Gan Liu

Qingdao University of Technology

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Lin Mei

Chinese Academy of Medical Sciences & Peking Union Medical College

Xiaowei Zeng

Sun Yat-sen University

Wei Tao

Brigham and Women's Hospital

Qiwen Kong

National University of Singapore

Chen Sun

National University of Singapore

Zuopu Zhou

National University of Singapore

Xiaolin Wang

National University of Singapore

Dong Zhang

Chinese Academy of Sciences

Yuye Kang

National University of Singapore

Zijie Zheng

National University of Singapore

Cooperative Institutions

Sun Yat-sen University

Nanjing University

Chinese Academy of Sciences

Collaborative Innovation Center of Advanced Microstructures

Tsinghua University

Huazhong University of Science and Technology

National University of Singapore

University Town of Shenzhen

Zhejiang University

University of Chinese Academy of Sciences

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CT findings in Swyer-James syndrome

Zhonghua fangshexian yixue zazhi (2002)

Gan Liu

Objective To evaluate the CT findings of Swyer-James syndrome. Methods In 28 patients(12 males,16 females; age range 11-57 years, mean 32 years), inspiratory chest X-ray films were performed, and 5 of them with expiratory chest films and 1 with bronchogram. Furthermore, inspiratory and expiratory CT scans were performed. The CT findings were analyzed and compared with that of X-ray films. Results CT demonstrated 56 lobes were hyperlucent and with decreased vascularity, and the size was small in 51 lobes(91%) and normal in 5 lobes. X-ray films showed that the hyperlucency was only in 29 lobes(52%), and 19 lobes(66%) with small size. Air trapping was detected in all 56 lobes on the expiratory CT scans, but in only 5 lobes on the expiratory X-ray films. In one case with bronchogram, bronchiectasis and bronchiolitis obliterans were demonstrated. CT showed 24 patients with bronchiectasis, 9 patients with TB,10 patients with bronchiolitis, and 2 with segmental collapse.Conclusion Inspiratory and expiratory CT scans are very useful for the diagnosis and the differential diagnosis of SJS.

Air trapping

Vascularity

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An Energy-Efficient Scheduling Algorithm for Real-Time Tasks

Lecture notes in computer science (2007)

Youlin Ruan Gan Liu Jian-Jun Han Qinghua Li

10.1007/978-3-540-72590-9_146

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Citations (1)

The pricing strategies in a new luxury goods manufacturer dominated supply chain

Jianyuan Yan Yuechao Sun Gan Liu

In the consumer market, new luxury brands (e.g. Emporio Armani, G-star, MiuMiu, Adidas Originals) usually act as the trendsetters and original designers, while some ordinary consumer goods' brands (e.g. H&M, ZARA, Xstep, MetersBonwe) prefer to be followers. A new luxury goods manufacturer is also in a dominant place, when facing the supplier (as well as the outsourcer). Whereas, the situation is different for the Ordinary consumer goods manufacturer. This article studys the pricing strategies of three participants in a new luxury goods manufacturer dominated supply chain and some influence factors, basing on Cournot model and stackelberg model. After calculation and comparison, we analysed the corresponding strategies manufacturers and the supplier should adopt, when market size, brand value and product cost are changing, under given settings. And generally, we find that manufacturers benefit more in stackelberg game than in Cournot game, while the supplier gets more profit in Cournot game.

Stackelberg competition

Luxury goods

10.1109/icsssm.2011.5959361

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Cooperative load-balancing strategy based on N-hops routing algorithm of ad hoc network in heterogeneous overlapping networks

Annals of Telecommunications (2008)

Xuebing Pei Guangxi Zhu Qingping Wang Gan Liu Wenpeng Yuan

WiMAX

10.1007/s12243-008-0062-1

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Citations (4)

Deep insights into the Interplay of Polarization Switching, Charge Trapping, and Soft Breakdown in Metal-Ferroelectric-Metal-Insulator-Semiconductor Structure: Experiment and Modeling

2022 International Electron Devices Meeting (IEDM) (2022)

Xiaolin Wang Chen Sun Zijie Zheng Leming Jiao Zuopu Zhou

We perform comprehensive experiment and modeling to understand the influence of ferroelectric (FE) polarization switching, charge trapping (CT) in floating gate (FG) from both control gate (CG) and channel, and soft breakdown (SBD) on the characteristics of the Fe-FETs having a metal-ferroelectric-metal-insulator-semiconductor (MFMIS) structure Assisted by extensive experiments and guided by rigorous understanding through experiment-simulation interaction, we discover: (1) SBD could happen as AR $(A_{Fe}/A_{MOS})$ reduces to a certain value through analysis of the devices with AR from 0.001 to 1; (2) previous FE-only based model without considering CT in FG and SBD fails to explain various trends in a wide range of AR. (3) The recently discovered phenomenon of MW being higher than 2V C (the limitation of Fe-FETs, V C is the coercive voltage of the ferroelectric layer) can be explained by the combined effect of CT in FG and SBD. These findings motivated us to develop a comprehensive and accurate FE &CT&SBD-based model which incorporates the impact of FE, CT in FG, and SBD. The excellent agreement between our model and the experimental data allows us to propose, for the first time, five operation modes of the MFMIS structure, providing the guidelines for device optimization and application.

Metal gate

10.1109/iedm45625.2022.10019390

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Citations (7)

DMABT: A Novel Distributed Medium Access Protocol with Busy Tone

IEEE Vehicular Technology Conference (2007)

Mingxin Chen Gan Liu Guangxi Zhu Di Wu Wenpeng Yuan

IEEE 802.11 standard is the most popular medium access control (MAC) protocol in distributed wireless networks. But the throughput of the network is restrained because of collisions and the idle slots wasted for competition. In this paper, we present a new Distributed Medium Access protocol with a busy tone (DMABT). In this protocol, a new backoff procedure is executed in the busy tone instead of the data channel and collision is reduced, so the throughput of the network is improved. A remarkable characteristic of this protocol is that it does not require extra transceiver for the busy tone, which does not increase the hardware cost of the mobile station. We study the performance of DMABT protocol through simulated experiments. The results show that DMABT protocol is more efficient than the one discussed in the IEEE 802.11e task group.

Media access control

Inter-Access Point Protocol

IEEE 802.1X

Idle

Transceiver

Network allocation vector

Tone (literature)

10.1109/vetecf.2007.342

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Citations (1)

DTX-loaded star-shaped TAPP-PLA-b-TPGS nanoparticles for cancer chemical and photodynamic combination therapy

RSC Advances (2015)

Teng Wang Dunwan Zhu Gan Liu Wei Tao Wei Cao

A novel star-shaped copolymer TAPP-PLA-b-TPGS was synthesized as drug nanocarriers for cancer chemical and photodynamic combination therapy.

Nanocarriers

Star (game theory)

Cancer Therapy

10.1039/c5ra09042c

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Citations (31)

Corrigendum to “Black phosphorus nanosheets-based stable drug delivery system via drug-self-stabilization for combined photothermal and chemo cancer therapy” [Chem. Eng. J. 375 (2019) 121917]

Chemical Engineering Journal (2021)

Gan Liu Hsiang-I Tsai Xiaowei Zeng Junyang Qi Miaomiao Luo

Black Phosphorus

Cancer Therapy

10.1016/j.cej.2021.128945

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First Demonstration of BEOL-Compatible MFMIS Fe-FETs with 3D Multi-Fin Floating Gate: In-situ ALD-deposited MFM, L_CH of 50 nm,> 2×10⁹ Endurance, and 58.3% Area Saving

2022 IEEE Symposium on VLSI Technology and Circuits (VLSI Technology and Circuits) (2023)

Xiaolin Wang Zijie Zheng Qiwen Kong Leming Jiao Kaizhen Han

Addressing the major concern of area-inefficiency for metal-ferroelectricmetal-insulator-semiconductor (MFMIS) ferroelectric FETs (Fe-FETs), for the first time, we demonstrate 3D MFMIS Fe-FETs employing Multi-Fin floating gate (FG) that enlarges the channel area and realizes desired area ratio (AR) at a fixed device footprint. Such novel device architecture realizes an AR of 1:2.4 with$\sim$58.3% area saving as compared with the conventional planar structure. Together with the incorporation of an in-situ ALD deposited ferroelectric layer and TiN electrodes, as well as the ALD-enabled conformal growth of HfO 2 dielectric layer and ZnO channel without breaking the vacuum for enhanced gate stack quality, the device with a channel length $(L_{\mathrm{C}\mathrm{H}})$ of 50 nm achieves a memory window (MW) of 1.5 V and endurance over $2\times 10^{9}$.

Metal gate

10.23919/vlsitechnologyandcir57934.2023.10185306

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Citations (3)

Iron Oxide Nanoparticles Induce Autophagosome Accumulation through Multiple Mechanisms: Lysosome Impairment, Mitochondrial Damage, and ER Stress

Molecular Pharmaceutics (2016)

Xu Dong Zhang Hong-Qiu Zhang Xin Liang Jinxie Zhang Wei Tao

Magnetite (iron oxide, Fe3O4) nanoparticles have been widely used for drug delivery and magnetic resonance imaging (MRI). Previous studies have shown that many metal-based nanoparticles including Fe3O4 nanoparticles can induce autophagosome accumulation in treated cells. However, the underlying mechanism is still not clear. To investigate the biosafety of Fe3O4 and PLGA-coated Fe3O4 nanoparticles, some experiments related to the mechanism of autophagy induction by these nanoparticles have been investigated. In this study, the results showed that Fe3O4, PLGA-coated Fe3O4, and PLGA nanoparticles could be taken up by the cells through cellular endocytosis. Fe3O4 nanoparticles extensively impair lysosomes and lead to the accumulation of LC3-positive autophagosomes, while PLGA-coated Fe3O4 nanoparticles reduce this destructive effect on lysosomes. Moreover, Fe3O4 nanoparticles could also cause mitochondrial damage and ER and Golgi body stresses, which induce autophagy, while PLGA-coated Fe3O4 nanoparticles reduce the destructive effect on these organelles. Thus, the Fe3O4 nanoparticle-induced autophagosome accumulation may be caused by multiple mechanisms. The autophagosome accumulation induced by Fe3O4 was also investigated. The Fe3O4, PLGA-coated Fe3O4, and PLGA nanoparticle-treated mice were sacrificed to evaluate the toxicity of these nanoparticles on the mice. The data showed that Fe3O4 nanoparticle treated mice would lead to the extensive accumulation of autophagosomes in the kidney and spleen in comparison to the PLGA-coated Fe3O4 and PLGA nanoparticles. Our data clarifies the mechanism by which Fe3O4 induces autophagosome accumulation and the mechanism of its toxicity on cell organelles and mice organs. These findings may have an important impact on the clinical application of Fe3O4 based nanoparticles.

Autophagosome

PLGA

Iron oxide nanoparticles

10.1021/acs.molpharmaceut.6b00405

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Citations (130)