An improved automatic measurement setup for measuring inner diameter of outer conductor (IDOC) in coaxial air lines with precision connectors, including N, 7 mm, 3.5 mm, 2.92 mm, 2.4 mm, and 1.85mm, is introduced. The improved setup can accurately measure the straightness and the position of measured cross-section of IDOC. Multi-gauge calibration method and orthogonal regression algorithm are used to achieve measurement uncertainty smaller than 0.3µm. As an example, the measurement results of air lines with precision 2.92 mm and type N connectors are shown.
Allium tenuissimum L. is a widely distributed perennial herbaceous species in temperate and desert steppes. Relative to other wild Allium species, it produces unique sweet flavors, more biomass in arid and cold environments, and has generated greater interest for crop production. Successful crop establishment, however, will depend on rapid and uniform seed germination. Our study aimed to characterize seed germination of A. tenuissimum under various temperature regimes (11, 15, 20, 24 and 28 °C) and water potential levels (0, -0.2, -0.4 and -0.6 MPa), and model germination by hydrotime (HT) and hydrothermal time (HTT) analysis. Final germination percentage (FGP) increased within the range of 11 to 20 °C, yet it declined within the range of 24 to 28 °C and generally decreased as water potential became more negative within each temperature setting. Maximum FGP was observed at 20 °C at all water potential settings and ranged from 55.0 ± 5.3 to 94.8 ± 1.4%. According to HT and HTT models, the base (Tb) and optimum temperatures (To) for seed germination were 7.0 and 20.5 °C, respectively. In addition, base water potential for the fraction of germination within the seed lot (Ψb(g)) shifted to 0 MPa as temperature increased from Tb to ceiling temperature (Tc). For obtaining 50 % seed germination, Ψb(50) and Tc(50) were estimated to be -0.67 MPa and 27.2 °C, respectively. These values for Tb and Ψb(50) suggest seed germination of A. tenuissimum is both cold and drought tolerant and suitable for production in semi-arid regions. Our characterization of the ideal sowing conditions for A. tenuissimum, i.e., 20.5 °C and soil water potential less negative than -0.67 MPa offers information to forecast suitable settings to enhance crop production.
In order to improve the flexibility and portability of astronomical camera software and its driver, a scheme of astronomical camera software system is designed and implemented based on the astronomical software interface standard ASCOM. In this scheme, the camera software is divided into driver layer, logic layer, interface layer and application layer, and the astronomical camera driver development based on ASCOM standard, astronomical observation function module packaging, interface function module packaging and human-computer interaction interface creation are realized in turn. This paper introduces the structural design and working principle of the software scheme, and introduces the implementation methods of the main key units in detail, and finally verifies the feasibility of this scheme through the results of test cases. This paper lays a foundation for the research on the standardized control of astronomical camera terminal and the general architecture of system software.
Infrared and visible light image fusion technology integrates feature information from two different modalities into a fused image to obtain more comprehensive information. However, in low-light scenarios, the illumination degradation of visible light images makes it difficult for existing fusion methods to extract texture detail information from the scene. At this time, relying solely on the target saliency information provided by infrared images is far from sufficient. To address this challenge, this paper proposes a lightweight infrared and visible light image fusion method based on low-light enhancement, named LLE-Fuse. The method is based on the improvement of the MobileOne Block, using the Edge-MobileOne Block embedded with the Sobel operator to perform feature extraction and downsampling on the source images. The intermediate features at different scales obtained are then fused by a cross-modal attention fusion module. In addition, the Contrast Limited Adaptive Histogram Equalization (CLAHE) algorithm is used for image enhancement of both infrared and visible light images, guiding the network model to learn low light enhancement capabilities through enhancement loss. Upon completion of network training, the Edge-MobileOne Block is optimized into a direct connection structure similar to MobileNetV1 through structural reparameterization, effectively reducing computational resource consumption. Finally, after extensive experimental comparisons, our method achieved improvements of 4.6%, 40.5%, 156.9%, 9.2%, and 98.6% in the evaluation metrics Standard Deviation(SD), Visual Information Fidelity(VIF), Entropy(EN), and Spatial Frequency(SF), respectively, compared to the best results of the compared algorithms, while only being 1.5ms/it slower in computation speed than the fastest method.
One of the main causes of lung cancer-related death is brain metastasis (BM). Finding early indicators of BM derived from lung cancer is crucial. Therefore, this study was designed to determine if serum hsa_circ_0072309 may be employed as a potential biomarker for BM induced by non-small-cell lung cancer (NSCLC) and to understand its possible underlying mechanism.Primary lung cancer and healthy neighboring tissues were obtained from all patients, while BM tissues were taken from BM+ patients. Serum specimens were collected from all patients and healthy volunteers. Hsa_circ_001653, miR-100, and ACKR3 RNA expressions were analyzed by quantitative reverse transcription-polymerase chain reaction (qRT-PCR), and atypical chemokine receptor 3 (ACKR3) protein expression by western blotting (WB), immunohistochemistry (IHC), and enzyme-linked immunosorbent assay (ELISA). In order to examine the effect of serum hsa_circ_0072309 and its relevant mechanism on BM development, an NSCLC-associated BM model in mice was established.According to the results, miR-100 expression was down-regulated in primary lung cancer tissues compared to healthy lung tissues in all NSCLC patients, and circ_0072309 and ACKR3 expression were up-regulated. In BM tissues compared with primary lung tumors of BM+ patients, in serum samples from all patients compared to healthy volunteers, and in lung tumors of BM+ patients compared to those from BM- patients. Patients' serum exhibits the same level of hsa_circ_0072309/miR-100/ACKR3 expression as in BM samples. Advanced tumor-node-metastasis (TNM) stage, higher BM, shorter post-operative overall survival (OS), and progression-free survival (PFS) are all substantially associated with increased serum circ_0072309 levels in BM+ patients. In animal models, serum owning hsa_circ_0072309 from BM+ patients facilitates BM formation by regulating the miR-100/ACKR3 pathway.The current preliminary research reveals serum hsa_circ_0072309 as a possible biomarker and target for early diagnosis, prognosis, and therapy of NSCLC-derived BM and suggests a substantial role for the hsa_circ_0072309/miR-100/ACKR3 axis in the formation of BM from NSCLC.
We employ two techniques to measure the intrinsic efficiency of a waveguide adapter used in a U band waveguide power standard. These two methods are based on one-port calibration. The results measured by this two techniques agree within 0.005 for efficiency one.
Arsenic is a widespread naturally contaminant, previous studies, including ours, have highlighted the issue of liver fibrosis induced by arsenic exposure, while the exact mechanisms are not yet fully understood. Recent studies suggested that Mig-6/EGFR signaling pathway appear to play important roles in fibrosis caused by various factors. In this study, we focused on the epigenetic modification combined with the signaling dysregulation to validate the role of Mig-6 in regulating EGFR/ERK signaling in arsenite-exposed human hepatic stellate cells (HSCs). Our results revealed that arsenite exposure induced HSCs activation and extracellular matrix (ECM) deposition. The EGFR/ERK signaling were significantly hyperphosphorylated in arsenite-exposed HSCs, and Mig-6 inactivation was involved in arsenite induced hyperphosphorylation of EGFR and activation of HSCs. Additionally, we further illustrated that hypermethylation of Mig-6 gene promoter region was responsible for the downregulation of Mig-6 induced by arsenite exposure. Moreover, 5-aza-2′-deoxycytidine (a DNA methyltransferase inhibitor) can efficiently rescued hypermethylation of Mig-6 gene, decreased the hyperphosphorylation of EGFR/ERK signaling, then reversed arsenite induced HSCs activation. Taken together, the present study strongly suggests that inactivating of Mig-6 function by hypermethylation of its promoter region activates hyperphosphorylation of EGFR/ERK signaling, is involved in arsenite-induced HSCs activation and ECM deposition.
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