Mayurika Singh

Motilal Nehru Medical College

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Sanjay Singh

All India Institute of Medical Sciences

Aklesh Kumar Maurya

Motilal Nehru Medical College

Anish Kola

Motilal Nehru Medical College

Sabin Sam

Motilal Nehru Medical College

Maha Devan

Motilal Nehru Medical College

Surendra Kumar Gupta

Clinica Sierra Vista

Yajuvendra Kumar Sharma

Sarojini Naidu Medical College

Saurabh Singh

Anil Singh

Academy of Scientific and Innovative Research

Soumitra Manwatkar

Motilal Nehru Medical College

Cooperative Institutions

Motilal Nehru Medical College

All India Institute of Medical Sciences

Banaras Hindu University

Sanjay Gandhi Post Graduate Institute of Medical Sciences

Baylor College of Medicine

Clinica Sierra Vista

Post Graduate Institute of Medical Education and Research

All India Institute of Medical Sciences Raipur

Ambedkar University Delhi

Glangwili General Hospital

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The accuracy of USG and USG guided FNAC axilla in predicting nodal metastasis in a clinically lymph node negative cancer breast patient

International Journal of Research in Medical Sciences (2016)

Vaibhav Shrivastava Sanjay Singh Sanjay Singh Aklesh Kumar Maurya Aklesh Kumar Maurya

Background: Breast malignancies are the second most common cause of cancer-related mortality among women. As the size of the primary breast cancer increases, some cancer cells are shed into cellular spaces and transported via the lymphatic network of the breast to the regional lymph nodes, especially the axillary lymph nodes. Objective of the study was to determine the accuracy of USG and US-FNAC in detecting lymph node metastasis in a clinically lymph node negative CA Breast patient.Methods: This prospective study was conducted on 40 consecutive patients with biopsy proven breast cancer with clinically negative axilla, who had attending the OPD or IPD in our department of surgery, Swaroop Rani Nehru Hospital, Allahabad, during the period of 2014 to 2015. All of these patients were planned to undergo surgery (breast conservation or modified radical mastectomy with axillary clearance).Results: Sensitivity of the study = 97.77%, specificity = 25%, positive predictive value =92.01%, negative predictive value =50%, diagnostic accuracy =90%.Conclusions: Using axillary ultrasound and selective US-FNAC is a rapid, non-morbid method of staging the axilla in newly diagnosed breast cancer patients and should become a routine part of patient care because it can spare many patients particularly those who are undergoing axillary dissection.

Axilla

Modified Radical Mastectomy

Axillary lymph nodes

10.18203/2320-6012.ijrms20164548

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Evaluation of Arthroscopy Versus MRI in Anterior Cruciate Ligament Injuries

International Journal of Contemporary Medicine Surgery and Radiology (2018)

Mayurika Singh Yajuvendra Kumar Sharma

Introduction:The knee is an important weight-bearing joint, capable of performing complex and extensive movements.The study endeavors to determine the role of MRI in diagnosing Anterior cruciate ligament injuries of the knee in comparison to diagnostic arthroscopy in Indian population.Material and Methods: This prospective study was carried out in the Department of Radio diagnosis in collaboration with the Department of ORTHOPAEDICS (sports injury center) TERTIARY Hospital.22 patients presenting with instability and pain of the knee joint and clinical suspicion of ACL injury included in the study.Two patients lost to follow-up hence, were excluded from the survey.These patients underwent MR imaging.Informed and written consent was taken from the patient before they included in the study.All 20 patients were subsequently followed up by arthroscopy/clinically examinations and correlated with findings on MR imaging.Results: Sensitivity of MRI in the diagnosis of ACL injuries is high (90%) however specificity is low.FSE sagittal T2 and coronal PD and STIR sequences were found to be more sensitive to the spectrum of cruciate ligament tears.STIR sequences were useful to evaluate associated bone contusions.Conclusions: MRI has confirmed as the ideal approach for primary diagnosis of ACL lesions.It is noninvasive, fast, can be done on the outpatient basis and is free of complications as compared to diagnostic arthroscopy.But Arthroscopy still remains gold standard for ACL tear diagnosis.

10.21276/ijcmsr.2018.3.4.5

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Incidence of peripheral arterial disease in eastern part of Uttar Pradesh, India in a tertiary hospital and its management

International Surgery Journal (2018)

Sanjay Singh Mayurika Singh Anish Kola

Background: Peripheral artery diseases, group of some pathological conditions affecting limbs are chronic and gradually progressing causing limitation in blood flow. to assess the incidence, related factors and treatment comparison of peripheral arterial diseases in eastern part of Uttar Pradesh.Methods: All the patients come to OPD with suspected peripheral arterial disease are evaluated with proper history taking, investigation and diagnosed the specific pathology and treated accordingly. From these 40 patients conclusions have been made.Results: Majority of the patients were suffered from thromboangitis obliterans (42.55%). Arteriosclerosis obliterans constitute only 12.55% of peripheral arterial disorders.25%were congregation of miscellaneous arterial disorders viz. Rheumatoid arthritis (3 cases), infective gangrene and non-healing ulcers (5 cases) and 2 cases of arteriovenous fistula.Conclusions: Most common peripheral arterial disease is thromboangitis obliterans. Males are commonly affected by peripheral arterial diseases. But incidence of Buerger’s disease increase in females because of increasing habits of smoking and tobacco addiction in any form. Most of patients of T.A.O were villagers while A.S.O, diabetic arteriopathy, vasospastic disease and rheumatoid arthritis commonly affected urban population. Sympathectomies yields good results in early stages of thromboangitis obliterans and vasospastic disease.

Arteriosclerosis obliterans

Gangrene

10.18203/2349-2902.isj20184630

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Correlation of Great Saphenous Vein Diameter in Development of Reflux and Varicosity

International Journal of Contemporary Medicine Surgery and Radiology (2020)

Mayurika Singh Sanjay Singh Anil Singh Maha Devan

Great saphenous vein

10.21276/ijcmsr.2020.5.1.48

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Incidence of phyllodes tumors of breast at a single centre in Allahabad, Uttar Pradesh, India

International Journal of Research in Medical Sciences (2016)

Sanjay Singh Aklesh Kumar Maurya Mayurika Singh

Background: Phyllodes tumor of breast is the rare fibro-epithelial tumor of breast constituting <1% of breast neoplasms. They are locally aggressive tumor and suddenly attain a big size. Fine needle aspiration cytology should have both stromal and epithelial component to make the diagnosis. Wide local excision of 1 to 2 cm margin of normal breast is the treatment of choice for tumour of <10 cm in size and simple mastectomy for tumor more than 10 cm. This study was conducted to evaluate the incidence and outcome after surgery for phyllodes tumor at our centre.Methods: Data of 15 patients at our centre was retrieved retrospectively from January 2011 to April 2016.Results: Out of these 15, 14 were female and 1 was male. 14 of them undergo wide local excision under general anesthesia while in one of the patients simple mastectomy was done. Based on tumor histology they are divided into 3 histotypes i. e. benign, borderline, and malignant. 12 patients were found to be benign, 3 borderline and none malignant. Out of 3 borderline disease patients 1 developed recurrence 8 months later to initial surgery. Wide local excision was done for total of 10 times and every time histopathology revealed borderline phyllodes but last report revealed sarcomatous changes. Patient also developed lung metastases and so was referred to oncology department and review histopathology revealed low grade spindle cell sarcoma. Full radiotherapy and complete course of MAID chemotherapy regimen was given but patient still developed local recurrence and metastasis to lungs. All patients in benign category were doing well and none of them developed recurrences in due course.Conclusions: Phyllodes tumor is an interesting entity for both surgeons as well as pathologists because of its rare occurrence and varied histological features. Rapidly growing nature of this tumor does not necessarily indicate malignant disease. No correlation was found between tumor size and recurrence.

Histopathology

Phyllodes tumor

Wide local excision

10.18203/2320-6012.ijrms20164227

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A comparative study showing effect of local insulin injection on wound vascularization seen in color Doppler imaging in patients with diabetic foot ulcer disease before and after therapy

Asian Journal of Medical Sciences (2022)

Mayurika Singh Saurabh Singh Sanjay Singh Sarthak Uttam

Background: Diabetic foot ulcer disease is one of the most common complications of diabetes, especially in developing nations like India. Management and successful treatment of diabetic ulcers have been under rigorous research and interventions for the past few decades now. This study is an attempt to analyze the effects of a relatively newer treatment modality for diabetic foot ulcers. Aims and Objectives: The primary objective of this study was to determine results after treating patients of diabetic foot ulcers with local insulin injection therapy and compare with the placebo group after 1 week of treatment. Materials and Methods: In this study, 50 patients with diabetic foot ulcer disease were enrolled, of which 25 patients were randomly selected for the intervention group and the rest were kept in a control group. In the intervention group, patients were treated by injecting insulin preparation at the ulcer site whereas in control group, normal saline was used. Wound assessment was done by measuring the ulcer size and by determining the ankle peak systolic velocity (APSV) using color Doppler technique before and after the treatment in both intervention and control groups. Results: Mean ulcer size before the treatment (7.19 cm2) was higher than post-treatment size (3.48 cm2) and the difference was statistically highly significant (P=0.00) while there was no significant difference in ulcer size post-treatment by insulin or non-insulin (normal saline) group (P=0.274). Mean APSV before the treatment (30.75 cm/s) was lower than post-treatment velocity (43.50 cm/s) and the difference was statistically highly significant (P=0.00) while there was no significant difference in APSV post-treatment by insulin or non-insulin (normal saline) group (P=0.061). Conclusion: It meant that insulin and normal saline were equally effective in reducing ulcer size and improving APSV without being superior to one another.

Diabetic foot ulcer

Conventional treatment

10.3126/ajms.v13i12.44757

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Outcome Following Ultrasound Guided Foam Sclerotherapy Treatment for Varicose Veins in a Tertiary Care Centre

International Journal of Contemporary Medicine Surgery and Radiology (2018)

Mayurika Singh Anish Kola Ila Katyayan Soumitra Manwatkar

Tertiary care

10.21276/ijcmsr.2018.3.4.19

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