This study was performed to investigate anticancer activities and immuno modulatory activities in the several parts of the A. mono and A. okamotoanum. The cytotoxicity of 1 of the water extracts on normal human lung cell(HEL299) was concentration. The secretion of the IL-6 and of human immune B and T cells was increased with all extracts of A. mono and A. okamotoanum. All extracts of. A. mono and A. okamotoanum increased NK cell growth. The results showed that the barks and woods extracts of A. mono and A. okamotoanum had useful biological activities. In addition, bark of A. okamotoanuim showed the highest anticancer and immune activities.
Placental mesenchymal dysplasia is a rare placental vascular anomaly characterized by placento megaly and grapelike vesicles and is recently recognized condition.This resembles partial molar pregnancy by ultrasonography.Placental mesenchymal dysplasia may be associated with adverse complications such as prematurity and intrauterine growth restriction.If placental mesenchymal dysplasia is suspected after antenatal ultrasonography, a serial fetal surveillance should be provided.The placenta should be sent for pathological evaluation after delivery for confirmation of placental mesenchymal dysplasia.A 34 yearold nulliparous woman was referred to Jeju National University Hospital at 24 weeks 3 days of gestation because of preterm vaginal bleeding and multiple cysts in the placenta with previa marginalis by prenatal ultrasonography.At 26 weeks 2 days of gestation, uncontrolled vaginal bleeding and preterm labor ensued, and emergency cesarean section was done.After delivery, histopathologic result of the placenta was placental mesenchymal dysplasia and acute chorioamnionitis.We have described a case complicated with placental mesenchymal dysplasia associated with placenta previa and preterm labor.
Little is known about longitudinal changes of the first twin presentation in twin gestations. This is a retrospective cohort study including 411 women who were admitted consecutively and delivered live-born twins at 36 weeks of gestation or more. Longitudinal assessment of the first twin presentation was conducted during gestation and at birth in all cases. Gestational age at antenatal assessment was divided into two intervals: early-third trimester (28–31 weeks) and mid-third trimester (32–35 weeks). Fetal presentation was categorized as vertex or non-vertex. We analyzed change of fetal presentation between antepartum intervals and birth. First twin presentation at early-third trimester had the same presentation at birth in 87.6% (360/411) of the study population. In this ‘no change’ group, vertex presentation was seen in 95.6% (283/296) and non-vertex was seen in 67.0% (77/115) of cases. In total, 96.1% (395/411) of the study population maintained their presentation between mid-third trimester and birth. Vertex presentation was seen in 98.4% (310/315) and non-vertex was seen in 88.5% (85/96) of cases. When comparing vertex with non-vertex, vertex presentation during third trimester was a more reliable predictor of presentation at birth ( p < .001). The only factor that contributed significantly to spontaneous version of the first twin during mid-third trimester and birth was a lower birth weight of the first twin compared with the second twin. In conclusion, first twin presentation with vertex during third trimester is not likely to change into non-vertex at birth. We concluded that vertex presentation in twin gestations at early- and mid-third trimester is very predictable. In contrast, a non-vertex first twin presentation is relatively unstable.
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