Ziyuan Liu

Peking University Third Hospital

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Xuemin Li

Peking University

Jie He

South China University of Technology

Xuejiao Shi

First Affiliated Hospital of Anhui Medical University

Zhaoli Chen

Academy of Military Medical Sciences

Kang Shao

Chinese Academy of Medical Sciences & Peking Union Medical College

Max Y.F He

Chinese Academy of Medical Sciences & Peking Union Medical College

Fengwei Tan

Chinese Academy of Medical Sciences & Peking Union Medical College

Yibo Gao

Chinese Academy of Medical Sciences & Peking Union Medical College

Suya Wang

Southern Medical University

Bin Qiu

Jiangnan University

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Peking University

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Peking University Third Hospital

University of Cambridge

Neurological Surgery

Chinese Academy of Sciences

National Institute for Health Research

Chinese Academy of Medical Sciences & Peking Union Medical College

Addenbrooke's Hospital

University of Birmingham

Nanjing Medical University

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Supplementary Materials from Isocitrate Dehydrogenase 1 Is a Novel Plasma Biomarker for the Diagnosis of Non–Small Cell Lung Cancer

Nan Sun Zhaoli Chen Fengwei Tan Baihua Zhang Ran Yao

<p>Statistical process of grouping and modeling</p>

Isocitrate dehydrogenase

10.1158/1078-0432.22452683.v1

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In Vivo Biomechanical Measurements of the Cornea

Bioengineering (2023)

Fanshu Li Kehao Wang Ziyuan Liu

In early corneal examinations, the relationships between the morphological and biomechanical features of the cornea were unclear. Although consistent links have been demonstrated between the two in certain cases, these are not valid in many diseased states. An accurate assessment of the corneal biomechanical properties is essential for understanding the condition of the cornea. Studies on corneal biomechanics in vivo suggest that clinical problems such as refractive surgery and ectatic corneal disease are closely related to changes in biomechanical parameters. Current techniques are available to assess the mechanical characteristics of the cornea in vivo. Accordingly, various attempts have been expended to obtain the relevant mechanical parameters from different perspectives, using the air-puff method, ultrasound, optical techniques, and finite element analyses. However, a measurement technique that can comprehensively reflect the full mechanical characteristics of the cornea (gold standard) has not yet been developed. We review herein the in vivo measurement techniques used to assess corneal biomechanics, and discuss their advantages and limitations to provide a comprehensive introduction to the current state of technical development to support more accurate clinical decisions.

Biomechanics

Refractive Surgery

10.3390/bioengineering10010120

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Citations (3)

ATF4-mediated circTDRD3 promotes gastric cancer cell proliferation and metastasis by regulating the miR-891b/ITGA2 axis and AKT signaling pathway

Gastric Cancer (2023)

Peng Zhou Huiheng Qu Kaihang Shi Xingyu Chen Zequn Zhuang

Surgical oncology

10.1007/s10120-023-01392-3

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Citations (5)

O-MN004. The selective and inverse u-shape curve alteration of retinal nerve fiber layer in ALS: A potential mirror of the disease

Clinical Neurophysiology (2021)

Yixuan Zhang Xiangyi Liu Ziyuan Liu Xue Yang Yuanjin Zhang

Nerve fiber

10.1016/j.clinph.2021.02.147

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An Epidemiological Study of Lung Cancer in Xuan Wei County, China: Current Progress. Case-Control Study on Lung Cancer and Cooking Fuel

Environmental Health Perspectives (1991)

Xingzhou He Wei Chen Ziyuan Liu Robert S. Chapman

10.2307/3431286

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Citations (51)

Table S1 from Isocitrate Dehydrogenase 1 Is a Novel Plasma Biomarker for the Diagnosis of Non–Small Cell Lung Cancer

Nan Sun Zhaoli Chen Fengwei Tan Baihua Zhang Ran Yao

<p>The equations used in the models, which were obtained by binary logistic regression.</p>

Isocitrate dehydrogenase

Table (database)

10.1158/1078-0432.22452680.v1

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Vision function of pseudophakic eyes with posterior capsular opacification under different speed and spatial frequency

International Ophthalmology (2020)

Ziyuan Liu Zhiqiang Hou Shan Ge Honglei Pang Wei Wang

10.1007/s10792-020-01536-9

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Citations (3)

Comparison of Patient Outcomes following Implantation of Trifocal and Extended Depth of Focus Intraocular Lenses: A Systematic Review and Meta-Analysis

Journal of Ophthalmology (2021)

Yining Guo Yinhao Wang Ran Hao Xiaodan Jiang Ziyuan Liu

Purpose. The purpose is to compare the outcomes of implantation of trifocal intraocular lenses (TIOLs) and extended depth of focus (EDOF) intraocular lenses (IOLs). Methods. A comprehensive search of PubMed, Cochrane Library, EMBASE, and ClinicalTrial.gov was conducted in March 2020 to identify relevant studies. A meta-analysis of the results was performed. Patients implanted with EDOF IOLs or TIOLs in previous studies were included. The primary outcomes of the study were uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), and defocus curve. Results. TIOLs and EDOF IOLs provided comparable binocular UDVA (MD = -0.01, 95% CI: -0.04, 0.03, logMAR). However, EDOF IOLs provided better UIVA (MD: -0.08, 95% CI: -0.14, -0.01, logMAR) and worse UNVA (MD: 0.10, 95% CI: 0.06, 0.14, logMAR) than TIOLs. Fewer patients achieved spectacle independence after implantation of EDOF IOLs (RR: 0.74, 95% CI: 0.63, 0.87) than after implantation of TIOLs, especially for near vision (RR = 0.82, 95% CI: 0.68, 0.99). There was no statistically significant difference in contrast sensitivity (CS) under photopic or mesopic conditions with both IOLs. Patient satisfaction after implantation of both IOLs was high. Conclusion. EDOF IOLs and TIOLs provide comparable distance vision. However, EDOF IOLs provide better intermediate vision and worse near vision than TIOLs. The advantages of EDOF IOLs over TIOLs in terms of CS, aberrations, and visual disturbance are not significant. Patients are satisfied with both types of IOLs.

Mesopic vision

Intraocular lenses

10.1155/2021/1115076

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Citations (23)

Double Corneal Arcus

New England Journal of Medicine (2024)

Ziyuan Liu Wei Wang

A 63-year-old woman was noted to have white-yellow rings in both eyes. On slit-lamp examination, two concentric rings were seen in each cornea.

10.1056/nejmicm2313156

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Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Journal of Visualized Experiments (2023)

Di Zhang Ziyuan Liu Hongyuan Cai Haikun Wang Xiaoyong Chen

Posterior capsule opacification (PCO) is a common postoperative complication of extracapsular cataract surgery, which is caused by the proliferation and migration of lens epithelial cells and can affect long-term visual outcomes significantly. The most effective treatment for PCO is neodymium-doped yttrium aluminum garnet (Nd:YAG) laser capsulotomy; however, this treatment is associated with posterior segment complication and can break the stability of capsular bag, affecting the position and function of trifocal or toric intraocular lenses (IOLs). Advances in surgical procedures, IOL design, and pharmacy have reduced the rate of PCO in recent years, concentrating on the inhibition of proliferative lens epithelial cells (LECs). This protocol aimed to clear LECs more thoroughly during phacoemulsification and IOL implantation. The first several steps, including clear corneal incision, continuous circular capsulorhexis, hydrodissection, hydrodelineation, and phacoemulsification, were completed as conventional procedures. After placing the IOL into the capsular bag, rotation of the IOL by at least 360° was performed using an irrigation/aspiration tip or a hook, with slight stress on the posterior capsule. Some residuals occurred in the originally transparent capsular bag after rotation of the IOLs. Then, these materials and the viscoelastic were cleared completely using an irrigation/aspiration system. A clear posterior capsule was observed after the surgery in patients undergoing this method. This method of rotating IOLs is a simple, effective, and safe way to prevent PCO by clearing residual LECs and can be carried out without extra tools or skills.

Capsulorhexis

Posterior Capsule Opacification

Centration

Clearance

Posterior Capsulotomy

10.3791/65419

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Citations (1)