Yuying Tian

Xi’an University of Posts and Telecommunications

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Weibo Zhang

China Agricultural University

Guangjun Wang

Chinese Academy of Medical Sciences & Peking Union Medical College

Shuyong Jia

Chinese Academy of Medical Sciences & Peking Union Medical College

Tao Huang

Affiliated Hospital of Guizhou Medical University

Gerhard Litscher

Medical University of Graz

Lu Wang

Qilu Hospital of Shandong University

Yi-hui Xu

Chinese Academy of Medical Sciences & Peking Union Medical College

Rui-Hong Wang

Zhejiang Sci-Tech University

Yindi Yao

Xi’an University of Posts and Telecommunications

Wenting Zhou

Fudan University

Cooperative Institutions

Chinese Academy of Medical Sciences & Peking Union Medical College

Xi’an University of Posts and Telecommunications

China Academy of Chinese Medical Sciences

Chinese Academy of Sciences

Fudan University

Shanghai Jiao Tong University

China Association of Acupuncture-Moxibustion

Capital Medical University

Tongji University

Nanjing Medical University

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Pilot study of blood perfusion coherence along the meridian in forearm

BMC Complementary and Alternative Medicine (2013)

Guangjun Wang Yuying Tian Shuyong Jia Wenting Zhou Weibo Zhang

Abstract Background Many studies have explored the relationship between skin microcirculation and meridian activation. However, few studies have examined blood perfusion coherence along the meridians, and other studies have suggested that the skin vasodilator response relates to age. This study investigated blood perfusion coherence characteristics along the meridian of the forearm in healthy volunteers. Methods A total of 15 young subjects (25.53 ± 2.20) and 15 middle-aged subjects (50.07 ± 3.37) were recruited for this study. Before experiments, each subject was placed in a temperature-controlled room for 60 min. Skin blood perfusion from five points was recorded simultaneously using a full-field laser perfusion imager before and after inflatable occlusion. The five points comprised three points located on the pericardium meridian, and two points from different locations. Coherence analysis between these points was performed at different frequency intervals from 0.0095 to 2 Hz. Results In young subjects, the coherence value was unchanged before and after occlusion, and there was no significant difference in coherence value between meridian-meridian points (M-M) and meridian-parameridian points (M-P). In middle-aged subjects, the coherence value increased significantly in both M-M and M-P at frequency intervals of 0.14-0.4 Hz, 0.4-1.6 Hz, and 1.6-2 Hz. However, there was no significant difference in coherence values between M-M and M-P. Conclusions Inflatable occlusion can increase middle-aged subjects’ blood perfusion coherence value of the forearm. However, there is no specificity in meridian location.

Meridian (astronomy)

10.1186/1472-6882-13-327

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Citations (8)

[Experimental verification of "treating lumbar-back problems by puncturing Weizhong (BL 40)" with blood perfusion imaging technique].

PubMed (2007)

Lingling Wang Weibo Zhang Heng-hui Xie Yuying Tian Yi-hui Xu

To verify the classic saying of "Treating lumbar-back problems by puncturing Weizhong (BL 40)" in acu-moxibustion learning and to explore its underlying mechanism.Forty volunteer sublects were asked to accept twice tests respectively, i.e., acupuncture of Weizhong (BL 40) and Yanglingquan (GB 34), for observing changes of skin blood perfusion (SBP) at the low back part of the body by using a laser Doppler perfusion imager. The whole observed area (lower back) was divided into five sub-areas, left and right areas involving Line-one and Line-two of the Bladder Meridian.In comparison with pre-acupuncture, SBP of both BL40 and GB34 groups increased significantly from 4 minutes' retention of needles on to 12 mm after withdrawing acupuncture needle (P < 0.01), but no significant difference was found between two groups in SBP (P > 0.05). The change rates of SBP at Line-one and Line-two of the Bladder Meridian on the same side of the stimulated Weizhong (BL 40) were significantly higher than those of Yanglingquan (GB 34) (P < 0.05), but no significant changes were found on the opposite side (both Line-one and Line-two) of the Bladder Meridian.Acupuncture of both BL4O and GB34 can increase SBP at the low back of the body (involving the Bladder Meridian) on the same side, but the changing rate of SBP of BL4O is hiaher than that of GB34.

Meridian (astronomy)

Puncturing

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Bilateral Hegu Acupoints Have the Same Effect on the Heart Rate Variability of the Healthy Subjects

Evidence-based Complementary and Alternative Medicine (2014)

Guangjun Wang Yuying Tian Shuyong Jia Wenting Zhou Weibo Zhang

Background. The specificity of acupuncture points (acupoints) is one of the key concepts in traditional acupuncture theory, but the question of whether there is adequate scientific evidence to prove or disprove specificity has been vigorously debated in recent years. Acupoint laterality is an important aspect of acupoint specificity. Data is particularly scarce regarding the laterality of the same channel, namesake acupoint located on opposite sides of the body. Our previous study results suggest that Neiguan acupoint (PC6) has the laterality. The aim of this study was to investigate whether Hegu (LI4) also has laterality from the perspective of heart rate variability. Methods. A total of twenty-eight healthy female volunteers were recruited for this study and were randomly separated into the group I (n = 14) and the group II (n = 14) according to the register order. In the group I, left LI4 was stimulated in the first epoch and the right LI4 was stimulated in the second epoch. In the group II, right LI4 was stimulated in the first epoch and left LI4 was stimulated in the second epoch. Electrocardiogram was recorded and heart rate variability was analyzed. Results. The results show that there were no significant differences of heart rate variablity between the group I and the group II in the time domain and in the frequency domain. Conclusions. Bilateral Hegu acupoints have the same effect on the heart rate variability of the healthy subjects.

Epoch (astronomy)

10.1155/2014/106940

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Citations (13)

Finding a Novel Threadlike Structure on the Intra-abdominal Organ Surface of Small Pigs by Using In Vivo Trypan Blue Staining

Springer eBooks (2011)

Ayati M. Hossein Yuying Tian Tao Huang Yuqing Zhang Yongzhe Che

Trypan blue

10.1007/978-1-4614-0601-3_9

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Citations (6)

Research of coverage optimization strategy based on improved northern goshawk algorithm

IEEE Sensors Journal (2024)

Yindi Yao Xiaoxiao Song Bozhan Zhao Yuying Tian Ying Yang

Optimization algorithm

10.1109/jsen.2024.3419174

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Comparison of Acupuncturing Hegu (LI4) by Metal or Laser Needle on Facial Blood Perfusion Using Laser Speckle Technique

Journal of Acupuncture and Meridian Studies (2011)

Yuying Tian Tao Huang Gerhard Litscher Lu Wang Guangjun Wang

To compare the difference of remote effects of acupuncture between metal needle and laser needle on facial blood perfusion (FBP). Hand acupuncture and laser-needle acupuncture were randomly used on Hegu (LI4) in 20 healthy volunteers. FBP was observed by speckle contrast imager before, during, and after the acupunctures. For hand acupuncture there were gradual increases on the nose and left and right visor areas (p < 0.05 or p < 0.01) during the acupuncture and on an immediate increase (p < 0.01) that remained constant during the acupuncture on the forehead area but no significant increase on mouth area. During laser-needle acupuncture, on the other hand, there was a tendency of increase on the nose, left visor, and right visor areas but these were non significant. Hand acupuncture can influence FBP in remote places connected by meridians.

10.1016/j.jams.2011.09.007

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Change of Blood Perfusion in Hegu Acupoint After Contralateral Hegu Acupoint Was Stimulated

The Journal of Alternative and Complementary Medicine (2012)

Guangjun Wang Yuying Tian Shuyong Jia Huang Tao Weibo Zhang

The objective of this study was to investigate the change of mean blood flux in Hegu acupoint after contralateral Hegu acupoint was stimulated.Healthy volunteers (N=140) were placed in a temperature-controlled room as a resting state for 60 minutes. Then the measurements of skin blood flow were carried out in pre- and postacupuncture stimulation every 30 minutes over a total of 180 minutes using a Moor full-field laser perfusion imager. The change ratio of mean blood flux in Hegu acupoint was used to evaluate the contralateral stimulation effect in different groups.After acupuncture of the right Hegu acupoint (AR), the change ratio of mean blood flux in the left Hegu acupoint was increased significantly compared with the control group 60 minutes after acupuncture stimulation (p<0.01). Then the blood flow in the AR group was sustained at a higher level compared with that of the control group (p<0.05). However, the change ratio of mean blood flux in the right Hegu acupoint increased significantly in the 30 minutes after contralateral acupuncture stimulation (p<0.01). From that point on, the change ratio was sustained at a higher level in the AR group than in the control group until 150 minutes after stimulation (p<0.05).On stimulation of either the left or right side of Hegu acupoint, the change ratio of mean blood flux was increased in the contralateral Hegu acupoint in a period from 30, 60, to 150 minutes after stimulation, respectively.

10.1089/acm.2011.0440

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Citations (20)

Finding Blue Tracks in Gephyrocharax melanocheir Fish Similar to the Locations of Acupuncture Meridians after Injecting Alcian Blue

Journal of Acupuncture and Meridian Studies (2015)

Ze Wang Weibo Zhang Shuyong Jia Yuying Tian Guangjun Wang

This study investigated whether a meridian-like distribution of Alcian blue (AB) existed after it was injected into a fish's body and suggested a new animal model for meridian study. Twenty Gephyrocharax melanocheir fish with translucent bodies were injected with AB at a point near the spinal column or the dorsal fin. Distribution of AB was observed using a digital camera and a stereomicroscope. Three or more obvious blue tracks were found: one along the spinal column, another along the posterior margin of the abdomen extending to the superior margin of the anal fin, and a third along both sides of the dorsal fin. They were similar to the locations of the governor, conceptual vessel, and urinary bladder meridians, respectively, on the human body according to the classic theory of traditional Chinese medicine. A few other blue tracks were also found, which apparently did not correspond to any known meridians. The results show that the tracks of AB share important similarities with the locations of classically described meridians and that they are mainly distributed in the interstitial space around bones and blood vessels and inside muscular interstices. This study may provide a new experimental animal model for exploring acupuncture meridians.

Meridian (astronomy)

Fish fin

Dorsal fin

Spinal column

10.1016/j.jams.2015.08.007

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Citations (9)

Longitudinal directional movement of Alcian blue in Gephyrocharax Melanocheir fish: Revealing interstitial flow and related structure

World Journal of Acupuncture - Moxibustion (2019)

Weibo Zhang Xiaojing Song Ze Wang Guangjun Wang Shuyong Jia

10.1016/j.wjam.2019.05.008

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Citations (4)

Response of Blood Perfusion at ST 36 Acupoint after Drinking Cold Glucose or Saline Injection

Evidence-based Complementary and Alternative Medicine (2017)

Guangjun Wang Shuyong Jia Hongyan Li Ze Wang Yuying Tian

Skin blood flux (SkBF) changes caused by drinking cold water are generally associated with vagal tone and osmotic factors in digestive system. According to acupuncture theory, change of SkBF at ST 36 might reflect the functional changes of digestive system. The aim of this study is to analyze the changes of SkBF after drinking 3°C 0.9% saline or 5% glucose injection by monitor blood flux at bilateral ST 36. The results indicated that, after drinking different cold water, the change ratio of SkBF at right side ST 36 has been different. Because all solutions have the same temperature (3°C) and both saline and glucose solution have the same osmolality, suggesting that the SkBF changes resulting from drinking cold water are not regulated just by the vagal tone and osmolality, there must have been other factors. These results have not been consistent with the frequency domain results of heart rate variability (HRV) analysis. Coherence analysis of blood flux signals at bilateral ST 36 indicated that there have been different coherence-frequency curves among different groups in special frequency bands, which suggested that coherence analysis might provide a potential tool to evaluate different status.

10.1155/2017/4212534

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Citations (312)