Wenshuo Tian

The First Affiliated Hospital, Sun Yat-sen University

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Manxia Lin

Sun Yat-sen University

Xiaoyan Xie

Sun Yat-sen University

Baoxian Liu

Beijing Municipal Ecological and Environmental Monitoring Center

Ming Xu

Sun Yat-sen University

Guangliang Huang

Sun Yat-sen University

Wei Wang

Peking University

Luyao Zhou

The First Affiliated Hospital, Sun Yat-sen University

Su Liya

Jingdong (China)

Ming Kuang

The First Affiliated Hospital, Sun Yat-sen University

Bowen Zhuang

The First Affiliated Hospital, Sun Yat-sen University

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Sun Yat-sen University

The First Affiliated Hospital, Sun Yat-sen University

Ultrasonic Technologies (United States)

Harbin Medical University

Shanghai Jiao Tong University

Peking University

Key Laboratory of Guangdong Province

Fujian Medical University

Fudan University

Chinese PLA General Hospital

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Breast Lesions: Quantitative Diagnosis Using Ultrasound Shear Wave Elastography—A Systematic Review and Meta-Analysis

Ultrasound in Medicine & Biology (2016)

Baoxian Liu Yanling Zheng Guangliang Huang Manxia Lin Quanyuan Shan

Diagnostic odds ratio

Subgroup analysis

10.1016/j.ultrasmedbio.2015.10.024

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Citations (78)

Ultrasound-Guided Percutaneous Radiofrequency Ablation of Liver Metastasis From Ovarian Cancer: A Single-Center Initial Experience

International Journal of Gynecological Cancer (2017)

Baoxian Liu Guangliang Huang Chunlin Jiang Ming Xu Bowen Zhuang

The aim of this study was to evaluate the feasibility, effectiveness, and safety of ultrasound-guided percutaneous radiofrequency ablation (RFA) for the treatment of liver metastasis from ovarian cancer (OC).A retrospective review was performed on 11 patients (mean age, 53.0 ± 10.1 years) with 22 liver metastases (mean diameter, 2.0 ± 0.8 cm) from OC undergone RFA. Radiofrequency ablation was carried out with Starburst XL electrodes (RITA Medical System, Mountain View, CA) or Cool-tip electrodes (Cool-tip Systems; Valleylab, Boulder, CO). The tumor response, time to progression, and survival after RFA were assessed.Complete ablation was achieved for all lesions. The technique effectiveness was 100%. During the follow-up period, local tumor progression was observed in 1 (4.5%) of 22 lesions. The median time to progression was 8.0 months after RFA. Three patients died because of disease progression after 13, 18, and 24 months, respectively. The mean overall survival time after RFA was 53.1 ± 10.0 months, with the 1-, 3-, and 5-year overall survival rates of 100%, 61%, and 61%, respectively. No major complications were encountered.Radiofrequency ablation as an alternative treatment strategy is feasible and effective for selected patients with liver metastasis from OC, providing a high rate of local tumor control.

Tumor progression

Liver Cancer

10.1097/igc.0000000000000939

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Citations (16)

Combined radiofrequency ablation with intrahepatic vascular occlusion using laser ablation in dogs: in vivo experimental studies

Zhonghua chaosheng yingxiangxue zazhi (2015)

Manxia Lin Ming Xu Guangliang Huang Xiaoyan Xie Baoxian Liu

Objective To explore the feasibility and experimental conditions of laser ablation in occluding great liver vessels of dogs and whether the volume of radiofrequency ablation (RFA) could be expanded by combining with intrahepatic vascular occlusion. Methods Ten UK Beagles were divided into two groups randomly.UK Beagles were numbered as D1 to D5 in group 1 and as D6 to D10 in group 2. Laser ablation, with the fiber exposed of 1.0 cm and total power of 1 800 J, was used to block the left or middle hepatic blood vessels of D1~D5 in group 1 firstly. Laser ablation was end when color Doppler imaging showed no blood signal in the selected portal vein and hepatic artery. Contrast enhanced ultrasound (CEUS) was performed to assess the blood supply of the selected lobe of canine liver 30 min after laser ablation.Right after CEUS was performed, single point single ablation was carried out in this lobe using RFA. The same procedure of RFA was performed in the left or middle lobe of D6~D10 in group 2. The volume of radiofrequency ablation was measured using CEUS 6 days after ablation. Results Reduced or no enhancement was seen in the partial or entire liver lobe on CEUS after laser ablation. The average ablation volume was (111.7±70.4)cm3 in D1~D5 and (10.0±2.0)cm3 in D6~D10, respectively, the difference was statistically significant (P=0.032). Conclusions Great liver vessels in dogs could be partially or completely occluded by using laser ablation, causing liver lobe to part or all of ischemia or necrosis, the volume of radiofrequency ablation could be expanded by blocking the blood vessels. Key words: Ultrasonograhpy; Microbubbles; Catheter ablation; Laser therapy; Liver

Laser Ablation

Blood supply

10.3760/cma.j.issn.1004-4477.2015.02.018

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Ultrasound-guided percutaneous transhepatic thrombolysis for treatment of portal vein thrombosis after liver transplantation

中国医师杂志 (2017)

Jia Luo Jianwei Lin Liya Su Manxia Lin Wenzhe Fan

Objective To evaluate the effective and safety of ultrasound-guided percutaneous portal vein guide wire placement adjunct to thrombolytic catheter, which treating portal vein thrombosis after liver transplantation. Methods From Jan 2012 to Dec 2015, a total of 6 patients (5 male, 1 female, average age 50.6 years old, age range 41-65 years old ) with portal vein thrombosis after liver transplantation were retrospectively studied. The diagnosis was confirmed by contrast enhanced ultrasound (CEUS) with hypoechonic and no enhancement in portal vein. With ultrasound-guided a 18-guage guide wire was placed in right branch of portal vein, and a guidewire was placement. After exchanging the catheter, the thrombosis was confirmed again by venography. A thrombolytic catheter was placed and local thrombolysis therapy was performed. Results The guidewires were successfully placed in 6 patients. The thrombolytic catheters were successfully placed in 5 patients (day 2-60 after operation), and failed in 1 patient (9 years after operation). With 5-11 days urokinase injection, the patency of portal vein was found in 5 patients, of which 4 patients was treated by angioplasty and stent placement. With 16-31 months follow-up, the patency of portal vein was maintained. Neither server complication nor related-death was occurred. Conclusions Ultrasound-guided percutaneous portal vein guide wire placement adjuncts thrombolytic catheter is effective and safety for treating portal vein thrombosis after liver transplantation. Key words: Ultrasonography; Portal vein/SU; Hepatic veins/SU; Phlebotomy; Thrombolytic therapy; Venous thromboembolism/CO/SU; Liver transplantation/AE

Portal vein thrombosis

Venography

Portography

10.3760/cma.j.issn.1008-1372.2017.06.007

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Value of intracavitary contrast-enhanced ultrasound via abdomen in fistulas difficult to diagnose before operation

中国医师杂志 (2017)

Yujun Chen Ren Mao Xiaohua Xie Wenshuo Tian Ming Xu

Objective To evaluate the value of intra-cavitary contrast-enhanced ultrasound (IC-CEUS) via abdomen in fistulas difficult to diagnose before operation. Methods Clinical data of 12 patients with preoperative clinical suspicion of Crohn's Disease (CD) complications of fistula were enrolled in the study. Colonoscopy, cystoscope, or CT/MR has not confirmed the diagnosis of intra abdominal fistulas. IC-CEUS were performed by locally-injection of contrast agent in abdominal abscess, observing fistula and the relationship with the adjacent organs in CEUS mode. Diagnostic criteria were surgical findings. Results Fistulas in 10 patients were detected by IC-CEUS, including 7 cases of Ileo-mesenteric fistuls, 2 cases of ileo-vesical fistulas, and 1 case of colo-vesical fistula. The accuracy rate of IC-CEUS in diagnosis of fistulas difficult to diagnose before operation in Crohn's disease was 83.3%(10/12). No severe adverse events occurred during and after IC-CEUS procedure. Conclusions Our preliminary study shows that IC-CEUS is feasible in detecting abdominal fistula with high accuracy. It might be used as the alternative imaging technique for detecting fistulas when CT and MR are insufficient. Key words: Endosonography; Crohn disease/CO/US; Fistula/CO/US; Abdominal cavity/PA/US

Contrast-enhanced ultrasound

10.3760/cma.j.issn.1008-1372.2017.06.003

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【結語】肝イメージングイメージングの硬さ分布を評価するための剪断の臨床的研究【JST・京大機械翻訳】

Zhonghua Chaosheng Yingxiang Xue Zazhi (2016)

Su Liya Wenshuo Tian Manxia Lin Xu Ming Xiaoer Zhang

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Elastography by acoustic radiation force impulse technology for differentiation of benign and malignant breast lesions: a meta-analysis

Journal of Medical Ultrasonics (2015)

Bao‐Xian Liu Yanling Zheng Quanyuan Shan Ying Lu Manxia Lin

Acoustic Radiation Force

10.1007/s10396-015-0658-9

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Citations (24)

Transplant renal artery stenosis: Evaluation with contrast-enhanced ultrasound

European Journal of Radiology (2017)

Fu‐shun Pan Ming Liu Jia Luo Wenshuo Tian Jin-Yu Liang

Contrast-enhanced ultrasound

10.1016/j.ejrad.2017.02.031

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Citations (36)

Shear wave elastography-based ultrasomics: differentiating malignant from benign focal liver lesions

Abdominal Radiology (2020)

Wei Wang Jianchao Zhang Wenshuo Tian Li‐Da Chen Qiao Zheng

10.1007/s00261-020-02614-3

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Citations (17)

Evaluation for real-time elastography versus shear wave elastography on the ablation zone of rabbit liver: a preliminary experimental study

Zhonghua chaosheng yingxiangxue zazhi (2016)

Ming Xu Manxia Lin Bowen Zhuang Liya Su Xiaoju Li

Objective To comparatively evaluate the ablation zone of rabbit liver with real-time elastography (RTE) and shear wave elastography (SWE). Methods A unipolar internal cooled radiofrequency probe was used to form the ablation zone for ten rabbit liver. After the ablation, RTE and SWE were used to measure the value of elastography. Contrast enhanced ultrasound was also used to assess the ablation zone. The value of elastography from these two methods and the scope of ablation zone among the CEUS images, samples and elastography images were compared, respectively. Results RTE and SWE could display the scope of ablation zone just after the ablation. RTE image could get the ratio of the ablation zone and the surrounding liver which was 3.22±0.70. SWE could display the value of elasticity decreased from the center to the edge of ablation zone. The value of elasticity for the center and the rim of ablation zone were (51.1±11.5)kPa and (29.70±3.28)kPa. The area of ablation zone for RTE and SWE were (1.087±0.179)cm2 and (1.058±0.219)cm2. There were no difference in the ablation area among RTE, SWE and the gross specimen (P>0.05). CEUS displayed non-enhancement for ablation zone, but the area of ablation zone was larger than those from gross sample (P<0.05). Conclusions RTE and SWE could confirm the scope of ablation zone. And the SWE provides the guidance for confirming the boundary of ablation zone for the future clinical application. Key words: Shear wave elastography; Real-time elastography; Radiofrequency ablation; Liver

Ablation zone

10.3760/cma.j.issn.1004-4477.2016.11.019

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