A doubled haploid population, derived from anther culture of F 1 hybrid between a typical indica cv. Zhaiyeqing 8 and a japonica cv. Jingxi 17, has been used in this study. The chalkiness sizes of transverse section, flank section and belly section, were investigated in 127 DH lines with video microscopy and computer image analysis technique. The quantitative trait loci (QTLs) for the size of chalkiness were analysed. A total of nine QTLs were detected in five intervals of three chromosomes, including three QTLs for transverse section, three QTLs for flank section and three QTLs for belly section. The directions of additive effect of QTLs for three sections were identical, and the intervals and peak of LOD on three chromosomes were overlapping, some of them were uniform. The application value of video microscopy and computer image analysis technique in rice chalkiness analysis were discussed.

Doubled haploidy

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Citations (10)

MiR-1249 on Endothelial Extracellular Vesicles Mediates Cigarette Smoke–Induced Pulmonary Hypertension by Inhibiting HDAC10 (Histone Deacetylase 10)-NFκB (Nuclear Factor κB)-CaSR (Calcium-Sensing Receptor) Cascade

Hypertension (2022)

Su Yuan Rubin Tan Mengxiang Sun Linbo Yuan Matthieu Ruiz

Overproduction of endothelial extracellular vesicles (eEVs) is correlated with pulmonary hypertension progression, but the precise mechanism remains largely unclear.MicroRNA-chip and real-time polymerase chain reaction were conducted to screen and validate microRNA profiles in blood plasma eEVs of rats and human with or without cigarette smoking. Pulmonary artery smooth muscle cells were cultured to study signaling pathways. Pulmonary hypertension phenotypes were evaluated in wild-type and calcium-sensing receptor knockout rats to identify the pathophysiological significance of the microRNA pathway.MicroR-1249 was predominant highly expressed in eEVs from plasma of rats exposed to cigarette smoking, and confirmed in eEVs from plasma of human smokers as well as in eEVs from cigarette smoke extract-treated pulmonary artery endothelial cells, but not in cigarette smoke extract-treated pulmonary artery smooth muscle cells. In cultured pulmonary artery smooth muscle cells, microR-1249 downregulated the expression of histone deacetylase 10, which in turn enhanced the acetylated form of NFκB (nuclear factor κB) level and its nuclear translocation leading to increased expression of calcium-sensing receptor. In rats, the repression of microR-1249 in eEVs by microR-1249 inhibitor, histone deacetylase 10 overexpression, or calcium-sensing receptor knockout profoundly inhibited the proliferative capacities and diminished apoptosis-resistance of pulmonary artery smooth muscle cells and pulmonary hypertension development in rats intravenously administrated with eEVs preparation from cigarette smoke extract-treated pulmonary artery endothelial cells.Cigarette smoke-enriched microR-1249 in endothelial extracellular vesicles facilitates the hyperproliferative and antiapoptotic status of pulmonary artery smooth muscle cells promoting pulmonary hypertension evolution through the inhibition of histone deacetylase 10-NFκB-calcium-sensing receptor cascade.

Extracellular vesicles

10.1161/hypertensionaha.122.19560

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Citations (17)

Optimization Analysis of Financial Shared Service Path under the Background of Accounting Information--Take FOSUN Group as an Example

Yu Fang Jing Jin Li Zhu

Based on the background of accounting information development, the establishment of a financial shared service center by enterprises provides a good value space for enterprise management decision-making, investment and operation. This article takes FOSUN Group as the case object, explores the problems of the financial sharing service center, provides a set of effective platform management mode to optimize the path, and improves the application level of accounting information. It aims to provide other similar enterprises in implementing the financial sharing mode and let other companies try to think from the three aspects of platform integration, project management, and performance optimization to provide guidance for the future development.

Financial Management

10.6981/fem.202105_2(5).0022

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Facile and Controlled Fabrication of Functional Gold Nanoparticle‐coated Polystyrene Composite Particle

Macromolecular Rapid Communications (2011)

Yunxing Li Yunfei Pan Li Zhu Zhaoqun Wang Dongmeng Su

Abstract Gold nanoparticles‐coated polystyrene (AuNPs‐coated PS) composite particles with raspberry‐like morphology are successfully prepared with the aid of a unique thermodynamically driving effect. It is of considerable interest that the AuNPs generate and self‐assemble with raw, ordinary PS microspheres that preexist in the oxidation–reduction systems. The synthesized AuNPs‐coated PS composite particles have been extensively characterized using scanning electron microscope, transmission electron microscope, and UV–Vis‐NIR spectroscopy. The results indicate that the morphology of the resultant composite particles is governed by simply changing the amount and type of reductants and the concentration of PS microspheres. The AuNPs‐coated PS composite particles also exhibit the good surface‐enhanced Raman scattering and catalytic performances. magnified image

Polystyrene

Particle (ecology)

10.1002/marc.201100377

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La0.5Sr0.5CoO2.91@RGO nanocomposites as an effective counter electrode for dye-sensitized solar cells

Journal of Materials Science Materials in Electronics (2016)

Kuangwei Xiong Zhongfei Liu Jiangtao Yuan Kunzhen Li Guang Li

Triiodide

Auxiliary electrode

10.1007/s10854-016-5712-x

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Citations (17)

BAND STRUCTURES IN DOUBLY ODD ¹²⁶I

Yi Zheng X. G. Wu C. Y. He G. S. LI Xiaotao Hao

Font

10.1142/9789814360654_0044

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Structural insights into sphingosine 1-phosphate receptor 4 activation

bioRxiv (Cold Spring Harbor Laboratory) (2024)

Wei Gao Shiyi Gan Mengting Zhang Asuka Inoue Mengting Xie

Abstract S1PR4 is one of five subtypes of sphingosine 1-phosphate receptors (S1PRs) that regulate immune cell functioning, with functional distinctions to other subtypes. S1PR1-targeted modulators caused serious cardiac and vascular adverse effects because S1PR1 was expressed throughout the whole body. Since S1PR4 was only expressed in lung and lymphoid cells, S1PR4-targeted modulators might not trigger these side effects. However, the development of S1PR4-specific agonists is greatly hindered because of the lack of activated S1PR4 structure. Here, we resolved cryo-EM structures of activated S1PR4 and revealed the structural mechanism of ligand recognition, receptor activation, and Gα i coupling. Our results offered structural templates for the development of selective S1PR4 agonists with improved safety profiles.

S1PR1

Sphingosine-1-phosphate receptor

10.1101/2024.03.02.583092

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THE POSITIVE-PARITY BAND STRUCTURES IN ¹⁰⁸Ag

C. LIU S. Y. WANG Bingkun Qi D. P. Sun Chengjie Xu

Font

Parity (physics)

10.1142/9789814360654_0021

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Testing unconditional and conditional independence via mutual information

Journal of Econometrics (2022)

Chunrong Ai Li-Hsien Sun Zheng Zhang Li Zhu

Independence

Conditional independence

Constant (computer programming)

10.1016/j.jeconom.2022.07.011

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Study on the Appearance Performance of Coffee Carbon and Graphene Nylon Far-infrared Seamless Knitted Fabric

Li Zhu Zimin Jin Ming‐Tao Zhao Jianwei Tao Yingjie Zheng

As the standards of living materials are being improved continuously, people are expecting more about clothing. Wearing fabrics are supposed to not only meet requirements for basic functions but also contact comfort and appearance performance. Based on this, in this paper we focus on the appearance performance of far-infrared seamless knitted fabrics. We choose coffee carbon and graphene nylon fibers as the veil fibers and then determine four yarn feeds ratio: 100:0; 75:25; 50:50; 25:75; three kinds of fabric weave: 1+3 rib structure, 1+1 fake rib structure, plain weave yarn adding structure, combined into 12 samples , which are studied form 3 aspects: crease resistance, drapability, and pilling resistance. After using a fuzzy comprehensive evaluation method to analyze both consumer survey and results of three experiments, and we conclude that the yarn feeds ratio and weave structure that meets the consumer's demand is feed ratio 75:25 and 1+1 fake rib structure of # 5, providing a reference for market applications.

Fabric structure

10.1109/iscid51228.2020.00023

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