Youfan Hu

Chengdu University of Traditional Chinese Medicine

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Kaifeng Hu

Chengdu University of Traditional Chinese Medicine

Jiahui Yang

Jiangxi University of Science and Technology

Zhaohui Tang

Chengdu University of Traditional Chinese Medicine

Isidore Mosongo

Chengdu University of Traditional Chinese Medicine

Yanping Li

China Jiliang University

Zhang Liu

Chengdu University of Traditional Chinese Medicine

Suyun Xu

Chengdu University of Traditional Chinese Medicine

Caihong Li

Jilin University

Caihong Bai

Chengdu University of Traditional Chinese Medicine

Qi Zhang

Sun Yat-sen University

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Chengdu University of Traditional Chinese Medicine

Chinese Academy of Sciences

Shanghai University of Traditional Chinese Medicine

Beijing University of Chinese Medicine

Chengdu University

Jilin University

Chinese Academy of Medical Sciences & Peking Union Medical College

Sichuan University

Nanjing Medical University

Shandong University

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Efficacy and safety of repeated transcranial magnetic stimulation combined with escitalopram in the treatment of major depressive disorder: a meta-analysis

Frontiers in Psychiatry (2024)

Zhang Liu Sijia Yu Youfan Hu Ding Wang Shuyu Wang

Objective This study was designed to systematically review the efficacy and safety of repeated transcranial magnetic stimulation (rTMS) combined with escitalopram in treating major depressive disorder (MDD). Methods Databases including PubMed, Embase, Cochrane, Web of Science, CNKI, Wanfang, VIP Journal, and China Biomedical Literature databases were electronically searched for randomized controlled trials of rTMS combined with escitalopram intervention for MDD treatment from the inception of these databases to 27 May 2023. Two reviewers independently screened the studies, extracted the data, and assessed the quality of the included studies. R 4.2.2 was then used for a meta-analysis. Results In total, 19 articles involving 1,032 patients were included. The results of the meta-analysis showed that Hamilton Depression Rating Scale (HAMD) scores were significantly lower in the group receiving rTMS combined with escitalopram (experimental group) than that in the control group [weighted mean difference (WMD) = −5.30, 95% confidence interval (95% CI): −6.44 to −4.17, p < 0.01]. The response rate of the experimental group was significantly higher than that of the control group [odds ratio (OR): 5.48; 95% CI: 3.72 to 8.07; p < 0.01]. No significant difference in the adverse reaction rate was observed between the two groups (OR: 1.04, 95% CI: 0.71 to 1.52, p = 0.82). Conclusion Our findings suggest that rTMS combined with escitalopram can benefit patients with MDD in a safe manner, which may help in guiding clinical practice. Systematic review registration DOI number: 10.37766/inplasy2023.11.0114 , INPLASY2023110114.

Escitalopram

Depression

10.3389/fpsyt.2023.1275839

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Dihydroartemisinin inhibits tumor progress via blocking ROR1-induced STAT3-activation in non-small cell lung cancer

International Immunopharmacology (2024)

Yanping Li Haoyi Sun Caihong Bai Youfan Hu Jingyi Tang

Dihydroartemisinin

ROR1

10.1016/j.intimp.2024.112157

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Metabolomics and Molecular Docking-Directed Anti-Obesity Study of the Ethanol Extract from Gynostemma Pentaphyllum (Thunb.) Makino

Suyun Xu Yalin Deng Caihong Li Youfan Hu Qi Zhang

Download This Paper Open PDF in Browser Add Paper to My Library Share: Permalink Using these links will ensure access to this page indefinitely Copy URL Copy DOI

Gynostemma pentaphyllum

10.2139/ssrn.4798088

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Metabolomics and molecular docking-directed anti-obesity study of the ethanol extract from Gynostemma pentaphyllum (Thunb.) Makino

Journal of Ethnopharmacology (2024)

Suyun Xu Yaling Deng Caihong Li Youfan Hu Qi Zhang

Gynostemma pentaphyllum

10.1016/j.jep.2024.118577

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Integrating 2D NMR-based metabolomics and in vitro assays to explore the potential viability of cultivated Ophiocordyceps sinensis as an alternative to the wild counterpart

Journal of Pharmaceutical and Biomedical Analysis (2024)

Xiu Gu Yanping Li Yang Li Xiaohui Duan Youfan Hu

10.1016/j.jpba.2024.116551

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Efficacy and Safety of Repeated Transcranial Magnetic Stimulation Combined with Escitalopram in the Treatment of Major Depressive Disorder: A Meta-Analysis

Zhang Liu Si-jia Yu Youfan Hu Ding Wang Shuyu Wang

Sensitivity analysis Sensitivity analysis was performed on the HAMD scores and clinical effectiveness results of rTMS combined with escitalopram intervention for MDD.Consequently, one article was excluded, and a meta-analysis was performed on the remaining articles.Country(ies) involved China.

Escitalopram

10.37766/inplasy2023.11.0114

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Citations (1)