Md Aftab Uddin

Stamford University Bangladesh

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Tasnia Ahmed

UNSW Sydney

Tasnim Jabin

Stamford University Bangladesh

Sitesh Chandra Bachar

University of Dhaka

Haseena Khan

University of Dhaka

Md. Miraj Kobad Chowdhury

University of Dhaka

Mohammad Riazul Islam

University of Dhaka

Rashed Noor

University of Mississippi Medical Center

Ruhul Kuddus

Utah Valley University

Raquiba Sultana

Stamford University Bangladesh

Kamal Kanta Das

Agartala Government Medical College

Cooperative Institutions

University of Dhaka

Stamford University Bangladesh

North South University

Bangladesh Agricultural University

Jahangirnagar University

International Centre for Diarrhoeal Disease Research

Bangabandhu Sheikh Mujib Medical University

Southeast University

University of Rajshahi

University of Chittagong

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Microbiological quality analysis of raw, pasteurized, UHT milk samples collected from different locations in Bangladesh

Stamford Journal of Microbiology (2015)

Sourav Kumar Banik Kamal Kanta Das Md Aftab Uddin

Present study attempted to determine the microbiological quality of raw, pasteurized and UHT (Ultra High Temperature-processed) milk samples collected from different locations in Bangladesh. A total of 46 samples were studied including 22 raw milk samples from the local dairy markets and 24 different brands of pasteurized and ultrahigh temperature (UHT) treated milk manufactured in different beverage industries. The samples were examined for determining the total viable bacterial count (TVBC) and total coliform count (TCC). Results revealed that the raw milk samples were substandard in terms of TVBC and TCC. The range of TVBC and TCC in raw milk samples was 5.2×108 to 1.3×107 cfu/ml and 4.2×104 to 1.0×104 cfu/ml, respectively. On the contrary, the quality of pasteurized and UHT-treated milks was excellent. The TVBC range in pasteurized milk samples was from 1.8×103 to 1.1×102 cfu/ml, slightly lower than that recommended by the Bangladesh Standards and Testing Institution (BSTI). Interestingly sample numbers P-6, P-10 and P-12 of pasteurized milk samples had no growth at all both in terms of TVBC and TCC and none of the UHT processed milk contained any bacteria. So from the consumer point of view, both types of processed milk can be considered safe for consumption within the mentioned expiry date. DOI: http://dx.doi.org/10.3329/sjm.v4i1.22753 Stamford Journal of Microbiology, Vol.4(1) 2014: 5-8

Pasteurization

10.3329/sjm.v4i1.22753

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Citations (29)

Isolation and quantification of microorganisms from some common milk products within Dhaka city, Bangladesh

Stamford Journal of Microbiology (2016)

M Malek Jasmin Akter Tasnia Ahmed Md Aftab Uddin

While milk is well known to be a balanced diet with its high nutritional values, conversely milk and milk products may serve as potential substrate for the growth and proliferation of a range of microorganisms which in turn fatally influences mass public health. Current study attempted to examine the likelihood of microbial contamination within some common milk products consumed by the locality of the city of Dhaka, Bangladesh. All samples exhibited the presence of bacterial and fungal contamination within a range of 102-104 cfu/mL and 102-103 cfu/mL, respectively. Among specific pathogens, Staphylococcus spp. was noticed to be the predominant ones and was recovered from 9 samples out of 20 samples in a range of 102-103 cfu/mL. Klebsiella spp. and Vibrio spp. were found within 6 and 9 samples, respectively. Products were also found to be contaminated with Vibrio spp. Study of antibiotic susceptibility test revealed that all the pathogenic bacteria were resistant against most of the commonly used antibiotics of which several isolates showed multi-drug resistant (MDR) trait. Therefore, the presence of pathogenic bacteria with the drug-resistance property in tested milk and milk products overall imparted the necessity of maintaining standardized hygienic handling and processing means for better management of public health.Stamford Journal of Microbiology, Vol.5(1) 2015: 13-17

Pathogenic bacteria

Isolation

Klebsiella

10.3329/sjm.v5i1.26913

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The Microbiological Quality of Commercial Fruit Juices-Current perspectives

Bangladesh Journal of Microbiology (2019)

Tasnia Ahmed Kamal Kanta Das Md Aftab Uddin

The purpose of this review article is to introduce the importance of fruit juices for human health living in the country and in a broad, and to develop awareness among the people about the diseases caused by pathogens associated with fruit juice. Health benefits of juices have been included in this article and how the same juice can cause problems among people of different ages have been discussed. Contamination sources and the ways to prevent them is very important issue in protecting public health Some future recommendations for fruit juices have also been added in this article. Different diseases caused by various microbial agents and the associated symptoms after consuming contaminated fruit juices worldwide are discussed in this review. This review was aimed at the possible sources of microbial contamination, disease caused by them and determining some ways to avoid such phenomena. From the information provided here, it was noticeable that commercial fruit juice can also harbor pathogenic microorganisms which can cause serious disease outbreaks. The contamination can also be initiated during in house consumption if lack of awareness prevails among the consumers. Manufacturing process should be much more strict in this regard to assure the public health safety. Commercially available fruit juices are consumed worldwide among different ages of people and if not processed properly, this healthy drink may be hazardous for human health. Bangladesh J Microbiol, Volume 35 Number 2 December 2018, pp 128-133

Fruit juice

Consumption

Health Benefits

10.3329/bjm.v35i2.42643

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Isolation and quantification of bacterial isolates from citrus fruits and determination of their anti-bacterial activity against selected pathogens

Stamford Journal of Microbiology (2015)

Rowshan Akter Nusrat Islam Tanu Md Aftab Uddin

The present study was undertaken with the aim of investigating the isolation and quantification of microorganisms from the citrus fruit samples collected from different areas of Dhaka city. Out of ten samples studied, the range of total viable bacterial proliferation was approximately 102 to 107 cfu/g. Among the specific bacterial pathogens, prevalence of Klebsiella spp. was found in five samples, Listeria spp., Staphylococcus spp. and Pseudomonas spp. in four samples and Vibrio spp. in three samples only. The presumptive identification of these isolates was done by the conventional cultural, microscopic and biochemical tests. Fungal growth was also observed in four samples within the range of 1.2×103 to 3.6×103 cfu/g. Interestingly, Prunus mume/domestica (plum) showed the anti-bacterial activity against all the laboratory bacterial isolates tested. Among other samples, Tanarindus bacilus (tamarind) was found to exhibit activity against Escherichia coli, Pseudomonas spp., Salmonella spp., Vibrio spp., and Listeria spp. On the other hand, Monifera indica (mango) showed anti-bacterial efficacy against E. coli, Staphylococcus spp. and Listeria spp. and Citrus limon (lemon) only against Pseudomonas spp. and Listeria spp. DOI: http://dx.doi.org/10.3329/sjm.v3i1.22750 Stamford Journal of Microbiology, Vol.3(1) 2013: 30-33

Isolation

Klebsiella

10.3329/sjm.v3i1.22750

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Citations (1)

International Journal of Pharmaceutical Sciences and Research (2015)

Md. Forhad Uddin Md Aftab Uddin Mohammed Abul Manchur Md. Sahab Uddin

The use of natural products for the treatment of various diseases has a long history.In the present study, the anti-oxidative, cytotoxic and phytochemical properties of ethanol extract of a local variety of Piper betle leaves cultivated in Potia, Bangladesh has been investigated.The antioxidant and cytotoxic activity of the Piper betle ethanol extract were evaluated by DPPH (1, 1-diphenyl-2picrylhydrazyl) free radical scavenging method and brine shrimp lethality bioassay method, respectively.Preliminary phytochemical group tests were also done to investigate the phytochemical properties of the extract.Leaf extract showed significant DPPH free radical scavenging effect compared to standard antioxidant ascorbic acid.IC 50 value of ascorbic acid and leaf extract was found 1.81μg/ml and 151.36μg/ml respectively.In brine shrimp lethality bioassay LC 50 value of Piper betle ethanol extract was found 274.63862µg/ml with 95% confidence limit where the lower and upper limits were 198.39 µg/ml and 387.18µg/ml respectively, which indicates that the Piper betle leaf extract has promising cytotoxic effect.Phytochemical analysis was found to be positive for alkaloid, glycosides, terpenoids, flavonoids, tannins and saponins.The present study demonstrates that ethanol extract of Piper betle Linn.Leaf has significant antioxidant and cytotoxic effect. INTRODUCTION:Piper betle commonly called betel leaf is a climbing shrub or small tree indigenous to tropical Asia, Australasia, and the Pacific and grown mostly in Bangladesh, India, China, Bhutan, and Malaysia 1-3 .The betel plant is an evergreen and perennial creeper, with glossy heart-shaped leaves and white catkin.The medicinal properties of betel leaf are well known since time immemorial.Traditionally the leaves are used to treat various diseases like halitosis, boils and abscesses, conjunctivitis, constipation, swelling of gums, cuts and injuries.The essential oil contained in the leaves is known to possess antibacterial, anti-protozoan and anti-fungal properties.

10.13040/ijpsr.0975-8232.6(10).4252-58

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Evaluation of Antioxidant, Cytotoxic, Antibacterial and Thrombolytic Activity of the Methanolic Extracts of Ficus racemosa Fruits

Journal of Complementary and Alternative Medical Research (2018)

Mst Shirajum Munira Md Aftab Uddin Md. Shariful Islam Koly Aktar Md. Abdul Muhit

Ficus

10.9734/jocamr/2018/40429

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Citations (7)

Misdiagnosis of Bacterial Pathogens by the Diagnostic Centers: A Potential Route for Antibiotic Resistance

Journal of Applied Pharmaceutical Science (2023)

Shanaz Fatema Bristy Md. Reaz Uddin Nowshin Jahan Dewan Zubaer Islam Bushra Ayat Meghla

Functional analysis of ATP-binding cassette transporter of Streptomyces coelicolorTu Nguyen and Huu Nguyen

10.7324/japs.2024.175488

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Microbiological and Antibiogram Profiling of Frozen Foods and Ice Cream Products from Super-Shops of Dhaka, Bangladesh

Stamford Journal of Microbiology (2024)

Sawda Binte Monir Md Hasan Md Aftab Uddin

The current study was conducted to assess the microbiological loads and antibiotic resistance patterns among 20 frozen food and ice cream samples that were gathered from multiple super-shops in Dhaka, Bangladesh. A total of 20 samples (11 frozen food samples and 9 ice cream samples) were collected from different supershops in Dhaka, Bangladesh during the period from July 2024 to September 2024. Microbiological analyses were performed to determine the total viable bacterial count (TVBC), total coliform count (TCC), and total staphylococcal count (TSC). The highest total viable bacterial count (2.12×109 cfu/g), highest coliform count (3.7×107 cfu/g), and highest staphylococcal count (2.04×108 cfu/g) were found in the frozen fish sample. Bacteria were isolated and identified based on their morphological and biochemical characteristics. While E. coli and Klebsiella spp. were observed in seven samples, Staphylococcus aureus was identified in twelve. Additionally, different antimicrobial agents were used to determine the isolates' susceptibility towards them. Ciprofloxacin, Imipenem, and Gentamicin have been demonstrated to be the most effective drugs against each isolate. All of the Klebsiella isolates exhibited sensitivity to Chloramphenicol, whereas most of the E. coli isolates were sensitive to Erythromycin, Chloramphenicol, and Nalidixic acid. However, erythromycin and amoxicillin were found to be less effective against Staphylococcus aureus isolates. The presence of several different microorganisms suggests that the majority of frozen food samples did not meet public health standards. These frozen foods, contaminated with multi-antibiotic-resistant microorganisms, have the potential to transmit food-borne diseases. Stam. J. Microbiol. 2024; 14(1): 22-27

Total Viable Count

10.3329/sjm.v14i1.78628

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Jute endophyte Grammothele lineata SDL-CO-2015-1 produces an anticancer compound epothilone B

Journal of Bangladesh Academy of Sciences (2023)

Mirza Ashikul Beg Sumaiya Binte Hannan Rabeya Shafi Ahmad Talukder Md Aftab Uddin

Jute (Corchorus olitorius) endophytic fungi Grammothele lineata SDL-CO-2015-1 was found to produce epothilone B, a well-reported anticancer compound. Both the genome and RNA-seq data of G. lineata revealed the presence of epothilone gene clusters. In silico mining using NaPDoS (Natural Product Domain Seeker) identified four genes matching with the epothilone gene cluster (Epo D). Epothilone was extracted from the extracellular extract of this fungus using XAD-16 resin. Different analytical techniques including thin layer chromatography (TLC), reverse phase high-performance liquid chromatography (RP-HPLC), and mass spectrometry (MS) were used to identify and characterize epothilone following its extraction. TLC bands were visible at 365 nm for both standard epothilone B and samples with identical Rf values. Extracted epothilone bands from the TLC plate were further purified using RP-HPLC. Using a linear gradient system with methanol and 0.1% formic acid, LC-MS spectroscopy was done with RP-HPLC purified fraction. The monoisotopic mass of epothilone (M+H+) = 508.1 Da was present in the mass chromatogram. The product ions of 508.1 Da were found with the m/z values at 320.2 Da, and 420.2 Da, the typical MS2 fragments for standard epothilone B. This finding suggests that the fungal endophyte, G. lineata can be a potential source of epothilone B. J. Bangladesh Acad. Sci. 47(1); 91-99: June 2023

Epothilones

10.3329/jbas.v47i1.65129

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Assessment of Knowledge and Awareness about Atherosclerosis and Incidence of Cardiovascular Events among Undergraduate Pharmacy Students in Bangladesh

British Journal of Pharmaceutical Research (2015)

Md Aftab Uddin Md Asaduzzaman Abdullah Al Mamun Mamunur Rashid

Journal of Pharmaceutical Research International (ISSN: 2456-9119) is dedicated to publish high quality papers in all areas of pharmaceutical Science including pharmaceutical drugs, community pharmacy, hospital pharmacy, clinical pharmacy, compounding pharmacy, consultant pharmacy, internet pharmacy, veterinary pharmacy, nuclear pharmacy, military pharmacy, pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, clinical pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics, pharmacoepidemiology, toxicology, theoretical pharmacology, posology, pharmacognosy, behavioral pharmacology, environmental pharmacology, medicine development and safety testing, drug legislation and safety, pharmaceutical microbiology, pharmaceutical molecular biology, pharmaceutical biotechnology. The journal also encourages the submission of useful reports of negative results. This is a quality controlled, OPEN peer reviewed, open access INTERNATIONAL journal.

Pharmacogenomics

Clinical Pharmacology

10.9734/bjpr/2016/22068

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Citations (2)