Qian Shi

Wenzhou University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Rong Cao

Fujian Institute of Research on the Structure of Matter

100

Maochun Hong

Fujian Institute of Research on the Structure of Matter

Daofeng Sun

China University of Petroleum, East China

Kuo‐Hsiung Lee

China Medical University Hospital

Xin‐Hua Li

Wenzhou University

Lijin Xu

Renmin University of China

Wenhua Bi

Weifang Chinese Medicine Hospital

Yucang Liang

University of Tübingen

Mao‐Lin Hu

Wenzhou University

Kenneth F. Bastow

University of North Carolina at Chapel Hill

Cooperative Institutions

Chinese Academy of Sciences

223

Wenzhou University

121

Fudan University

117

University of Chinese Academy of Sciences

Nanjing University

Sun Yat-sen University

University of North Carolina at Chapel Hill

University of Science and Technology of China

Shanghai Jiao Tong University

Zhejiang University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Antitumor Agents. 250. Design and Synthesis of New Curcumin Analogues as Potential Anti-Prostate Cancer Agents

Journal of Medicinal Chemistry (2006)

Lin Li Qian Shi Alexander K. Nyarko Kenneth F. Bastow Chin‐Chung Wu

In a continuing study of curcumin analogues as potential drug candidates to treat prostate cancer at both androgen-dependent and androgen-refractory stages, we designed and synthesized over 40 new analogues classified into four series: monophenyl analogues (series A), heterocycle-containing analogues (series B), analogues bearing various substituents on the phenyl rings (series C), and analogues with various linkers (series D). These new compounds were tested for cytotoxicity against two human prostate cancer cell lines, androgen-dependent LNCaP and androgen-independent PC-3. Antiandrogenic activity was also evaluated in LNCaP cells and PC-3 cells transfected with wild-type androgen receptor. Ten compounds possessed potent cytotoxicity against both LNCaP and PC-3 cells, seven only against LNCaP, and one solely against PC-3. This study established an advanced structure−activity relationship (SAR), and these correlations will guide the further design of new curcumin analogues with better anti-prostate cancer activity.

Structure–activity relationship

10.1021/jm051043z

Cite

Citations (170)

Correction to “Modulated Cell Internalization Behavior of Icosahedral DNA Framework with Programmable Surface Modification”

Journal of the American Chemical Society (2024)

Kui Huang Qiulan Yang Min Bao Shengwen Wang Luming Zhao

Section (typography)

10.1021/jacs.4c16945

Cite

Citations (0)

Structural and opto-electric properties of Ga and F codoped ZnO thin films on PC substrates

Vacuum (2013)

Qian Shi Kesong Zhou Mingjiang Dai Songsheng Lin Hou Huijun

Polycarbonate

10.1016/j.vacuum.2013.01.008

Cite

Citations (15)

CCDC 202668: Experimental Crystal Structure Determination

The Cambridge Structural Database (2003)

Rong Cao Qian Shi Daofeng Sun Maochun Hong Wenghua Bi

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc6swpj

Cite

Citations (0)

CCDC 194381: Experimental Crystal Structure Determination

The Cambridge Structural Database (2004)

Wenhua Bi Daofeng Sun Rong Cao Xing Li Qian Shi

Crystal (programming language)

10.5517/cc6j8cb

Cite

Citations (0)

CCDC 603926: Experimental Crystal Structure Determination

The Cambridge Structural Database (2007)

Wenhua Bi Daofeng Sun Rong Cao Xing Li Qian Shi

10.5517/ccn8fht

Cite

Citations (0)

Table S2 from Intertumoral Heterogeneity of CD3+ and CD8+ T-Cell Densities in the Microenvironment of DNA Mismatch-Repair–Deficient Colon Cancers: Implications for Prognosis

Harry H. Yoon Qian Shi Erica N. Heying Andrea Murányi Joerg Bredno

Table S2: Association between immune T-cell subtypes in MMR-deficient and -proficient stage III colon cancers.

10.1158/1078-0432.22473720

Cite

Citations (0)

A spin Hall effect-based multi-level cell for MRAM

International Symposium on Nanoscale Architectures (2016)

Qian Shi Zhaohao Wang Yuqian Gao Liang Chang Wang Kang

Multi-level cell (MLC) is an efficient solution to improve the storage density of the MRAM. However, the conventional spin transfer torque-based MLC (STT-MLC) suffers from the performance bottlenecks such as high write energy and complicated two-step operation. In this work, we propose a spin Hall effect-based MLC (SHE-MLC) to overcome these bottlenecks. In the SHE-MLC structure, the write current does not pass the MTJ, which avoids the barrier breakdown and reduces the write energy. Moreover, the written data is only dependent on the direction of the write current, thus the two-step operation is not required. Simulation results demonstrate that, under the same access transistor size, e.g. 600 nm, the proposed SHE-MLC can achieve 55× faster write operation and 58× lower write energy than the conventional STT-MLC.

Magnetoresistive random-access memory

Spin-transfer torque

10.1145/2950067.2950104

Cite

Citations (2)

Synthesis of ultralong NiSe nanobelts and their excellent adsorption properties towards malachite green in water

RSC Advances (2016)

Cuijin Pei Hua Zhao Yan Zhao Bin Liu Guoping Han

NiSe ultralong nanobelts were synthesized by a solvothermal reaction of Ni with Se and KBH₄ in ethylenediamine and subsequent annealing in Ar, and employed as adsorbent for the removal of malachite green in wastewater.

Malachite green

Ethylene diamine

Malachite

10.1039/c6ra23119e

Cite

Citations (5)

CCDC 247383: Experimental Crystal Structure Determination

The Cambridge Structural Database (2004)

Xin‐Hua Li Qian Shi Mao‐Lin Hu Hong-Ping Xiao

10.5517/cc89f32

Cite

Citations (0)