often affected by environmental factors, but the effect of rhizosphere processes on the properties and functions of biochar remains unclear. The purpose of this study was to explore the effect of the aging process in the rhizosphere on the properties of biochar and the influence of the rhizosphere effect on the performance of biochar for immobilization of heavy metals through different wheat rhizosphere simulation experiments. After aging in the wheat rhizosphere, the physicochemical properties of rice husk biochar (RH BC) and sludge biochar (Sl BC) changed significantly. In general, ash content, specific surface area (SAA), and thermal stability were significantly reduced, while the oxygen (O) content, polarity and surface O-containing functional groups content were significantly increased. The increase of C = O and O = C-OH on the aged biochar surface promotes its adsorption capability for Cd 2+ and Pb 2+ . In addition, the results of the root box experimental showed that the RH BC and Sl BC could effectively reduce the concentration of bioavailable heavy metals in soil, while the rhizosphere effect increases the bioavailability of heavy metals in rhizosphere soil, and then weakens the immobilization effect of RH BC, but has no significant effect on the Sl BC. The increased dissolved organic matter (DOM) content in the rhizosphere soil caused by wheat roots may be an important factor contributing to this phenomenon. Therefore, although the aging process in the rhizosphere may enhance the adsorption performance of biochar for heavy metal, the immobilization effect of biochar for heavy metals in the rhizosphere soil is still at risk of being weakened by the rhizosphere effect.

Husk

Bulk soil

10.21203/rs.3.rs-1648646/v1

Cite

Citations (0)

Geomorphic development of an unvegetated shingle cay on the Ximen Reef in the southern South China Sea

Palaeogeography Palaeoclimatology Palaeoecology (2022)

Shengnan Zhou Qi Shi Hongqiang Yang Lirong Wang Xiyang Zhang

Southern china

10.1016/j.palaeo.2022.111314

Cite

Citations (1)